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3 papers found.
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Efficacy and safety of rotigotine in elderly patients with Parkinson’s disease in comparison with the non-elderly: a post hoc analysis of randomized, double-blind, placebo-controlled trials

Rotigotine—a non-ergot dopamine agonist—has two advantages; it can stimulate all dopamine receptors (D1–D5) like innate dopamine, and its transdermal administration provides continuous dopaminergic stimulation. The age of the patient impacts the effect and adverse events of anti-parkinsonian treatment. We conducted a post hoc analysis on three randomized, double-blind, placebo...

Can serum albumin level affect the pharmacological action of tolvaptan in patients with liver cirrhosis? A post hoc analysis of previous clinical trials in Japan

. Sayaka Tachikawa, Masaya Sakurai, and Yoshiyuki Shibasaki contributed to data analysis and interpretation of the data, take responsibility for the integrity of the data and accuracy of the data analysis ... Okita is a consultant for Otsuka Pharmaceutical. Masatsugu Hori is a consultant for Otsuka Pharmaceutical. Tohru Izumi is a consultant for Otsuka Pharmaceutical. Koji Nakajima, Masaya Sakurai, Yoshiyuki