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28 papers found.
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Tenofovir disoproxil fumarate reduce incidence of HCC development in CHB-patients with compensated cirrhosis

The impact of different anti-virus regimens on prognosis of Chronic hepatitis B (CHB) related cirrhosis remains to be explored. We aim to investigate whether CHB-related HCC patients receiving nucleoside analogue regimen or not have a different prognosis. Two hundred forty-two CHB-related compensated cirrhosis patients were attributed into groups regarding their anti-virus...

The optimal time to inject bone mesenchymal stem cells for fracture healing in a murine model

BackgroundBone marrow is an important source of stem cells, which can promote bone fracture healing.MethodsWe investigated the optimal time to inject bone marrow mesenchymal stem cells (BMSCs) in a C57 murine unilateral, transverse, femur fracture model. BMSCs transfected with red fluorescent protein (RFP-BMSCs) were injected via the tail vein on day 1, 7, or 14 post-fracture...

Effects of the particle of ground alfalfa hay on the growth performance, methane production and archaeal populations of rabbits

, Tianhai Yan. Investigation: Mei Yuan, Jingyi Cai. Resources: Gang Tian. Software: Mei Yuan, Dingxing Jin. Supervision: Zhisheng Wang, Huawei Zou. Validation: Bai Xue. Visualization: Mei Yuan. Writing

Prognostic Impact of the Findings on Thin-Section Computed Tomography in stage I lung adenocarcinoma with visceral pleural invasion

resolved: all authors; literature research: Mei Yuan, Jin-Yuan Liu, Teng Zhang, Tong-Fu Yu; clinical studies: Mei Yuan, Jin-Yuan Liu, Teng Zhang, Yu-Dong Zhang, Tong-Fu Yu; statistical analysis: Mei Yuan ... , Jin-Yuan Liu, and manuscript editing: Mei Yuan, Teng Zhang, Tong-Fu Yu. Additional Information Competing Interests: The authors declare no competing interests. Publisher's note: Springer Nature

Impact Localization Method for Composite Plate Based on Low Sampling Rate Embedded Fiber Bragg Grating Sensors

Changcheng Institute of Metrology and Measurement, The Aviation Industry Corporation of China, Beijing 100095, China Correspondence should be addressed to Mei Yuan; nc.ude.aaub@mnauy Received 24 March 2017

Genomic and Transcriptomic Analysis Identified Gene Clusters and Candidate Genes for Oil Content in Peanut (Arachis hypogaea L.)

Peanut (Arachis hypogaea), a major source of vegetable oil in many Asian countries, has become an integral part of human diet globally due to its high nutritional properties and option to consume in different forms. In order to meet the demand of vegetable oil, many peanut breeding programs of China have intensified their efforts in increasing oil content in newly bred varieties...

IFN-λ1 in CHO cells: its expression and biological activity

Background Many studies have investigated the characteristics and biological activities of type III interferon (IFN), finding that it has similar features to type I IFN but also unique actions because it is recognized by a different receptor. Results A full-length recombinant human IFN-λ1 (rhIFN-λ1) cDNA was cloned into the pDF expression vector and stably expressed in Flp-In-CHO...

Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma

, Kar-Wai Lui2, Lang-Ming Chi3, Yung-Chia Kuo1, Yin-Kai Chao4, Chun-Nan Yeh5, Li-Yu Lee6, Yenlin Huang6, Tung-Liang Lin1, Mei-Yuan Huang7, Yi-Ru Lai7, Yuan-Ming Yeh8, Hsien-Chi Fan1, An-Chi Lin1, Yen-Jung

The surface properties of aluminated meso–macroporous silica and its catalytic performance as hydrodesulfurization catalyst support

Aluminated mesoporous silica was prepared by multiple post-grafting of alumina onto uniform mesoporous SiO2, which was assembled from monodisperse SiO2 microspheres. Hydrodesulfurization (HDS) catalyst was prepared by loading Ni and Mo active components onto the aluminated uniform mesoporous SiO2, and its HDS catalytic performance was evaluated using hydrodesulfurization of...

QTL mapping for bacterial wilt resistance in peanut (Arachis hypogaea L.)

Bacterial wilt (BW) caused by Ralstonia solanacearum is a serious, global, disease of peanut (Arachis hypogaea L.), but it is especially destructive in China. Identification of DNA markers linked to the resistance to this disease will help peanut breeders efficiently develop resistant cultivars through molecular breeding. A F2 population, from a cross between disease-resistant...

Human polyomavirus type six in respiratory samples from hospitalized children with respiratory tract infections in Beijing, China

Background HPyV6 is a novel human polyomavirus (HPyV), and neither its natural history nor its prevalence in human disease is well known. Therefore, the epidemiology and phylogenetic status of HPyV6 must be systematically characterized. Methods The VP1 gene of HPyV6 was detected with an established TaqMan real-time PCR from nasopharyngeal aspirate specimens collected from...

Prognostic value of secreted phosphoprotein-1 in pleural effusion associated with non-small cell lung cancer

Background Malignant pleural effusion (MPE) is a common complication of advanced lung cancer. Research has shown that secreted phosphoprotein-1 (SPP1) is essential in MPE associated with lung cancer. This retrospective study was performed to evaluate the prognostic significance of SPP1 in the MPE of patients with non-small cell lung cancer (NSCLC). Methods MPE specimens were...

Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration

The meniscus plays a crucial role in maintaining knee joint homoeostasis. Meniscal lesions are relatively common in the knee joint and are typically categorized into various types. However, it is difficult for inner avascular meniscal lesions to self-heal. Untreated meniscal lesions lead to meniscal extrusions in the long-term and gradually trigger the development of knee...

Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration

The meniscus plays a crucial role in maintaining knee joint homoeostasis. Meniscal lesions are relatively common in the knee joint and are typically categorized into various types. However, it is difficult for inner avascular meniscal lesions to self-heal. Untreated meniscal lesions lead to meniscal extrusions in the long-term and gradually trigger the development of knee...

Skin Rash could Predict the Response to EGFR Tyrosine Kinase Inhibitor and the Prognosis for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis

Background The aim of this study was to assess the role of skin rash in predicting the efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and the prognosis of patients with non-small cell lung cancer (NSCLC). Method We systematically searched for eligible articles investigating the association between rash and the efficacy of EGFR-TKIs and the...

miR-26a Suppresses Tumor Growth and Metastasis by Targeting FGF9 in Gastric Cancer

The role of miR-26a in cancer cells seemed controversial in previous studies. Until now, the role of miR-26a in gastric cancer remains undefined. In this study, we found that miR-26a was strongly downregulated in gastric cancer (GC) tissues and cell lines, and its expression levels were associated with lymph node metastasis and clinical stage, as well as overall survival and...

First report on the occurrence of Rickettsia slovaca and Rickettsia raoultii in Dermacentor silvarum in China

0 Mei-Yuan Tian 0 0 State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of

Effect of Cervus and Cucumis Peptides on Osteoblast Activity and Fracture Healing in Osteoporotic Bone

Osteoporosis is associated with delayed and/or reduced fracture healing. As cervus and cucumis are the traditional Chinese treatments for rheumatoid arthritis, we investigated the effect of supplementation of these peptides (CCP) on bone fracture healing in ovariectomized (OVX) osteoporotic rats in vitro and in vivo. CCP enhanced osteoblast proliferation and increased alkaline...

Reduced expression of p21-activated protein kinase 1 correlates with poor histological differentiation in pancreatic cancer

Background P21-activated protein kinase 1 (PAK1), a main downstream effector of small Rho GTPases, is overexpressed in many malignancies. PAK1 overexpression is associated with poor prognosis in some tumor types, including breast cancer, gastric cancer, and colorectal cancer. However, the expression and clinical relevance of PAK1 expression in human pancreatic cancer remains...

Antitumor activity of mixed heat shock protein/peptide vaccine and cyclophosphamide plus interleukin-12 in mice sarcoma

Background The immune factors heat shock protein (HSP)/peptides (HSP/Ps) can induce both adaptive and innate immune responses. Treatment with HSP/Ps in cancer cell-bearing mice and cancer patients revealed antitumor immune activity. We aimed to develop immunotherapy strategies by vaccination with a mixture of HSP/Ps (mHSP/Ps, HSP60, HSP70, Gp96 and HSP110) enhanced with...