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9 papers found.
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Laparoscopic-assisted cyst excision and ductoplasty plus widened portoenterostomy for choledochal cysts with a narrow portal bile duct

by National Health and Family Planning Commission of the People’s Republic of China with Grant No. 201402007. Compliance with ethical standards Disclosures Xiaopan Chang, Xi Zhang, Meng Xiong, Li Yang

Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer

Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer Wen Yuan,1,2,* Songping Xie,3,* Meng Wang,2 Shan Pan,2 Xiaoxing Huang,2 Meng Xiong,2 Rui-jing Xiao,2 Jie Xiong,2

CCR9 in cancer: oncogenic role and therapeutic targeting

Cancer is currently one of the leading causes of death worldwide and is one of the most challenging major public health problems. The main challenges faced by clinicians in the management and treatment of cancer mainly arise from difficulties in early diagnosis and the emergence of tumor chemoresistance and metastasis. The structures of chemokine receptor 9 (CCR9) and its...

CCR9 in cancer: oncogenic role and therapeutic targeting

Cancer is currently one of the leading causes of death worldwide and is one of the most challenging major public health problems. The main challenges faced by clinicians in the management and treatment of cancer mainly arise from difficulties in early diagnosis and the emergence of tumor chemoresistance and metastasis. The structures of chemokine receptor 9 (CCR9) and its...

Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy

Background Trimetazidine, as an anti-ischemic and antioxidant agent, has been demonstrated to have many cardioprotective effects. However, whether early administration of trimetazidine has an effect on diabetic cardiomyopathy and the mechanisms underlying the effect have not yet been elucidated. Methods We established a type 2 DCM rat model by high-fat diet and low-dose...

Pitavastatin calcium improves endothelial function and delays the progress of atherosclerosis in patients with hypercholesterolemia

Jing ZHAO, Hui-min YAN, Ya LI, Jia WANG, Lu HAN, Zhi-hao WANG, Meng-xiong TANG, Wei ZHANG, Yun ZHANG, and Ming ZHONG declare that they have no conflict of interest. All procedures followed were in

Visceral adiposity index score indicated the severity of coronary heart disease in Chinese adults

Background Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac structure and function and assess the impact of the cut-off points of VAI defining visceral adipose dysfunction (VAD) on the severity of coronary heart disease (CHD...

Overexpressing STAMP2 Improves Insulin Resistance in Diabetic ApoE−/−/LDLR−/− Mice via Macrophage Polarization Shift in Adipose Tissues

STAMP2 is a counterregulator of inflammation and insulin resistance. The aim of this study is to investigate whether activation of STAMP2 improves insulin resistance by regulating macrophage polarization in adipose tissues. The diabetic ApoE−/−/LDLR−/− mouse model was induced by high-fat diet and low-dose streptozotocin. Samples were obtained from epididymal, subcutaneous and...