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AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria

AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria Qinglin Li,1 Meng Zhao,2

A Method Adjusting Consistency and Consensus for Group Decision-Making Problems with Hesitant Fuzzy Linguistic Preference Relations Based on Discrete Fuzzy Numbers

Management and Economics, Tianjin University, 300072, China 4School of Public Affairs, Zhejiang University, Hangzhou 310058, China Correspondence should be addressed to Meng Zhao; moc.361@8002705gnemgnin ... Received 25 December 2017; Accepted 23 May 2018; Published 12 July 2018 Academic Editor: Danilo Comminiello Copyright © 2018 Meng Zhao et al. This is an open access article distributed under the Creative

Menin Modulates Mammary Epithelial Cell Numbers in Bovine Mammary Glands Through Cyclin D1

Menin, the protein encoded by the MEN1 gene, is abundantly expressed in the epithelial cells of mammary glands. Here, we found MEN1/menin expression slowly decreased with advancing lactation but increased by the end of lactation. It happened that the number of bovine mammary epithelial cells decreases since lactation, suggesting a role of menin in the control of mammary...

Outcomes of renal function in elderly patients with acute kidney injury

Outcomes of renal function in elderly patients with acute kidney injury Qinglin Li,1 Meng Zhao,2 Jing Du,1 Xiaodan Wang1,3 1Department of Geriatric Nephrology, 2Department of Clinical Data Repository

Earlier nephrology consultation may not be associated with improved short-term survival of acute kidney injury in very elderly men

Earlier nephrology consultation may not be associated with improved short-term survival of acute kidney injury in very elderly men Qinglin Li,1 Meng Zhao,2 Jing Du,1 Xiaodan Wang1 1Department of

Regulation of hematopoietic stem cells in the niche

Hematopoiesis provides a suitable model for understanding adult stem cells and their niche. Hematopoietic stem cells (HSCs) continuously produce blood cells through orchestrated proliferation, self-renewal, and differentiation in the bone marrow (BM). Within the BM exists a highly organized microenvironment termed “niche” where stem cells reside and are maintained. HSC niche is...

CAMKs support development of acute myeloid leukemia

We recently identified the human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse ortholog-paired Ig-like receptor (PirB) as receptors for several angiopoietin-like proteins (Angptls). We also demonstrated that PirB is important for the development of acute myeloid leukemia (AML), but exactly how an inhibitory receptor such as PirB can support cancer development...

Benefits of Levothyroxine Replacement Therapy on Nonalcoholic Fatty Liver Disease in Subclinical Hypothyroidism Patients

Objectives. To evaluate the effect of levothyroxine (LT4) replacement therapy on nonalcoholic fatty liver disease (NAFLD) in subclinical hypothyroidism (SCH) patients. Methods. This study was a post hoc analysis of a randomized controlled trial and involved 33 significant and 330 mild SCH patients. All of the significant SCH patients received LT4 supplement. The mild SCH patients...

The Role of a Single Angiogenesis Inhibitor in the Treatment of Recurrent Glioblastoma Multiforme: A Meta-Analysis and Systematic Review

Background Currently, the standard treatment for newly diagnosed glioblastoma multiforme (GBM) is maximal safe surgical resection followed by radiation therapy with concurrent and adjuvant temozolomide. However, disease recurs in almost all patients, and the optimal salvage treatment for recurrent GBM remains unclear. We conducted a systematic review and meta-analysis of...

Automatic screening of cervical cells using block image processing

Background Cervical cancer is the second leading cause of female-specific cancer-related deaths after breast cancer, especially in developing countries. However, the incidence of the disease may be significantly decreased if the patient is diagnosed in the pre-cancerous lesion stage or earlier. In recent years, computer-based algorithms are widely used in cervical cancer...

Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

, Hangzhou 310058, ChinaLinrong Lu AuthorsSearch for Jingjing Liang in:Nature Research journals • PubMed • Google ScholarSearch for Jun Lyu in:Nature Research journals • PubMed • Google ScholarSearch for Meng ... Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Dan Li in:Nature Research journals • PubMed • Google ScholarSearch for Mingzhu Zheng in:Nature Research journals • PubMed • Google

Robust Tube-Based MPC with Piecewise Affine Control Laws

2014 Academic Editor: Józef Banaś Copyright © 2014 Meng Zhao and Xiaoming Tang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted

Effects of Herb-Partitioned Moxibustion on the miRNA Expression Profiles in Colon from Rats with DSS-Induced Ulcerative Colitis

, Yan Huang, Hong-sheng Dong, Ji-meng Zhao, and Chuan-zi Dou established the animal model and performed the molecular experiments. Yan Huang, Zhe Ma, Yun-hua Cui, and Hui-rong Liu analyzed the data. Yan

A Generalized Minimum Cost Flow Model for Multiple Emergency Flow Routing

During real-life disasters, that is, earthquakes, floods, terrorist attacks, and other unexpected events, emergency evacuation and rescue are two primary operations that can save the lives and property of the affected population. It is unavoidable that evacuation flow and rescue flow will conflict with each other on the same spatial road network and within the same time window...

NERF encodes a RING E3 ligase important for drought resistance and enhances the expression of its antisense gene NFYA5 in Arabidopsis

NFYA5 is an important drought-stress inducible transcription factor gene that is targeted by miR169 in Arabidopsis. We show here that the cis-natural antisense transcript gene of NFYA5, NFYA5 Enhancing RING FINGER (NERF), can produce siRNAs from their overlapping region (OR) and affect NFYA5 transcripts by functioning together with miR169. The NERF protein functions as an E3...

Dyslipidemia in rural areas of North China: prevalence, characteristics, and predictive value

Background The prevalence of cardiovascular disease has been increasing worldwide. As a common pathogenic risk factor, dyslipidemia played a great role in the incidence and progress of these diseases. We investigated to achieve accurate and up-to-date information on the prevalence of dyslipidemia and its associations with other lipid-related diseases in rural North China. Methods...

Oscillating primary transcripts harbor miRNAs with circadian functions

. Author information AffiliationsCAS-MPG Partner Institute for Computational Biology, Shanghai 200031, ChinaHaifang Wang, Zenghua Fan, Meng Zhao, Juan Li & Jun YanInstitute of Neuroscience, CAS Center for ... Excellence in Brain Science and Intelligence Technology, Shanghai 200031, ChinaHaifang Wang, Meng Zhao & Jun YanInstitute for Biochemistry and Cell Biology, Shanghai 200031, ChinaMinghua Lu & Mofang

Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation

Hiwi is well known for its role in stem cell renewal, maintaining the resting stage, and downregulating cell cycle of stem cells via RNA silencing. And Hiwi overexpression has been recognized in several types of cancers. In the present study, we examined the Hiwi expression in colorectal cancer (CRC) specimens in both mRNA and protein levels via real-time quantitative PCR...

Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N9-Methyl Group in the Conformation and Bioactivity

One new cyclic hexapeptide named rubipodanin A (1), which is the first identified natural N-desmonomethyl Rubiaceae-type cyclopeptide, together with six known Rubiaceae-type cyclopeptides (2–7) were obtained using the TLC cyclopeptide protosite detection method with ninhydrin from the roots and rhizomes of Rubia podantha. The cyclopeptide structures were elucidated by extensive...