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Long-Term Effectiveness, Safety and Mortality Associated with the Use of TC-325 for Malignancy-Related Upper Gastrointestinal Bleeds: A Multicentre Retrospective Study

Malignant-related upper gastrointestinal bleeding (MRUGIB) is difficult to treat by conventional endoscopic methods. We sought to determine the efficacy, safety and mortality associated with the use of TC-325 for the treatment of MUGIB.

C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis

study. Supporting information S1 Appendix. The sequences of all 47 aptamers. (XLSX) 14 / 17 Author Contributions Data curation: Meng Zhao, Weibin Li. Formal analysis: Weibin Li, Kuancan Liu. Funding ... acquisition: Xiaopeng Lan. Methodology: Meng Zhao. Project administration: Xiaopeng Lan. Resources: Weibin Li, Huiling Li. Software: Kuancan Liu. Validation: Huiling Li. Writing ? original draft: Meng

AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria

AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria Qinglin Li,1 Meng Zhao,2

A Method Adjusting Consistency and Consensus for Group Decision-Making Problems with Hesitant Fuzzy Linguistic Preference Relations Based on Discrete Fuzzy Numbers

Management and Economics, Tianjin University, 300072, China 4School of Public Affairs, Zhejiang University, Hangzhou 310058, China Correspondence should be addressed to Meng Zhao; moc.361@8002705gnemgnin ... Received 25 December 2017; Accepted 23 May 2018; Published 12 July 2018 Academic Editor: Danilo Comminiello Copyright © 2018 Meng Zhao et al. This is an open access article distributed under the Creative

INSTITUTIONAL ENVIRONMENT AND INSTITUTIONAL INNOVATION IN SOCIAL ENTREPRENEURSHIP: EVIDENCE FROM THE INVESTMENTS OF EUROPEAN VENTURE PHILANTHROPY FUNDS (SUMMARY)

School of Management SKOLKOVO 2 University of Western Ontario 3 CONTACT: Rongdong Chen 4 Rongdong Chen, University of Western Ontario, Canada Meng Zhao, Moscow School of Management SKOLKOVO , Russia

The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat

Liu, Feng Yang, Meng Zhao, Lina Ma and Haijun Li contributed equally. AffiliationsCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, ChinaZhihong Liu, Feng Yang, Meng ... • Google Scholar Search for Meng Zhao in:Nature Research journals • PubMed • Google Scholar Search for Lina Ma in:Nature Research journals • PubMed • Google Scholar Search for Haijun Li in:Nature Research

The Role of Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Background. Acute exacerbation of IPF (AE-IPF) is associated with high mortality. We studied changes in pathogen involvement during AE-IPF and explored a possible role of infection in AE-IPF. Objectives. Our purpose is to investigate the role of infection in AE-IPF. Methods. Overall, we recruited 170 IPF patients (48 AE-IPF, 122 stable) and 70 controls at Shanghai Pulmonary...

Combined small RNA and gene expression analysis revealed roles of miRNAs in maize response to rice black-streaked dwarf virus infection

Sciences, Jinan, 250100, PR ChinaZhaodong Meng & Meng Zhao AuthorsSearch for Aiqin Li in:Nature Research journals • PubMed • Google Scholar Search for Guanghui Li in:Nature Research journals • PubMed ... • Google Scholar Search for Yuhan Zhao in:Nature Research journals • PubMed • Google Scholar Search for Zhaodong Meng in:Nature Research journals • PubMed • Google Scholar Search for Meng Zhao in:Nature

Menin Modulates Mammary Epithelial Cell Numbers in Bovine Mammary Glands Through Cyclin D1

Menin, the protein encoded by the MEN1 gene, is abundantly expressed in the epithelial cells of mammary glands. Here, we found MEN1/menin expression slowly decreased with advancing lactation but increased by the end of lactation. It happened that the number of bovine mammary epithelial cells decreases since lactation, suggesting a role of menin in the control of mammary...

Outcomes of renal function in elderly patients with acute kidney injury

Outcomes of renal function in elderly patients with acute kidney injury Qinglin Li,1 Meng Zhao,2 Jing Du,1 Xiaodan Wang1,3 1Department of Geriatric Nephrology, 2Department of Clinical Data Repository

Earlier nephrology consultation may not be associated with improved short-term survival of acute kidney injury in very elderly men

Earlier nephrology consultation may not be associated with improved short-term survival of acute kidney injury in very elderly men Qinglin Li,1 Meng Zhao,2 Jing Du,1 Xiaodan Wang1 1Department of

Regulation of hematopoietic stem cells in the niche

Hematopoiesis provides a suitable model for understanding adult stem cells and their niche. Hematopoietic stem cells (HSCs) continuously produce blood cells through orchestrated proliferation, self-renewal, and differentiation in the bone marrow (BM). Within the BM exists a highly organized microenvironment termed “niche” where stem cells reside and are maintained. HSC niche is...

CAMKs support development of acute myeloid leukemia

We recently identified the human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse ortholog-paired Ig-like receptor (PirB) as receptors for several angiopoietin-like proteins (Angptls). We also demonstrated that PirB is important for the development of acute myeloid leukemia (AML), but exactly how an inhibitory receptor such as PirB can support cancer development...

Intravenous injection of allogeneic umbilical cord-derived multipotent mesenchymal stromal cells reduces the infarct area and ameliorates cardiac function in a porcine model of acute myocardial infarction

BackgroundMultipotent mesenchymal stromal cell (MSC) therapy has been widely recognized as a feasible strategy for regenerating injured myocardial tissue. However, little is known about the efficacy of intravenous injection of allogeneic umbilical cord (UC) MSCs in preclinical models of porcine myocardial infarction.MethodsDifferent dosages of allogeneic UC-MSCs or the vehicle...

Benefits of Levothyroxine Replacement Therapy on Nonalcoholic Fatty Liver Disease in Subclinical Hypothyroidism Patients

Objectives. To evaluate the effect of levothyroxine (LT4) replacement therapy on nonalcoholic fatty liver disease (NAFLD) in subclinical hypothyroidism (SCH) patients. Methods. This study was a post hoc analysis of a randomized controlled trial and involved 33 significant and 330 mild SCH patients. All of the significant SCH patients received LT4 supplement. The mild SCH patients...

The Role of a Single Angiogenesis Inhibitor in the Treatment of Recurrent Glioblastoma Multiforme: A Meta-Analysis and Systematic Review

Background Currently, the standard treatment for newly diagnosed glioblastoma multiforme (GBM) is maximal safe surgical resection followed by radiation therapy with concurrent and adjuvant temozolomide. However, disease recurs in almost all patients, and the optimal salvage treatment for recurrent GBM remains unclear. We conducted a systematic review and meta-analysis of...

The Role of the Notch Signal Pathway in Mucosal Cell Metaplasia in Mouse Acute Otitis Media

, Meng Zhao and Xin-wei Wang photographed and processed the figures, Xiang Liu and Dong-Dong Ren wrote the manuscript, Jing Wang and Fang-Lu Chi revised the manuscript. Xiang Liu and Ning Cong contributed