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Tracheal tubes lubricated with water to reduce sore throat after intubation: A randomized non-inferiority trial

: Sang Gyu Kwak. Formal analysis: Sang Gyu Kwak. Investigation: Eugene Kim, Seong Mi Yang, Seoyeong Park, Jae-Hyon Bahk, Jeong-Hwa Seo. Methodology: Sang Gyu Kwak, Seoyeong Park, Jeong-Hwa Seo. Writing ... ± original draft: Eugene Kim, Seong Mi Yang, Seoyeong Park, Jeong-Hwa Seo. Writing ± review & editing: Eugene Kim, Seong Mi Yang, Sang Gyu Kwak, Jae-Hyon Bahk, Jeong-Hwa Seo. 10 / 12 11 / 12 1. Conway CM

Excessive remifentanil during total intravenous anesthesia is associated with increased risk of pain after robotic thyroid surgery

. Validation: Hyung-Chul Lee. Writing – original draft: Hyung-Chul Lee, Ho-Geol Ryu, Hyung-Jun Kim, Yoonsang Park, Soo Bin Yoon, Seong Mi Yang. Writing – review & editing: Hye-Won Oh, Chul-Woo Jung. 10 / 11

Linking drug target and pathway activation for effective therapy using multi-task learning

Despite the abundance of large-scale molecular and drug-response data, the insights gained about the mechanisms underlying treatment efficacy in cancer has been in general limited. Machine learning algorithms applied to those datasets most often are used to provide predictions without interpretation, or reveal single drug-gene association and fail to derive robust insights. We...

Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

Whether sensory nerve can sense bone density or metabolic activity to control bone homeostasis is unknown. Here we found prostaglandin E2 (PGE2) secreted by osteoblastic cells activates PGE2 receptor 4 (EP4) in sensory nerves to regulate bone formation by inhibiting sympathetic activity through the central nervous system. PGE2 secreted by osteoblasts increases when bone density...

The Effects of Music Intervention on Functional Connectivity Strength of the Brain in Schizophrenia

; nc.ude.ctseu@oulgnehc Mi Yang and Hui He contributed equally to this work. Received 20 August 2017; Revised 18 January 2018; Accepted 25 February 2018; Published 2 May 2018 Academic Editor: J. Michael Wyss ... Copyright © 2018 Mi Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

The Effects of Music Intervention on Functional Connectivity Strength of the Brain in Schizophrenia

; nc.ude.ctseu@oulgnehc Mi Yang and Hui He contributed equally to this work. Received 20 August 2017; Revised 18 January 2018; Accepted 25 February 2018; Published 2 May 2018 Academic Editor: J. Michael Wyss ... Copyright © 2018 Mi Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Role of clusterin/progranulin in toluene diisocyanate-induced occupational asthma

Toluene diisocyanate (TDI) exposure induces oxidative stress and epithelial cell-derived inflammation, which affect the pathogenesis of TDI-induced occupational asthma (TDI-OA). Recent studies suggested a role for clusterin (CLU) and progranulin (PGRN) in oxidative stress-mediated airway inflammation. To evaluate CLU and PGRN involvement in airway inflammation in TDI-OA, we...

Looking beyond the cancer cell for effective drug combinations

Combinations of therapies are being actively pursued to expand therapeutic options and deal with cancer’s pervasive resistance to treatment. Research efforts to discover effective combination treatments have focused on drugs targeting intracellular processes of the cancer cells and in particular on small molecules that target aberrant kinases. Accordingly, most of the...

Improvement in Left Ventricular Function with Intracoronary Mesenchymal Stem Cell Therapy in a Patient with Anterior Wall ST-Segment Elevation Myocardial Infarction

Background/AimsThe progression and development of congestive heart failure is still considered a large problem despite the existence of revascularization therapies and optimal, state-of-the-art medical services. An acute myocardial infarction (AMI) is a major cause of congestive heart failure, so researchers are investigating techniques to complement primary percutaneous coronary...

Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease

N-terminal prohormone of brain natriuretic peptide (NT-proBNP) was recently reported as a biomarker for diagnosing Kawasaki disease (KD). The basal NT-proBNP level, however, gradually decreases with age. We investigated the usefulness of an age-stratified cutoff value of NT-proBNP for diagnosing KD. All the patients enrolled in this study visited Chonnam National University...

A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of Asthmatics

Interest The authors have no conflict of interest to declare. Authors’ Contributions Sailesh Palikhe and Eun-Mi Yang performed the experiments. Udval Uuganbayar and Hoang Kim Tu Trinh performed the

A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of Asthmatics

authors have no conflict of interest to declare. Authors? Contributions Sailesh Palikhe and Eun-Mi Yang performed the experiments. Udval Uuganbayar and Hoang Kim Tu Trinh performed the statistical

Gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment

Gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment Zhen Zhang,1 Hanqing Qian,2 Mi Yang,2 Rutian Li,2 Jing Hu,1 Li Li,1 Lixia Yu,2 Baorui Liu,1,2 Xiaoping Qian1,2

Bacterial synthesis of N-hydroxycinnamoyl phenethylamines and tyramines

Background Hydroxycinnamic acids (HCAs) including cinnamic acid, p-coumaric acid, caffeic acid, and ferulic acid, are C6–C3 phenolic compounds that are synthesized via the phenylpropanoid pathway. HCAs serve as precursors for the synthesis of lignins, flavonoids, anthocyanins, stilbenes and other phenolic compounds. HCAs can also be conjugated with diverse compounds including...

Prediction of biological behavior and prognosis of colorectal cancer patients by tumor MSI/MMR in the Chinese population

Prediction of biological behavior and prognosis of colorectal cancer patients by tumor MSI/MMR in the Chinese population Wen-Yue Yan,1,* Jing Hu,1,2,* Li Xie,2 Lei Cheng,2 Mi Yang,2 Li Li,2 Jiong Shi

Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency

, Yang Yang, Mi Yang, Baorui LiuComprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, People’s Republic of

Biological synthesis of coumarins in Escherichia coli

Background Coumarins are a major group of plant secondary metabolites that serves as defense compounds against pathogens. Although coumarins can be obtained from diverse plant sources, the use of microorganisms to synthesize them could be an alternative way to supply building blocks for the synthesis of diverse coumarin derivatives. Results Constructs harboring two genes, F6′H...

Suppression of Specular Reflections by Metasurface with Engineered Nonuniform Distribution of Reflection Phase

, Air Force Early Warning Academy, Wuhan 430019, China Received 9 November 2014; Accepted 8 January 2015 Academic Editor: Sanming Hu Copyright © 2015 Xin Mi Yang et al. This is an open access article

Suppression of Specular Reflections by Metasurface with Engineered Nonuniform Distribution of Reflection Phase

, Air Force Early Warning Academy, Wuhan 430019, China Received 9 November 2014; Accepted 8 January 2015 Academic Editor: Sanming Hu Copyright © 2015 Xin Mi Yang et al. This is an open access article