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Search: authors:"Michael B. Hovater"

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Optimizing combination therapy in the management of hypertension: the role of the aliskiren, amlodipine, and hydrochlorothiazide fixed combination

Optimizing combination therapy in the management of hypertension: the role of the aliskiren, amlodipine, and hydrochlorothiazide fixed combination Michael B Hovater,1 Edgar A Jaimes1,2 1Division of

Purinergic signaling in the lumen of a normal nephron and in remodeled PKD encapsulated cysts

The nephron is the functional unit of the kidney. Blood and plasma are continually filtered within the glomeruli that begin each nephron. Adenosine 5′ triphosphate (ATP) and its metabolites are freely filtered by each glomerulus and enter the lumen of each nephron beginning at the proximal convoluted tubule (PCT). Flow rate, osmolality, and other mechanical or chemical stimuli...

Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals

Michael B. Hovater Dragos Olteanu Elizabeth L. Hanson Nai-Lin Cheng Brian Siroky Attila Fintha Peter Komlosi Wen Liu Lisa M. Satlin P. Darwin Bell Bradley K. Yoder Erik M. Schwiebert 0 ) Departments