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Outcomes in 1096 patients with severe thrombotic thrombocytopenic purpura before the Caplacizumab era

. Author Contributions Conceptualization: Andry Van de Louw, Eric Mariotte, Michael Darmon, Austin Cohrs, Douglas Leslie, Elie Azoulay. Data curation: Austin Cohrs. Formal analysis: Andry Van de Louw ... , Eric Mariotte, Michael Darmon, Elie Azoulay. 10 / 14 Funding acquisition: Andry Van de Louw, Douglas Leslie. Investigation: Andry Van de Louw. Methodology: Andry Van de Louw, Eric Mariotte, Michael

Corticosteroids for severe acute exacerbations of chronic obstructive pulmonary disease in intensive care: From the French OUTCOMEREA cohort

Nicolas Terzi 0 4 Ste´ phane Ruckly 4 Maït e´ Garrouste-OrgeasID 4 Yves Cohen 4 Vivien Hong Tuan HaID 4 Marc GainnierID 3 4 Shidasp Siami 4 Claire Dupuis 4 Michael Darmon 4 Elie Azoulay 4 Jean-Marie Forel 4 ... , Yves Cohen, Vivien Hong Tuan Ha, Marc Gainnier, Shidasp Siami, Claire Dupuis, Michael Darmon, Elie Azoulay, Jean-Marie Forel, Florian Sigaud, Christophe Adrie, Dany Goldgran-Toledano, Alexis Ferre

ICU strain and outcome in COVID-19 patients—A multicenter retrospective observational study

, Michael Darmon. 11 / 14 Data curation: Alexandre Demoule, Guillaume Louis, Safaa Nemlaghi, Edouard Jullien, Cyrielle Desnos, Sebastien Clerc, Elise Yvin, Nouchan Mellati, Cyril Charron, Guillaume ... Voiriot, Yoann Picard, Michael Darmon. Formal analysis: Alexandre Demoule, Guillaume Louis, Safaa Nemlaghi, Edouard Jullien, Cyrielle Desnos, Cyril Charron, Antoine Vieillard-Baron, Michael Darmon

Coagulation disorders in patients with severe hemophagocytic lymphohistiocytosis

Jacques Tudesq, Anne-Claire Lepretre, Eric Mariotte. Formal analysis: Michael Darmon. Investigation: Sandrine Valade. Methodology: Sandrine Valade, Be´rangère S. Joly, Agnès Veyradier, Ame´lie Launois

Increased mortality in patients with severe SARS-CoV-2 infection admitted within seven days of disease onset

Coronavirus disease 2019 (COVID-19) is creating an unprecedented healthcare crisis. Understanding the determinants of mortality is crucial to optimise intensive care unit (ICU) resource use and to identify targets for improving survival. In a multicentre retrospective study, we included 379 COVID-19 patients admitted to four ICUs between 20 February and 24 April 2020 and...

Bedside Doppler ultrasound for the assessment of renal perfusion in the ICU: advantages and limitations of the available techniques

Michael Darmon 0 1 0 Jacques Lisfranc Medical School, Jean Monnet University , Saint-Etienne , France 1 Medical-Surgical Intensive Care Unit, Saint-Etienne University Hospital , Avenue Albert Raimond

Bedside Doppler ultrasound for the assessment of renal perfusion in the ICU: advantages and limitations of the available techniques

Three Doppler-derived techniques have been proposed to assess renal perfusion at bedside: Doppler-based renal resistive index (RI) which has been extensively but imperfectly studied in assessing renal allograft status and changes in renal perfusion in critically ill patients and for predicting the reversibility of an acute kidney injury (AKI), semi-quantitative evaluation of...

Candidemia in critically ill immunocompromised patients: report of a retrospective multicenter cohort study

BackgroundImmunocompromised critically ill patients constitute a population with the high risk of candidemia. This retrospective study aimed to assess the outcome of immunocompromised critically ill patients with candidemia. Secondary objectives were to describe clinical phenotypes of these patients, Candida ecology, and factors associated with mortality.ResultsOverall, 121...

Clinical and biological clusters of sepsis patients using hierarchical clustering

, Paris, France); Michael Darmon (Medical ICU, Saint Etienne University Hospital, St Etienne, France); and Christophe Clec’h (ICU, Avicenne Hospital, Bobigny, and UMR 1137 Inserm– Paris Diderot university ... , France); Martin Cour Medial ICU, Edouard Heriot hospital, Lyon France), Michael Darmon (ICU, Saint Etienne Hospital, Saint Etienne, France); Etienne de Montmollin (ICU, Delafontaine Hospital, Saint Denis