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Search: authors:"Michael L. Goodson"

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Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals

The NCoR-1 and NCoR-2 corepressors are products of an early gene duplication near the beginning of vertebrate evolution and play both overlapping and divergent roles in development and physiology. Alternative-splicing of NCoR-1 and NCoR-2 further customizes their functions. To better understand the evolutionary basis of this phenomenon we extended our prior study of NCoR-1 and...