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8 papers found.
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Prescription of secondary preventive drugs after ischemic stroke: results from the Malaysian National Stroke Registry

Evaluation of secondary stroke prevention in low and middle-income countries remains limited. This study assessed the prescription of secondary preventive drugs among ischemic stroke patients upon hospital discharge in Malaysia and identified factors related to the prescribing decisions. From Malaysian National Stroke Registry, we included patients with non-fatal ischemic stroke...

Use of a Diagnostic Score to Prioritize Computed Tomographic (CT) Imaging for Patients Suspected of Ischemic Stroke Who May Benefit from Thrombolytic Therapy

Background A shortage of computed tomographic (CT) machines in low and middle income countries often results in delayed CT imaging for patients suspected of a stroke. Yet, time constraint is one of the most important aspects for patients with an ischemic stroke to benefit from thrombolytic therapy. We set out to assess whether application of the Siriraj Stroke Score is able to...

Use of Antihypertensive Drugs and Ischemic Stroke Severity – Is There a Role for Angiotensin-II?

Background The increase in angiotensin II (Ang II) formation by selected antihypertensive drugs is said to exhibit neuroprotective properties, but this translation into improvement in clinical outcomes has been inconclusive. We undertook a study to investigate the relationship between types of antihypertensive drugs used prior to a stroke event and ischemic stroke severity. We...

Identification of effective screening strategies for cardiovascular disease prevention in a developing country: using cardiovascular risk-estimation and risk-reduction tools for policy recommendations

Background Recent increases in cardiovascular risk-factor prevalences have led to new national policy recommendations of universal screening for primary prevention of cardiovascular disease in Malaysia. This study assessed whether the current national policy recommendation of universal screening was optimal, by comparing the effectiveness and impact of various cardiovascular...

Cardiovascular risk factor treatment targets and renal complications in high risk vascular patients: a cohort study

Sharmini Selvarajah 0 Yolanda vD Graaf Frank LJ Visseren Michiel L Bots for the SMART study group 0 Clinical Research Centre, Kuala Lumpur Hospital , Kuala Lumpur , Malaysia Background: To

An Asian Validation of the TIMI Risk Score for ST-Segment Elevation Myocardial Infarction

Background Risk stratification in ST-elevation myocardial infarction (STEMI) is important, such that the most resource intensive strategy is used to achieve the greatest clinical benefit. This is essential in developing countries with wide variation in health care facilities, scarce resources and increasing burden of cardiovascular diseases. This study sought to validate the...

Clustering of cardiovascular risk factors and carotid intima-media thickness: The USE-IMT study

Background The relation of a single risk factor with atherosclerosis is established. Clinically we know of risk factor clustering within individuals. Yet, studies into the magnitude of the relation of risk factor clusters with atherosclerosis are limited. Here, we assessed that relation. Methods Individual participant data from 14 cohorts, involving 59,025 individuals were used...

Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events

. Stehouwer 0 Michiel L. Bots 0 Hester M. den Ruijter 0 0 Editor: Cristian Apetrei, University of Pittsburgh Center for Vaccine Research, UNITED STATES ☯ These authors contributed equally to this work