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ID1-induced p16/IL6 axis activation contributes to the resistant of hepatocellular carcinoma cells to sorafenib

, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong, ChinaLei-lei Niu, Ming-Yue Li, Sheng-li Yang, Bao-guang Hu, Charing C. N. Chong, Jianwei Ren ... Lei-lei Niu in:Nature Research journals • PubMed • Google Scholar Search for Chuan-le Cheng in:Nature Research journals • PubMed • Google Scholar Search for Ming-Yue Li in:Nature Research journals

Impact of meteorological factors on the incidence of bacillary dysentery in Beijing, China: A time series analysis (1970-2012)

. Writing ± review & editing: Long Yan, Hong Wang, Xuan Zhang, Ming-Yue Li, Juan He. 12 / 13 1. Niyogi SK . Shigellosis. Journal of microbiology (Seoul , Korea). 2005 ; 43 ( 2 ): 133 ± 43 . Epub 2005/05/10

The relationship between human leukocyte antigen-DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population

Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationship of HLA-DP rs9277535 and HLA-DQ rs7453920 with the outcomes of HCV infection. The rs9277535 and rs7453920 were genotyped in 370 subjects with chronic HCV infection, 194...

The relationship between human leukocyte antigen-DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population

Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationship of HLA-DP rs9277535 and HLA-DQ rs7453920 with the outcomes of HCV infection. The rs9277535 and rs7453920 were genotyped in 370 subjects with chronic HCV infection, 194...

PedAM: a database for Pediatric Disease Annotation and Medicine

There is a significant number of children around the world suffering from the consequence of the misdiagnosis and ineffective treatment for various diseases. To facilitate the precision medicine in pediatrics, a database namely the Pediatric Disease Annotations & Medicines (PedAM) has been built to standardize and classify pediatric diseases. The PedAM integrates both biomedical...

eRAM: encyclopedia of rare disease annotations for precision medicine

Rare diseases affect over a hundred million people worldwide, most of these patients are not accurately diagnosed and effectively treated. The limited knowledge of rare diseases forms the biggest obstacle for improving their treatment. Detailed clinical phenotyping is considered as a keystone of deciphering genes and realizing the precision medicine for rare diseases. Here, we...

Baicalein prevents 6-OHDA/ascorbic acid-induced calcium-dependent dopaminergic neuronal cell death

Medical Sciences, University of Macau, Taipa, Macao SAR, ChinaSheng-Fang Wang, Ming-Yue Wu, Cui-Zan Cai, Huanxing Su & Jia-Hong LuSchool of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong ... AuthorsSearch for Sheng-Fang Wang in:Nature Research journals • PubMed • Google Scholar Search for Liang-Feng Liu in:Nature Research journals • PubMed • Google Scholar Search for Ming-Yue Wu in:Nature Research

RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia

• PubMed • Google Scholar Search for Yuan Li in:Nature Research journals • PubMed • Google Scholar Search for Adam Cloe in:Nature Research journals • PubMed • Google Scholar Search for Ming Yue in:Nature ... information Author notes These authors contributed equally: Li Chen, Yuan Li. AffiliationsDepartment of Pathology, University of Chicago, Chicago, IL, 60637, USAJason X. Cheng, Li Chen, Yuan Li, Adam Cloe, Ming

Genetic variants in interferon-λ 4 influences HCV clearance in Chinese Han population

Recent many studies indicated a novel dinucleotide variant in ss469415590 (TT vs. ΔG) of interferon-λ 4 (IFNL4) gene strongly associated with hepatitis C virus clearance. To evaluate the impact and clinical usefulness of IFNL4 ss469415590 genotype on predicting both spontaneous HCV clearance and response to therapy in Chinese population, we genotyped 795 chronic HCV carriers, 460...

Efficacy differences of electroacupuncture with single acupoint or matching acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial

Previous studies have shown that acupuncture is beneficial for the alleviation of chemotherapy-induced nausea and vomiting. However, there is a lack of clinical evidence concerning the effects of acupoint-matching on chemotherapy-induced nausea and vomiting. This is a parallel randomized controlled trial to evaluate the occurrence of nausea and vomiting after chemotherapy (the...

Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis

conflict of interests. Authors’ Contributions Rongbin Yu and Peng Huang participated in the design of the study. Yinan Yao, Ming Yue, Mei Liu, and Feng Zang took charge of data collection and quality control ... . Yinan Yao, Jie Wang, and Hongbo Chen performed the statistical analysis. Jun Li and Yun Zhang contributed materials and analysis tools. Yinan Yao, Ming Yue, and Peng Huang wrote the paper. All authors

Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis

conflict of interests. Authors’ Contributions Rongbin Yu and Peng Huang participated in the design of the study. Yinan Yao, Ming Yue, Mei Liu, and Feng Zang took charge of data collection and quality control ... . Yinan Yao, Jie Wang, and Hongbo Chen performed the statistical analysis. Jun Li and Yun Zhang contributed materials and analysis tools. Yinan Yao, Ming Yue, and Peng Huang wrote the paper. All authors

Evaluation of the mechanisms of intron loss and gain in the social amoebae Dictyostelium

Background Spliceosomal introns are a common feature of eukaryotic genomes. To approach a comprehensive understanding of intron evolution on Earth, studies should look beyond repeatedly studied groups such as animals, plants, and fungi. The slime mold Dictyostelium belongs to a supergroup of eukaryotes not covered in previous studies. Results We found 441 precise intron losses in...

The Invasion of Coastal Areas in South China by Ipomoea cairica May Be Accelerated by the Ecotype Being More Locally Adapted to Salt Stress

Local adaptation and phenotypic plasticity are two alternative mechanisms used by invasive plants for range expansion. We conducted a series of experiments to investigate the role of these mechanisms in the recent expansion of the invasive Ipomoea cairica from non-saline to salt-stressed coastal habitats. A comparison of the plant’s photosynthetic traits and construction costs...

LincSNP 2.0: an updated database for linking disease-associated SNPs to human long non-coding RNAs and their TFBSs

We describe LincSNP 2.0 (http://bioinfo.hrbmu.edu.cn/LincSNP), an updated database that is used specifically to store and annotate disease-associated single nucleotide polymorphisms (SNPs) in human long non-coding RNAs (lncRNAs) and their transcription factor binding sites (TFBSs). In LincSNP 2.0, we have updated the database with more data and several new features, including (i...

Patterns of taxonomic, phylogenetic diversity during a long-term succession of forest on the Loess Plateau, China: insights into assembly process

, Northwest University, Taibai north Rd.229, Xi’an City, Shaanxi Province, ChinaYongfu Chai, Ming Yue, Xiao Liu, Yaoxin Guo, Mao Wang, Jinshi Xu, Chenguang Zhang, Yu Chen & Lixia ZhangPlant Ecology Department ... , University of Tuebingen, Auf der Morgenstelle 3, 72076 Tuebingen, GermanyRuichang Zhang AuthorsSearch for Yongfu Chai in:Nature Research journals • PubMed • Google ScholarSearch for Ming Yue in:Nature Research