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Canonical correlation analysis (CCA) of anthropometric parameters and physical activities with blood lipids

Anthropometric parameters and physical activities are significant factors influencing lipid levels, but few research have demonstrated the effect of amount of activities on lipid levels. Our research analyzed and explored this relationships. A multi-stage stratified sampling method was used to select the investigation subjects in Hubei, China. A questionnaire survey, physical...

USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization

Histone chaperone ASF1A has been reported to be dysregulated in multiple tumors; however, the underlying molecular mechanism that how the abundance and function of ASF1A are regulated remains unclear. Here we report that ASF1A is physically associated with USP52, which is previously identified as a pseudo-deubiquitinase. Interestingly, we demonstrate that USP52 is a bona fide...

Research progress of the role and mechanism of extracellular signal-regulated protein kinase 5 (ERK5) pathway in pathological pain

. Acknowledgements We sincerely thank Dr. Qing-he ZHOU (School of Medicine, Zhejiang University, China) for his guidance. Compliance with ethics guidelines Li-na YU, Li-hong SUN, Min WANG, and Min YAN declare that

Identification of Partitions in a Homogeneous Activity Group Using Mobile Devices

Yat-Sen University, Guangzhou 510006, China Received 5 January 2016; Accepted 31 March 2016 Academic Editor: Peter Brida Copyright © 2016 Na Yu et al. This is an open access article distributed

Identification of Partitions in a Homogeneous Activity Group Using Mobile Devices

Yat-Sen University, Guangzhou 510006, China Received 5 January 2016; Accepted 31 March 2016 Academic Editor: Peter Brida Copyright © 2016 Na Yu et al. This is an open access article distributed

Mild volume acute normovolemic hemodilution is associated with lower intraoperative transfusion and postoperative pulmonary infection in patients undergoing cardiac surgery -- a retrospective, propensity matching study

Background Perioperative allogenic transfusion is required in almost 50% of patients undergoing cardiac surgery and is associated with higher risk of mortality and morbidity (Xue et al., Lancet 387:1905, 2016; Ferraris et al., Ann Thorac Surg 91:944–82, 2011). Acute normovolemic hemodilution (ANH) is recommended as a potential strategy during cardiac surgery, but the blood...

Context-Aware Community Construction in Proximity-Based Mobile Networks

Received 28 August 2014; Accepted 1 September 2014 Academic Editor: David Taniar Copyright © 2015 Na Yu and Qi Han. This is an open access article distributed under the Creative Commons Attribution

Therapeutic effects of histone deacetylase inhibitors in a murine asthma model

Objective and design To investigate the therapeutic effects of various HDAC inhibitors on the development of chronic allergic airway disease in mice with airway inflammation, airway remodeling, and airway hyperresponsiveness. Subjects Wild-type BALB/C mice (N = 72). Treatment Tubastatin A HCl [TSA, a selective histone deacetylase 6 (HDAC6) inhibitor], PCI-34051 (a selective HDAC8...

A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block

Midbrain dopamine neurons exhibit a novel type of bursting that we call “inverted square wave bursting” when exposed to Ca2+-activated small conductance (SK) K+ channel blockers in vitro. This type of bursting has three phases: hyperpolarized silence, spiking, and depolarization block. We find that two slow variables are required for this type of bursting, and we show that the...

Correction: Reference Ranges and Association of Age and Lifestyle Characteristics with Testosterone, Sex Hormone Binding Globulin, and Luteinizing Hormone among 1166 Western Chinese Men

Xubo Shen Ruifeng Wang Na Yu Yongjun Shi Honggang Li Chengliang Xiong Yan Li Ellen M. Wells Yuanzhong Zhou Fig 1 appears incorrectly in the published article. The first panel, ªPercent of men with low

Evaluation and simulation of nitrogen mineralization of paddy soils in Mollisols area of Northeast China under waterlogged incubation

Background Understanding the nitrogen (N) mineralization process and applying appropriate model simulation are key factors in evaluating N mineralization. However, there are few studies of the N mineralization characteristics of paddy soils in Mollisols area of Northeast China. Materials and methods The soils were sampled from the counties of Qingan and Huachuan, which were...

Reference Ranges and Association of Age and Lifestyle Characteristics with Testosterone, Sex Hormone Binding Globulin, and Luteinizing Hormone among 1166 Western Chinese Men

Decreased total testosterone (TT) is the recommended metric to identify age-related hypogonadism. However, average TT and the extent to which it varies by age, can vary substantially among different populations. Population-specific reference ranges are needed to understand normal versus abnormal TT levels. Therefore, the goal for this study was to describe androgen concentrations...

Anti-Diabetic Effects of Jiang Tang Xiao Ke Granule via PI3K/Akt Signalling Pathway in Type 2 Diabetes KKAy Mice

Jiang Tang Xiao Ke (JTXK) granule, a Chinese herbal formula, has been used clinically to treat type 2 diabetes (T2DM) for decades. Our previous studies showed that JTXK granule exhibited anti-diabetic and anti-oxidative functions in experimental diabetic rats induced by a high fat diet and streptozotocin. However, the underlying mechanisms remain poorly understood. Herein, we...

Effects of Straw Return in Deep Soils with Urea Addition on the Soil Organic Carbon Fractions in a Semi-Arid Temperate Cornfield

Returning straw to deep soil layers by using a deep-ditching-ridge-ploughing method is an innovative management practice that improves soil quality by increasing the soil organic carbon (SOC) content. However, the optimum quantity of straw return has not been determined. To solve this practical production problem, the following treatments with different amounts of corn straw were...

A Computational Study of Spike Time Reliability in Two Types of Threshold Dynamics

Na Yu 0 Yue-Xian Li 0 Rachel Kuske 0 0 Present address: N. Yu Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center , New Orleans, LA 70112, USA Spike time

Stimulation-induced ectopicity and propagation windows in model damaged axons

Neural tissue injuries render voltage-gated Na+ channels (Nav) leaky, thereby altering excitability, disrupting propagation and causing neuropathic pain related ectopic activity. In both recombinant systems and native excitable membranes, membrane damage causes the kinetically-coupled activation and inactivation processes of Nav channels to undergo hyperpolarizing shifts. This...

USP9X regulates centrosome duplication and promotes breast carcinogenesis

Wang, Qi Zhang, Cheng Cao, Shuai Ma, Na Yu, Yan Wang, Yongfeng Shang & Lei ShiLaboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, ChinaXiang Ding & Fuquan ... • Google ScholarSearch for Na Yu in:Nature Research journals • PubMed • Google ScholarSearch for Fuquan Yang in:Nature Research journals • PubMed • Google ScholarSearch for Yan Wang in:Nature Research

Solubility Characteristics and Slow-Release Mechanism of Nitrogen from Organic-Inorganic Compound Coated Urea

A soil incubation method was used to investigate the solubility characteristics and slow-release mechanism of organic-inorganic compound coated urea at temperature of 10, 20, and 30°C. The membrane microstructure with and without incubation was tested via scanning electron microscopy (SEM). Slow release of nitrogen (N) from different inorganic minerals was analysed by the...