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108 papers found.
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The pervasive effects of timing of parental mental health disorders on adolescent deliberate self-harm risk

Contributions Conceptualization: Nan Hu, Catherine L. Taylor, Rebecca A. Glauert, Jianghong Li. Formal analysis: Nan Hu. 13 / 16 Funding acquisition: Catherine L. Taylor, Rebecca A. Glauert, Jianghong Li ... . Methodology: Nan Hu, Catherine L. Taylor, Rebecca A. Glauert, Jianghong Li. Project administration: Rebecca A. Glauert. Software: Rebecca A. Glauert. Supervision: Catherine L. Taylor, Rebecca A. Glauert

Interaction between CD177 and platelet endothelial cell adhesion molecule-1 downregulates membrane-bound proteinase-3 (PR3) expression on neutrophils and attenuates neutrophil activation induced by PR3-ANCA

A recent study found that CD177 served as a receptor of membrane-bound proteinase-3 (mPR3) in a subset of neutrophils. Furthermore, CD177 has been identified as a high-affinity heterophilic binding partner for the endothelial cell platelet endothelial cell adhesion molecule-1 (PECAM-1). The current study aimed to investigate whether the interaction between PECAM-1 and CD177 could...

Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog

Betulinic acid (BA) and its derivatives are a class of high-profile drug candidates, but their anticancer effects on resistant cancer have rarely been reported. Although a few studies indicated mitophagy is related with drug resistance, its role in different cancer types and anticancer agents treatment remains largely unclear. Here, we find that B5G1, a new derivative of BA...

The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways

Agricultural University (2016?2018). Author Contributions Xiao-jie Mi wrote the main manuscript text. Jin-gang Hou, Zi Wang and Shen Ren prepared Figures 1?7. Ye Han and Jun-nan Hu provided advices. Wei Li

Molecular characterization of mesenchymal stem cells in human osteoarthritis cartilage reveals contribution to the OA phenotype

). Author Contributions Chathuraka T. Jayasuriya: Conception and design, collection and assembly of data, data analysis and interpretation, manuscript writing, final approval of manuscript. Nan Hu

Propofol Protects Rat Cardiomyocytes from Anthracycline-Induced Apoptosis by Regulating MicroRNA-181a In Vitro and In Vivo

Xiaokun Wang,1,2,3 Nan Hu,1,2,3 Peng Zhou,1,2,3 and Kaiyuan Wang1,2,3 1Department of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer ... performed the experiments. Nan Hu and Peng Zhou reviewed and edited the manuscript for important intellectual content and gave final approval of the version to be published. Hongwei Zhao and Xiaobei Zhang

Significant Enhancement of MgZnO Metal-Semiconductor-Metal Photodetectors via Coupling with Pt Nanoparticle Surface Plasmons

Engineering, Changchun University of Science and Technology. Nan Hu is a graduate student in School of Materials Science and Engineering, Changchun University of Science and Technology. Xiaojiang Yang is a

Ammonium Bisphosphonate Polymeric Magnetic Nanocomplexes for Platinum Anticancer Drug Delivery and Imaging with Potential Hyperthermia and Temperature-Dependent Drug Release

Fellows,2 Nikorn Pothayee,3 Nan Hu,1 Nipon Pothayee,1 Ami Jo,1 Ana C. Bohórquez,4 Carlos Rinaldi,4 Olin Thompson Mefford,2 Richey M. Davis,1 and Judy S. Riffle1 1Department of Chemistry, Department of

Ammonium Bisphosphonate Polymeric Magnetic Nanocomplexes for Platinum Anticancer Drug Delivery and Imaging with Potential Hyperthermia and Temperature-Dependent Drug Release

Fellows,2 Nikorn Pothayee,3 Nan Hu,1 Nipon Pothayee,1 Ami Jo,1 Ana C. Bohórquez,4 Carlos Rinaldi,4 Olin Thompson Mefford,2 Richey M. Davis,1 and Judy S. Riffle1 1Department of Chemistry, Department of

Auxin Response Factors (ARFs) are potential mediators of auxin action in tomato response to biotic and abiotic stress (Solanum lycopersicum)

Gouiaa, Nan Hu. Investigation: Sarah Bouzroud, Sandra Gouiaa, Nan Hu. Methodology: Sarah Bouzroud, Sandra Gouiaa, Nan Hu, Isabelle Mila. Resources: Isabelle Mila. Supervision: Anne Bernadac, AbdelAziz

Restitution characteristics of His bundle and working myocardium in isolated rabbit hearts

. Dosdall. Formal analysis: Shangwei Huang, Jian Huang, Nuttanont Panitchob, Nan Hu, Derek J. Dosdall. Funding acquisition: Liqun Wu, Ravi Ranjan, Derek J. Dosdall. Investigation: Shangwei Huang, Jian ... Huang, Derek J. Dosdall. Methodology: Shangwei Huang, Jian Huang, Nuttanont Panitchob, Nan Hu, Derek J. Dosdall. Project administration: Derek J. Dosdall. Resources: Derek J. Dosdall. Software: Derek J

Up-regulation of calreticulin in mouse liver tissues after long-term irradiation with low-dose-rate gamma rays

Hydrometallurgy and Biological Research Institute. Author Contributions Conceptualization: Lan Yi, Nan Hu, Jie Yin. Data curation: Lan Yi. Formal analysis: Lan Yi. Funding acquisition: Lan Yi, Nan Hu, Dexin ... Ding. Project administration: Dexin Ding. Software: Lan Yi. Writing ± original draft: Lan Yi, Jing Sun, Hongxiang Mu, Keren Dai. Writing ± review & editing: Lan Yi, Nan Hu, Jing Sun, Hongxiang Mu. 12

The interfacial pH of acidic degradable polymeric biomaterials and its effects on osteoblast behavior

when p values were <0.05. 1 0 1 1 Author Contributions Changshun Ruan, Xinzhou Zhang and Haobo Pan conducted the design of the study and coordination. Changshun Ruan and Nan Hu carried out all the

A trehalase from Zunongwangia sp.: characterization and improving catalytic efficiency by directed evolution

Background Trehalases have potential applications in several fields, including food additives, insecticide development, and transgenic plant. In the present study, we focused on a trehalase from the marine bacterium Zunongwangia sp., which hydrolyzes trehalose to glucose. Results A novel gene, treZ (1590 bp) encoding an α, α-trehalase of 529 amino acids was cloned from...

Exploring the key genes and signaling transduction pathways related to the survival time of glioblastoma multiforme patients by a novel survival analysis model

This study is to explore the key genes and signaling transduction pathways related to the survival time of glioblastoma multiforme (GBM) patients. Our results not only showed that mutually explored GBM survival time related genes and signaling transduction pathways are closely related to the GBM, but also demonstrated that our innovated constrained optimization algorithm...

Characterization of a cold-active esterase from Serratia sp. and improvement of thermostability by directed evolution

Background In recent years, cold-active esterases have received increased attention due to their attractive properties for some industrial applications such as high catalytic activity at low temperatures. Results An esterase-encoding gene (estS, 909 bp) from Serratia sp. was identified, cloned and expressed in Escherichia coli DE3 (BL21). The estS encoded a protein (EstS) of 302...

Millimeter-Wave Microstrip Antenna Array Design and an Adaptive Algorithm for Future 5G Wireless Communication Systems

September 2016; Accepted 14 November 2016 Academic Editor: Atiqur Rahman Copyright © 2016 Cheng-Nan Hu et al. This is an open access article distributed under the Creative Commons Attribution License

Breast cancer risk factors and mammographic density among high-risk women in urban China

Kai Zhang Ni Li Shen Wang Luopei Wei Nan Hu Gretchen L. Gierach Min Dai Xiaohong R. Yang Jie He ARTICLE Elevated mammographic density (MD) is an established breast cancer risk factor. Studies examining

Primary Angle Closure and Sequence Variants within MicroRNA Binding Sites of Genes Involved in Eye Development

Purpose The formation of primary angle closure (PAC) and primary angle closure glaucoma (PACG) is regulated by a tissue remodeling pathway that plays a critical role in eye development. MicroRNAs (miRNAs) are powerful gene expression regulators and may exert their effects on tissue remodeling genes. This study investigated the associations between gene variants (single-nucleotide...