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35 papers found.
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Impact of mapped EQ-5D utilities on cost-effectiveness analysis: in the case of dialysis treatments

Nan Luo 0 JEL Classification I 0 0 Saw Swee Hock School of Public Health, National University of Singapore , Singapore, Singapore Objectives This study aimed to evaluate the performance of EQ-5D data

Valuation of the EQ-5D-5L in Taiwan

: Fang- Ju Lin, Jen-Yu Chang, Nan Luo, A. Simon Pickard. Funding acquisition: Hsiang-Wen Lin. Investigation: Chia-Ing Li, Nan Luo, Juan M. Ramos Go?i, Chao-Hsiun Tang, Chien-Ning Hsu. Project ... administration: Churn-Shiouh Gau. Resources: Hsiang-Wen Lin, Churn-Shiouh Gau, Chao-Hsiun Tang. Validation: Chia-Ing Li, Nan Luo, Chien-Ning Hsu. Visualization: Chia-Ing Li, Churn-Shiouh Gau, Nan Luo, A. Simon

Is EQ-5D-5L Better Than EQ-5D-3L? A Head-to-Head Comparison of Descriptive Systems and Value Sets from Seven Countries

. Janssen, Gouke J. Bonsel and Nan Luo) are members of the EuroQol Group. Data availability statement All data analysed in this study are stored at the central data archive of the EuroQol Research Foundation

Logical inconsistencies in time trade-off valuation of EQ-5D-5L health states: Whose fault is it?

. Author Contributions Data curation: Nan Luo. Formal analysis: Reinier Timman. Methodology: M. F. Janssen. Supervision: Jan van Busschbach. Writing ± original draft: Zhihao Yang. Writing ± review ... & editing: Jan van Busschbach, Nan Luo. 9 / 10 1. Herdman M , Gudex C , Lloyd A , Janssen M , Kind P , Parkin D , et al. ( 2011 ) Development and preliminary testing of the new five-level version of EQ-5D

Validation of Brunei’s Malay EQ-5D Questionnaire in Patients with Type 2 Diabetes

Background The Malay spoken in Brunei a South East Asian country where Malay is the national language is distinctive and different from Malay spoken in Malaysia, Singapore and Indonesia. This study aimed to develop a Brunei Malay version of the 5-level EQ-5D questionnaire (EQ-5D-5L) and to assess its psychometric properties among patients with type 2 diabetes mellitus (T2DM...

Mapping and direct valuation: do they give equivalent EQ-5D-5L index scores?

Objective Utility values of health states defined by health-related quality of life instruments can be derived from either direct valuation (‘valuation-derived’) or mapping (‘mapping-derived’). This study aimed to compare the utility-based EQ-5D-5L index scores derived from the two approaches as a means to validating the mapping function developed by van Hout et al for the EQ-5D...

EuroQol Protocols for Time Trade-Off Valuation of Health Outcomes

The time trade-off (TTO) valuation technique is widely used to determine utility values of health outcomes to inform quality-adjusted life-year (QALY) calculations for use in economic evaluation. Protocols for implementing TTO vary in aspects such as the trade-off framework, iteration procedure and its administration model and method, training of respondents and interviewers, and...

Mapping the Functional Assessment of Cancer Therapy - Breast (FACT-B) to the 5-level EuroQoL group’s 5-dimension questionnaire (EQ-5D-5L) utility index in a Multi-ethnic Asian population

Purpose To develop an algorithm for mapping the Functional Assessment of Cancer Therapy – Breast (FACT-B) to the 5-level EuroQoL Group’s 5-dimension questionnaire (EQ-5D-5L) utility index. Methods A survey of 238 breast cancer patients in Singapore was conducted. Models using various regression methods with or without recognizing the upper boundary of utility values at 1 were...

Quality of life and related factors of nursing home residents in Singapore

Background Litter is known about the well-being of nursing home (NH) residents in Singapore. This study aimed to identify predictors of self-reported quality of life (QOL) of NH residents in Singapore. Methods In face-to-face interviews, trained medical students assessed each consenting resident recruited from 6 local NHs using a modified Minnesota QOL questionnaire, and rating...

Image Quality and Stenosis Assessment of Non-Contrast-Enhanced 3-T Magnetic Resonance Angiography in Patients with Peripheral Artery Disease Compared with Contrast-Enhanced Magnetic Resonance Angiography and Digital Subtraction Angiography

Purpose To evaluate the diagnostic performance of flow-sensitive dephasing (FSD)-prepared steady-state free precession (SSFP) magnetic resonance angiography (MRA) at 3 T for imaging infragenual arteries relative to contrast-enhanced MRA (CE-MRA) and digital subtraction angiography (DSA). Materials and Methods A series of 16 consecutive patients with peripheral arterial disease...

Cross-cultural measurement equivalence of the 5-level EQ-5D (EQ-5D-5L) in patients with type 2 diabetes mellitus in Singapore

Background This study aimed to assess the measurement equivalence of the 5-level EQ-5D (EQ-5D-5L) among the English, Chinese, and Malay versions. Methods A convenience sample of patients with type 2 diabetes mellitus were enrolled from a public primary health care institution in Singapore. The survey questionnaire comprised the EQ-5D-5L and questions assessing participants’ socio...

A Novel Tracking Algorithm via Feature Points Matching

Visual target tracking is a primary task in many computer vision applications and has been widely studied in recent years. Among all the tracking methods, the mean shift algorithm has attracted extraordinary interest and been well developed in the past decade due to its excellent performance. However, it is still challenging for the color histogram based algorithms to deal with...

Hemodialysis versus Peritoneal Dialysis: A Comparison of Survival Outcomes in South-East Asian Patients with End-Stage Renal Disease

Background Studies comparing patient survival of hemodialysis (HD) and peritoneal dialysis (PD) have yielded conflicting results and no such study was from South-East Asia. This study aimed to compare the survival outcomes of patients with end-stage renal disease (ESRD) who started dialysis with HD and PD in Singapore. Methods Survival data for a maximum of 5 years from a single...

Do chronic disease patients value generic health states differently from individuals with no chronic disease? A case of a multicultural Asian population

Background There is conflicting evidence as to whether patients with chronic disease value hypothetical health states differently from individuals who have not experienced any long-lasting diseases. Furthermore, most studies regarding this issue have been conducted in western countries, with only one conducted in Asia. We aimed to evaluate possible systematic differences in the...

How is the most severe health state being valued by the general population?

Background It has been reported that valuation of health states that are close to death, such as the most severe health state, can be affected by health state valuation procedure, and their utility values are difficult to predict. We examined how the most severe health states of Short Form-6 dimension (SF-6D) and EuroQoL-5 dimension-3 level (EQ-5D-3L) were valued by the Singapore...

Quantitation of α-Lactalbumin by Liquid Chromatography Tandem Mass Spectrometry in Medicinal Adjuvant Lactose

Lactose is a widely used pharmaceutical excipient, sometimes irreplaceable. Traces of residual proteins left during production of lactose are potential allergen to body. The present paper describes a sensitive and specific LC-MS method for the determination of α-lactalbumin (α-La) in lactose samples. Chromatographic separation was performed on an Acquity UPLC BEH300 C18 column...

Protection of Ischemic Postconditioning against Neuronal Apoptosis Induced by Transient Focal Ischemia Is Associated with Attenuation of NF-κB/p65 Activation

Background and Purpose Accumulating evidences have demonstrated that nuclear factor κB/p65 plays a protective role in the protection of ischemic preconditioning and detrimental role in lethal ischemia-induced programmed cell death including apoptosis and autophagic death. However, its role in the protection of ischemic postconditioning is still unclear. Methods Rat MCAO model was...

The effects of lead time and visual aids in TTO valuation: a study of the EQ-VT framework

Background The effect of lead time in time trade-off (TTO) valuation is not well understood. The purpose of this study was to investigate the effects on health-state valuation of the length of lead time and the way the lead-time TTO task is displayed visually. Methods Using two general population samples, we compared three lead-time TTO variants: 10 years of lead time in full...

Iterative Nonlocal Total Variation Regularization Method for Image Restoration

In this paper, a Bregman iteration based total variation image restoration algorithm is proposed. Based on the Bregman iteration, the algorithm splits the original total variation problem into sub-problems that are easy to solve. Moreover, non-local regularization is introduced into the proposed algorithm, and a method to choose the non-local filter parameter locally and...

HPS4/SABRE regulates plant responses to phosphate starvation through antagonistic interaction with ethylene signalling

The phytohormone ethylene plays important roles in regulating plant responses to phosphate (Pi) starvation. To date, however, no molecular components have been identified that interact with ethylene signalling in regulating such responses. In this work, an Arabidopsis mutant, hps4, was characterized that exhibits enhanced responses to Pi starvation, including increased inhibition...