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Search: authors:"Nicholas A. Zumwalde"

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Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells

Antimicrobial T cells play key roles in the disease progression of cancers arising in mucosal epithelial tissues, such as the colon. However, little is known about microbe-reactive T cells within human breast ducts and whether these impact breast carcinogenesis. Epithelial ducts were isolated from primary human breast tissue samples, and the associated T lymphocytes were...