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Term sets: A transparent and reproducible representation of clinical code sets

and Social Care. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The time of Niels Peek was also Objective Materials and ... Peek. Software: Richard Williams. Writing ? original draft: Richard Williams. Writing ? review & editing: Benjamin Brown, Evan Kontopantelis, Tjeerd van Staa, Niels Peek. 1. SNOMED International

Three controversies in health data science

The routine operation of modern healthcare systems produces a wealth of data in electronic health records, administrative databases, clinical registries, and other clinical systems. It is widely acknowledged that there is great potential for utilising these routine data for health research to derive new knowledge about health, disease, and treatments. However, the reuse of...

The association between outcome-based quality indicators for intensive care units

Contributions Conceptualization: Ilona W. M. Verburg, Evert de Jonge, Nicolette F. de Keizer. Formal analysis: Ilona W. M. Verburg. Methodology: Ilona W. M. Verburg, Niels Peek. Supervision: Nicolette F. de ... Keizer. Writing ? original draft: Ilona W. M. Verburg. Writing ? review & editing: Evert de Jonge, Niels Peek, Nicolette F. de Keizer. 12 / 14 13 / 14 1. Kolfschoten NE , Kievit J , Gooiker GA , van

An exploration of mortality risk factors in non-severe pneumonia in children using clinical data from Kenya

Childhood pneumonia is the leading infectious cause of mortality in children younger than 5 years old. Recent updates to World Health Organization pneumonia guidelines recommend outpatient care for a population of children previously classified as high risk. This revision has been challenged by policymakers in Africa, where mortality related to pneumonia is higher than in other...

Clinical prediction in defined populations: a simulation study investigating when and how to aggregate existing models

Background Clinical prediction models (CPMs) are increasingly deployed to support healthcare decisions but they are derived inconsistently, in part due to limited data. An emerging alternative is to aggregate existing CPMs developed for similar settings and outcomes. This simulation study aimed to investigate the impact of between-population-heterogeneity and sample size on...

Health professionals’ perceptions about their clinical performance and the influence of audit and feedback on their intentions to improve practice: a theory-based study in Dutch intensive care units

Audit and feedback aims to guide health professionals in improving aspects of their practice that need it most. Evidence suggests that feedback fails to increase accuracy of professional perceptions about clinical performance, which likely reduces audit and feedback effectiveness. This study investigates health professionals’ perceptions about their clinical performance and the...

Effect of a web-based audit and feedback intervention with outreach visits on the clinical performance of multidisciplinary teams: a cluster-randomized trial in cardiac rehabilitation

Background The objective of this study was to assess the effect of a web-based audit and feedback (A&F) intervention with outreach visits to support decision-making by multidisciplinary teams. Methods We performed a multicentre cluster-randomized trial within the field of comprehensive cardiac rehabilitation (CR) in the Netherlands. Our participants were multidisciplinary teams...

An external validation of models to predict the onset of chronic kidney disease using population-based electronic health records from Salford, UK

Background Chronic kidney disease (CKD) is a major and increasing constituent of disease burdens worldwide. Early identification of patients at increased risk of developing CKD can guide interventions to slow disease progression, initiate timely referral to appropriate kidney care services, and support targeting of care resources. Risk prediction models can extend laboratory...

Comparison of Regression Methods for Modeling Intensive Care Length of Stay

Niels Peek 0 Jorge I.F. Salluh, D'or Institute of Research and Education, Brazil 0 1 Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands, 2

A multifaceted feedback strategy alone does not improve the adherence to organizational guideline-based standards: a cluster randomized trial in intensive care

Background Organizational data such as bed occupancy rate and nurse-to-patient ratio are related to clinical outcomes and to the efficient use of intensive care unit (ICU) resources. Standards for these performance indicators are provided in guidelines. We studied the effects of a multifaceted feedback strategy to improve the adherence to these standards. Methods In a cluster...

Effects and costs of home-based training with telemonitoring guidance in low to moderate risk patients entering cardiac rehabilitation: The FIT@Home study

Background Physical training has beneficial effects on exercise capacity, quality of life and mortality in patients after a cardiac event or intervention and is therefore a core component of cardiac rehabilitation. However, cardiac rehabilitation uptake is low and effects tend to decrease after the initial rehabilitation period. Home-based training has the potential to increase...

Evaluating the effect of a web-based quality improvement system with feedback and outreach visits on guideline concordance in the field of cardiac rehabilitation: rationale and study protocol

Background Implementation of clinical practice guidelines into daily care is hampered by a variety of barriers related to professional knowledge and collaboration in teams and organizations. To improve guideline concordance by changing the clinical decision-making behavior of professionals, computerized decision support (CDS) has been shown to be one of the most effective...

Setting Priorities for Optimizing Vascular Access Decision Making – An International Survey of Patients and Clinicians

Background Many decisions around vascular access for haemodialysis warrant a collaborative treatment decision-making process, involving both clinician and patient. Yet, patients’ experiences in this regard have been suboptimal. Although clinical practice guidelines could facilitate collaborative decision making, they often focus on the clinicians’ side of the process, while...

An online survey to study the relationship between patients’ health literacy and coping style and their preferences for self-management-related information

An online survey to study the relationship between patients’ health literacy and coping style and their preferences for self-management-related information Sandra Vosbergen,1 Niels Peek,1 Johanna MR

Effectiveness of a web-based health risk assessment with individually-tailored feedback on lifestyle behaviour: study protocol

Background Physical inactivity, unhealthy dietary habits, smoking and high alcohol consumption are recognized risk factors for cardiovascular disease and cancer. Web-based health risk assessments with tailored feedback seem promising in promoting a healthy lifestyle. This study evaluates the effectiveness of a web-based health risk assessment with individually-tailored feedback...

Do Intensive Care Data on Respiratory Infections Reflect Influenza Epidemics?

Objectives Severe influenza can lead to Intensive Care Unit (ICU) admission. We explored whether ICU data reflect influenza like illness (ILI) activity in the general population, and whether ICU respiratory infections can predict influenza epidemics. Methods We calculated the time lag and correlation between ILI incidence (from ILI sentinel surveillance, based on general...

Evaluating the effectiveness of a tailored multifaceted performance feedback intervention to improve the quality of care: protocol for a cluster randomized trial in intensive care

Background Feedback is potentially effective in improving the quality of care. However, merely sending reports is no guarantee that performance data are used as input for systematic quality improvement (QI). Therefore, we developed a multifaceted intervention tailored to prospectively analyzed barriers to using indicators: the Information Feedback on Quality Indicators (InFoQI...

The influence of volume and intensive care unit organization on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study

Introduction The aim of the study was to assess the influence of annual volume and factors related to intensive care unit (ICU) organization on in-hospital mortality among patients admitted to the ICU with severe sepsis. Methods A retrospective cohort study was conducted using the database of the Dutch National Intensive Care Evaluation (NICE) registry. Analyses were based on...