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Maternal body mass index and risk of neonatal adverse outcomes in China: a systematic review and meta-analysis

Maternal body mass index is linked to short- and long-term unfavorable health outcomes both for child and mother. We conducted a systematic review and meta-analysis of population-based cohort studies to evaluate maternal BMI and the risk of harmful neonatal outcomes in China. Six databases identified 2454 articles; 46 met the inclusion criteria for this study. The dichotomous...

Long noncoding RNA DANCR, working as a competitive endogenous RNA, promotes ROCK1-mediated proliferation and metastasis via decoying of miR-335-5p and miR-1972 in osteosarcoma

Accumulating evidences indicate that non-coding RNAs (ncRNAs) including long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) acting as crucial regulators in osteosarcoma (OS). Previously, we reported that Rho associated coiled-coil containing protein kinase 1 (ROCK1), a metastatic-related gene was negatively regulated by microRNA-335-5p (miR-335-5p) and work as an oncogene in...

Prognostic value of circulating plasma cells in patients with multiple myeloma: A meta-analysis

statistical method, and Dr Robert P. Seifert for critiquing the manuscript. Author Contributions Conceptualization: Ningning Wang. Data curation: Jia Li, Ningning Wang. Formal analysis: Jia Li ... . Investigation: Ningning Wang. Project administration: Baohong Yue. Software: Jia Li. Supervision: Shuai Liu, Baohong Yue. Validation: Shuai Liu, Baohong Yue. Writing ± original draft: Jia Li. Methodology: Jia

Channel Coordination in Logistics Service Supply Chain considering Fairness

January 2016; Accepted 6 March 2016 Academic Editor: Sri Sridharan Copyright © 2016 Ningning Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which

Channel Coordination in Logistics Service Supply Chain considering Fairness

January 2016; Accepted 6 March 2016 Academic Editor: Sri Sridharan Copyright © 2016 Ningning Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which

Fine mapping of a male sterility gene ms-3 in a novel cucumber (Cucumis sativus L.) mutant

Key message The cucumber male sterility gene ms - 3 was fine mapped in a 76 kb region harboring an MMD1 -like gene Csa3M006660 that may be responsible for the male sterile in cucumber. Abstract A cucumber (Cucumis sativus L.) male sterile mutant (ms-3) in an advanced-generation inbred line was identified, and genetic analysis revealed that the male sterility trait was controlled...

Existence of Nonradial Solutions for Hénon Type Biharmonic Equation Involving Critical Sobolev Exponents

We prove the existence of nonradial solutions under some conditions for a semilinear biharmonic Dirichlet problem involving critical Sobolev exponents.

Existence of Positive Solutions of Semilinear Biharmonic Equations

This paper is concerned with the existence of positive solutions of semilinear biharmonic problem whose associated functionals do not satisfy the Palais-Smale condition.

The roles of oxidative stress, endoplasmic reticulum stress, and autophagy in aldosterone/mineralocorticoid receptor-induced podocyte injury

Podocytes play an important role in the pathogenesis and progression of glomerulosclerosis. Recent studies indicate that aldosterone/mineralocorticoid receptor (MR) is a major contributor of chronic kidney disease (CKD) progression. Aldosterone/MR induces glomerular podocyte injury, causing the disruption of the glomerular filtration barrier and proteinuria. The present study...

E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment

Background Refractory surface of wound and dermal chronic ulcer are largely attributed to poor neovascularization. We have previously shown that E2F1 suppresses VEGF expression in the ischemic heart, and that genetic deletion of E2F1 leads to better cardiac recovery. However, whether E2F1 has a role in dermal wound healing is currently not known. Methods and Results Skin wounds...

Diagnostic Accuracy Study of Intraoperative and Perioperative Serum Intact PTH Level for Successful Parathyroidectomy in 501 Secondary Hyperparathyroidism Patients

• PubMed • Google ScholarSearch for Ningning Wang in:Nature Research journals • PubMed • Google Scholar Contributions N.W. and X.Z. conceived research; N.W. and X.Z. designed the study; C.X. managed the ... Correspondence to Xiaoming Zha or Ningning Wang. Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this

Similar Metabolic Changes Induced by HIPVs Exposure as Herbivore in Ammopiptanthus mongolicus

Herbivore-induced plant volatiles (HIPVs) are important compounds to prim neighboring undamaged plants; however, the mechanism for this priming process remains unclear. To reveal metabolic changes in plants exposed to HIPVs, metabolism of leaves and roots of Ammopiptanthus mongolicus seedlings exposed to HIPVs released from conspecific plants infested with larvae of Orgyia ericae...

Tissue Culture-Induced Heritable Genomic Variation in Rice, and Their Phenotypic Implications

Background Somaclonal variation generally occurs in plants regenerated from tissue culture. However, fundamental issues regarding molecular characteristics, mutation rates and mutation spectra of plant somatic variation as well as their phenotypic relevance have been addressed only recently. Moreover, these studies have reported highly discrepant results in different plant...

Mutation of the RDR1 gene caused genome-wide changes in gene expression, regional variation in small RNA clusters and localized alteration in DNA methylation in rice

Background Endogenous small (sm) RNAs (primarily si- and miRNAs) are important trans/cis-acting regulators involved in diverse cellular functions. In plants, the RNA-dependent RNA polymerases (RDRs) are essential for smRNA biogenesis. It has been established that RDR2 is involved in the 24 nt siRNA-dependent RNA-directed DNA methylation (RdDM) pathway. Recent studies have...

Transpositional reactivation of the Dart transposon family in rice lines derived from introgressive hybridization with Zizania latifolia

Background It is widely recognized that interspecific hybridization may induce "genome shock", and lead to genetic and epigenetic instabilities in the resultant hybrids and/or backcrossed introgressants. A prominent component involved in the genome shock is reactivation of cryptic transposable elements (TEs) in the hybrid genome, which is often associated with alteration in the...