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8 papers found.
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Development of high-performance two-dimensional gel electrophoresis for human hair shaft proteome

, potentially including biomarkers studies related to hair health, diseases and ageing. Author Contributions Conceptualization: Sing Ying Wong, Onn Haji Hashim, Nobuhiro Hayashi. Data curation: Sing Ying Wong ... , Onn Haji Hashim, Nobuhiro Hayashi. Funding acquisition: Nobuhiro Hayashi. Investigation: Sing Ying Wong, Nobuhiro Hayashi. Methodology: Sing Ying Wong, Onn Haji Hashim, Nobuhiro Hayashi. Project

Low-dose ionizing radiation exposure represses the cell cycle and protein synthesis pathways in in vitro human primary keratinocytes and U937 cell lines

, Juntendo University Graduate School of Medicine and Department of Radiation Oncology, Juntendo University Hospital, for use of facilities. Author Contributions Conceptualization: Nobuhiro Hayashi, Keisuke

Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure

Background The myelin sheath is a multilamellar membrane structure wrapped around the axon, enabling the saltatory conduction of nerve impulses in vertebrates. Myelin basic protein, one of the most abundant myelin-specific proteins, is an intrinsically disordered protein that has been shown to bind calmodulin. In this study, we focus on a 19-mer synthetic peptide from the...

A liquid chromatography/electrospray mass spectrometric study on the post-transcriptional modification of tRNA

Liquid chromatography/electrospray mass spectrometry is one of the rapidly developing techniques with which mass of large hydrophilic polymers such as proteins and nucleic acids can be determined precisely. The technique was applied to studies on the modifications of tRNAs. Various tRNA species purified from Escherichia coli were directly injected into a capillary reversed-phase...

MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins

Sebastian Maurer-Stroh*, Masaki Gouda, Maria Novatchkova*, Alexander Schleiffer*, Georg Schneider*, Fernanda L Sirota, Michael Wildpaner*, Nobuhiro Hayashi and Frank Eisenhaber* Correspondence: Sebastian