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Search: authors:"Ondrej Hradsky"

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The CTLA4 variants may interact with the IL23R- and NOD2-conferred risk in development of Crohn's disease

Background The CTLA4 (cytotoxic T-lymphocyte antigen 4) gene is associated with several immunopathologic diseases and because of its important immuno-regulatory role it may be considered also a plausible candidate for a genetic association with inflammatory bowel diseases. Previously published studies found no association of CTLA4 with Crohn's disease itself, but some indicated...