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Search: authors:"Osamu Ohneda"

6 papers found.
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Deterioration of alveolar development in mice with both HIF-3α knockout and HIF-2α knockdown

ObjectiveEarlier studies from our group using hypoxia-inducible factor 3α knockout mice showed impairments in lung remodeling and lung endothelial cells. Another research from our group demonstrated that impaired expression of hypoxia-inducible factor 2α induced compensatory expression of hypoxia-inducible factor 1α in hypoxia-inducible factor 2α knockdown mice. The present study...

Comparative Analysis of Cellular and Growth Factor Composition in Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma

Kumagai,3 Kojiro Hyodo,3 Osamu Ohneda,2 Masashi Yamazaki,3 and Hajime Mishima3 1Division of Regenerative Medicine for Musculoskeletal System, Department of Orthopedics Surgery, Faculty of Medicine

Comparative Analysis of Cellular and Growth Factor Composition in Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma

Kumagai,3 Kojiro Hyodo,3 Osamu Ohneda,2 Masashi Yamazaki,3 and Hajime Mishima3 1Division of Regenerative Medicine for Musculoskeletal System, Department of Orthopedics Surgery, Faculty of Medicine

Molecular Therapeutic Targets for Glioma Angiogenesis

Due to the prominent angiogenesis that occurs in malignant glioma, antiangiogenic therapy has been attempted. There have been several molecular targets that are specific to malignant gliomas, as well as more broadly in systemic cancers. In this review, I will focus on some topics related to molecular therapeutic targets for glioma angiogenesis. First, important angiogenic factors...

Molecular Therapeutic Targets for Glioma Angiogenesis

Due to the prominent angiogenesis that occurs in malignant glioma, antiangiogenic therapy has been attempted. There have been several molecular targets that are specific to malignant gliomas, as well as more broadly in systemic cancers. In this review, I will focus on some topics related to molecular therapeutic targets for glioma angiogenesis. First, important angiogenic factors...

Direct Binding of pRb/E2F-2 to GATA-1 Regulates Maturation and Terminal Cell Division during Erythropoiesis

Cell differentiation is often coupled with cell cycle arrest. Here, we show that direct binding of the erythroid transcription factor GATA-1 to the retinoblastoma protein and the pRb/E2F transcription factor complex is critical for red blood cell formation.