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A nested case-control study of 277 prediagnostic serum cytokines and glioma

Recent research shows bidirectional communication between the normal brain and the peripheral immune system. Glioma is a primary brain tumor characterized by systemic immunosuppression. To better understand gliomagenesis, we evaluated associations between 277 prediagnostic serum cytokines and glioma. We used glioma (n = 487) and matched control (n = 487) specimens from the Janus...

Lineage-specific late pleistocene expansion of an endemic subtropical gossamer-wing damselfly, Euphaea formosa, in Taiwan

Background Pleistocene glacial oscillations have significantly affected the historical population dynamics of temperate taxa. However, the general effects of recent climatic changes on the evolutionary history and genetic structure of extant subtropical species remain poorly understood. In the present study, phylogeographic and historical demographic analyses based on...

Fuzzy Morphological Polynomial Image Representation

A novel signal representation using fuzzy mathematical morphology is developed. We take advantage of the optimum fuzzy fitting and the efficient implementation of morphological operators to extract geometric information from signals. The new representation provides results analogous to those given by the polynomial transform. Geometrical decomposition of a signal is achieved by...

Association between Prediagnostic Allergy-Related Serum Cytokines and Glioma

-Pan Huang, Brett Burkholder; Buckeye Psychiatry: Adam Brandemihl), but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the ... manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section. Competing Interests: Ruo-Pan Huang and Brett Burkholder are employed by RayBiotech, Inc. and Adam

N-n-butyl haloperidol iodide inhibits H2O2- induced Na+/Ca2+-exchanger activation via the Na+/H+ exchanger in rat ventricular myocytes

N-n-butyl haloperidol iodide inhibits H2O2- induced Na+/Ca2+-exchanger activation via the Na+/H+ exchanger in rat ventricular myocytes Yong-Pan Huang,1,* Fen-Fei Gao,1,* Bin Wang,1 Fu-Chun Zheng,2 ... ; Na+/Ca2+ exchanger; Na+/H+ - deda ropF open access to scientific and medical research O r i g i n a l r e s e a r c h Yong-Pan huang 1,* Fen-Fei gao 1,* Bin Wang1 Fu-chun Zheng 2 Yi-cun chen 1

Identification of Five Serum Protein Markers for Detection of Ovarian Cancer by Antibody Arrays

BackgroundProtein and antibody arrays have emerged as a promising technology to study protein expression and protein function in a high-throughput manner. These arrays also represent a new opportunity to profile protein expression levels in cancer patients’ samples and to identify useful biosignatures for clinical diagnosis, disease classification, prediction, drug development...

Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain

Vardarajan 8 Ruo-Pan Huang 6 7 Elizabeth D. Kirby 0 Rachelle Abbey 0 Bradley F. Boeve 5 Adam L. Boxer 10 Lindsay A. Farrer 8 9 NiCole Finch 4 Neill R. Graff-Radford Elizabeth Head Matan Hofree Ruochun Huang 6

Development of IGF Signaling Antibody Arrays for the Identification of Hepatocellular Carcinoma Biomarkers

Zhong-Sheng Wang 0 Ruo-Pan Huang 0 Bin He, Baylor College of Medicine, United States of America 0 1 Department of Hepatobiliary Surgery, the First Affiliated Hospital, Sun Yat-Sen University , Guangzhou ... , decision to publish, or preparation of the manuscript. Competing Interests: Ying-Qing Mao, Wei-Dong Jiang, Yun-Ru Chen, Zhi Shi, Yan-Li Liu and Ruo-Pan Huang are the employees of RayBiotech, Inc. This does