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31 papers found.
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Functional IGF1R variant predicts breast cancer risk in women with preeclampsia in California Teachers Study

Purpose Hypertension in pregnancy has been associated with decreased future risk of breast cancer in many but not all studies. In the Marin Women’s Study, pregnancy-induced hypertension was shown to interact with the T allele of a functional IGF1R gene variant, rs2016347, to result in lower breast density, as well as decreased breast cancer risk. Our objective was to explore...

Lifetime body size and estrogen-receptor-positive breast cancer risk in the California Teachers Study cohort

Leslie Bernstein Susan L. Neuhausen David O. Nelson Peggy Reynolds 0 Cancer Prevention Institute of California , 2201 Walnut Ave, Suite 300, Fremont, CA 94538 , USA Background: Obesity is a public health

Hazardous air pollutants and breast cancer risk in California teachers: a cohort study

Background Studies suggest that higher breast cancer rates in urban areas persist after accounting for the prevalence of known risk factors, leading to speculation that urban environmental exposures, such as air pollution, may play a role in the etiology of breast cancer. Combining modeled ambient air concentrations with data from a large prospective cohort of California women...

Representativeness of breast cancer cases in an integrated health care delivery system

Background Integrated health care delivery systems, with their comprehensive and integrated electronic medical records (EMR), are well-poised to conduct research that leverages the detailed clinical data within the EMRs. However, information regarding the representativeness of these clinical populations is limited, and thus the generalizability of research findings is uncertain...

Associations between self-reported pest treatments and pesticide concentrations in carpet dust

Peggy Reynolds Benjamin Booth 0 Catherine Metayer Mary H Ward 0 0 Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National

A cross-sectional analysis of light at night, neighborhood sociodemographics and urinary 6-sulfatoxymelatonin concentrations: implications for the conduct of health studies

Background There is accumulating evidence that circadian disruption, mediated by alterations in melatonin levels, may play an etiologic role in a wide variety of diseases. The degree to which light-at-night (LAN) and other factors can alter melatonin levels is not well-documented. Our primary objective was to evaluate the degree to which estimates of outdoor environmental LAN...

Novel polymorphisms in caspase-8 are associated with breast cancer risk in the California Teachers Study

Background The ability of tamoxifen and raloxifene to decrease breast cancer risk varies among different breast cancer subtypes. It is important to determine one’s subtype-specific breast cancer risk when considering chemoprevention. A number of single nucleotide polymorphisms (SNPs), including one in caspase-8 (CASP8), have been previously associated with risk of developing...

Menopausal Hormone Therapy and Lung Cancer-Specific Mortality Following Diagnosis: The California Teachers Study

Previous results from research on menopausal hormone therapy (MHT) and lung cancer survival have been mixed and most have not studied women who used estrogen therapy (ET) exclusively. We examined the associations between MHT use reported at baseline and lung cancer-specific mortality in the prospective California Teachers Study cohort. Among 727 postmenopausal women diagnosed...

Cigarette Smoking, Passive Smoking, and Non-Hodgkin Lymphoma Risk: Evidence From the California Teachers Study

); and Cancer Prevention Institute of California, Fremont, California (Peggy Reynolds, Ellen T. Chang, Christina A. Clarke). This work was supported by the California Breast Cancer Act of 1993; the

Birth Characteristics and Risk of Neuroblastoma in Young Children

The peak incidence of neuroblastoma during infancy suggests that certain prenatal or perinatal factors may be etiologically important. In this population-based study, California birth certificates were identified for 508 (86%) neuroblastoma cases diagnosed at less than 5 years of age between 1988 and 1997. For each case, two controls, matched on date of birth and gender, were...

Current practices in spatial analysis of cancer data: data characteristics and data sources for geographic studies of cancer

Ward 1 Peggy Reynolds 0 0 California Department of Health Services, Environmental Health Investigations Branch , Oakland, CA , USA 1 Occupational and Environmental Epidemiology Branch, Division of

Cancer Incidence in Female Cosmetologists and Manicurists in California, 1988–2005

Ngoc Tran Julie Von Behren Peggy Reynolds Health concerns have been pronounced for cosmetologists and manicurists, who are exposed daily to cosmetic products containing known or suspected human ... . ACKNOWLEDGMENTS Author affiliations: Cancer Prevention Institute of California, Berkeley, California (Thu Quach, Michael Layefsky, David Nelson, Julie Von Behren, Peggy Reynolds); Asian Health Services, Oakland

RESPONSE: Re: Active Smoking, Household Passive Smoking, and Breast Cancer: Evidence From the California Teachers Study

(1.02 to 1.61) .022 life, which may be especially important. We also look forward to comparing these results with those from the Canadian study (2). PEGGY REYNOLDS SUSAN HURLEY DEBBIE GOLDBERG CTS

Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study cohort

Background We investigated the association between hypertension, antihypertensive (AH) medication use, and breast cancer in a large prospective study, the California Teachers Study (CTS). Methods Information on history of hypertension and lifetime regular use of AH medications was collected from 114,549 women in 1995–1996. Among them, 4,151 invasive breast cancers were diagnosed...

Birth Characteristics and Leukemia in Young Children

The relation between birth characteristics and leukemia in young children was investigated in a large population-based study in California. Cases were obtained from the statewide cancer registry for 1988–1997. During this time, 1,957 leukemia cases were diagnosed among children under age 5 years. Of these, 1,728 (88%) were matched to a California birth certificate. Two control...

Is House-Dust Nicotine a Good Surrogate for Household Smoking?

California Cancer Center, Berkeley, California (Robert Gunier, Peggy Reynolds). This work was supported by the National Institute of Environmental Health Sciences (grants R01ES009137, P-42-ES-04705-18), the

Control Selection Strategies in Case-Control Studies of Childhood Diseases

Reynolds 3 4 0 Public Health Institute , Oakland, CA 1 Division of Public Health Biology and Epidemiology, University of California , Berkeley, CA 2 Department of Epidemiology and Public Health, Yale

Household vacuum cleaners vs. the high-volume surface sampler for collection of carpet dust samples in epidemiologic studies of children

Background Levels of pesticides and other compounds in carpet dust can be useful indicators of exposure in epidemiologic studies, particularly for young children who are in frequent contact with carpets. The high-volume surface sampler (HVS3) is often used to collect dust samples in the room in which the child had spent the most time. This method can be expensive and cumbersome...

Household vacuum cleaners vs. the high-volume surface sampler for collection of carpet dust samples in epidemiologic studies of children

Levels of pesticides and other compounds in carpet dust can be useful indicators of exposure in epidemiologic studies, particularly for young children who are in frequent contact with carpets. The high-volume surface sampler (HVS3) is often used to collect dust samples in the room in which the child had spent the most time. This method can be expensive and cumbersome, and it has...