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CT utilization abruptly increases at age 18 among patients with inflammatory bowel diseases in the hospital

) 7 / 9 Author Contributions Conceptualization: Shail M. Govani, Peter D. R. Higgins, Joel H. Rubenstein, Akbar K. Waljee. Data curation: Shail M. Govani. Formal analysis: Shail M. Govani ... & editing: Shail M. Govani, Peter D. R. Higgins, Joel H. Rubenstein, Ryan W. Stidham, Akbar K. Waljee. 8 / 9 14. 1. Loftus EV. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence

Serum Glycoproteome Profiles for Distinguishing Intestinal Fibrosis from Inflammation in Crohn's Disease

Background Reliable identification and quantitation of intestinal fibrosis in the setting of co-existing inflammation due to Crohn’s disease (CD) is difficult. We aimed to identify serum biomarkers which distinguish inflammatory from fibrostenotic phenotypes of CD using serum glycoproteome profiles. Methods Subjects with fibrostenotic and inflammation-predominant CD phenotypes (n...

Assessing risk of fibrosis progression and liver-related clinical outcomes among patients with both early stage and advanced chronic hepatitis C

Verma, Nizar Talaat, Ulysses Balis. Formal analysis: Monica A. Konerman, Yiwei Zhang, Boang Liu. Funding acquisition: Peter D. R. Higgins. Investigation: Monica A. Konerman. Methodology: Monica A ... . Konerman, Yiwei Zhang, Ji Zhu, Boang Liu, Akbar K. Waljee. Supervision: Ji Zhu, Peter D. R. Higgins, Anna S. F. Lok, Akbar K. Waljee. Validation: Yiwei Zhang, Ji Zhu, Boang Liu. Writing ± original draft

Corticosteroid Use and Complications in a US Inflammatory Bowel Disease Cohort

Background and Aims Corticosteroids are effective for the short-term treatment of inflammatory bowel disease (IBD). Long-term use, however, is associated with significant adverse effects. To define the: (1) frequency and duration of corticosteroid use, (2) frequency of escalation to corticosteroid-sparing therapy, (3) rate of complications related to corticosteroid use, (4) rate...

A Primer on Predictive Models

Prediction research is becoming increasing popular; however, the differences between traditional explanatory research and prediction research are often poorly understood, resulting in a wide variation in the methodologic quality of prediction research. This primer describes the basic methods for conducting prediction research in gastroenterology and highlights differences between...