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33 papers found.
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When drug treatments bias genetic studies: Mediation and interaction

curation. Author Contributions Conceptualization: Amand F. Schmidt, Hiddo J. L. Heerspink, Chris Finan, Rolf H. H. Groenwold. Data curation: Amand F. Schmidt, Petra Denig, Chris Finan. Formal analysis ... : Amand F. Schmidt. Investigation: Hiddo J. L. Heerspink, Petra Denig. Methodology: Amand F. Schmidt, Rolf H. H. Groenwold. Supervision: Hiddo J. L. Heerspink, Petra Denig, Chris Finan, Rolf H. H

Trends in polypharmacy and dispensed drugs among adults in the Netherlands as compared to the United States

Conceptualization: Monika P. Oktora, Petra Denig, Eelko Hak. Data curation: Monika P. Oktora, Jens H. J. Bos, Eelko Hak. Formal analysis: Monika P. Oktora, Petra Denig, Catharina C. M. Schuiling-Veninga, Eelko Hak ... . Funding acquisition: Monika P. Oktora, Petra Denig. Investigation: Monika P. Oktora, Petra Denig, Eelko Hak. Methodology: Monika P. Oktora, Petra Denig, Eelko Hak. Project administration: Monika P

Use of a Patient-Friendly Terms List in the Adverse Drug Reaction Report Form: A Database Study

/2007-2013 and the EFPIA companies’ in kind contribution (, UK). Conflict of Interest Sieta T. de Vries, Petra Denig and Peter G.M. Mol have no conflicts of interest that are directly

Is guideline-adherent prescribing associated with quality of life in patients with type 2 diabetes?

Bouma Marianne Meulepas 1 Gerjan Navis Henk J. G. Bilo Petra Denig 0 Antonio Palazo?n-Bru, Universidad Miguel Hernandez de Elche, SPAIN 0 Department of Clinical Pharmacy and Pharmacology, University ... , Grigory Sidorenkov, Margriet Bouma, Marianne Meulepas, Gerjan Navis, Henk J. G. Bilo, Petra Denig. Data curation: Kirsten P. J. Smits, Steven H. Hendriks, Henk J. G. Bilo. Formal analysis: Kirsten P. J

Role of Patient and Practice Characteristics in Variance of Treatment Quality in Type 2 Diabetes between General Practices

Background Accounting for justifiable variance is important for fair comparisons of treatment quality. The variance between general practices in treatment quality of type 2 diabetes (T2DM) patients may be attributed to the underlying patient population and practice characteristics. The objective of this study is to describe the between practice differences in treatment, and...

Interest in a Mobile App for Two-Way Risk Communication: A Survey Study Among European Healthcare Professionals and Patients

Union’s Seventh Framework Programme FP7/2007-2013 and EFPIA companies’ in kind contribution,, UK. Conflict of interest Sieta T. de Vries, Petra Denig, Carmen Lasheras Ruiz, Franc

Identification of major cardiovascular events in patients with diabetes using primary care data

Denig 0 Unit of PharmacoEpidemiology and PharmacoEconomics, Department of Pharmacy, University of Groningen , Antonius Deusinglaan 1, 9713 AV Groningen , The Netherlands Background: Routine primary care

Identification of major cardiovascular events in patients with diabetes using primary care data

Routine primary care data are increasingly being used for evaluation and research purposes but there are concerns about the completeness and accuracy of diagnoses and events captured in such databases. We evaluated how well patients with major cardiovascular disease (CVD) can be identified using primary care morbidity data and drug prescriptions. The study was conducted using...

Safety Communication Tools and Healthcare Professionals’ Awareness of Specific Drug Safety Issues in Europe: A Survey Study

´ Mart´ınez, Amelia Cupelli, Ilaria Baldelli, Ivana Sˇ ipic´, Adriana Andric´, Line Michan, and Petra Denig have no conflicts of interest that are directly relevant to the content of this study. Peter G.M

Efficacy of Standard and Intensive Statin Treatment for the Secondary Prevention of Cardiovascular and Cerebrovascular Events in Diabetes Patients: A Meta-Analysis

Aims To estimate the efficacy of standard and intensive statin treatment in the secondary prevention of major cardiovascular and cerebrovascular events in diabetes patients. Methods A systematic search was conducted in Medline over the years 1990 to September 2013. Randomized, double-blind, clinical trials comparing a standard-dose statin with placebo or a standard-dose statin...

Communication on Safety of Medicines in Europe: Current Practices and General Practitioners’ Awareness and Preferences

Montero, Ivana Sˇ ipic´, Adriana Andric´, Annika Wennberg, Jane Ahlqvist-Rastad and Petra Denig have no conflicts of interest to declare that are directly relevant to the content of this study. Maartje J

Construct and concurrent validity of a patient-reported adverse drug event questionnaire: a cross-sectional study

Dick de Zeeuw 0 Petra Denig 0 0 Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen , PO Box 197, 9700 AD Groningen , The Netherlands Background: Direct patient

Potential Overtreatment and Undertreatment of Diabetes in Different Patient Age Groups in Primary Care After the Introduction of Performance Measures

–1320 | DOI: 10.2337/dc13-1861 Sieta T. de Vries, Jaco Voorham, Flora M. Haaijer-Ruskamp, and Petra Denig The quality of diabetes care, and in particular potential undertreatment of cardiometabolic risk

The Role of Patients’ Age on Their Preferences for Choosing Additional Blood Pressure-Lowering Drugs: A Discrete Choice Experiment in Patients with Diabetes

Objectives To assess whether patients’ willingness to add a blood pressure-lowering drug and the importance they attach to specific treatment characteristics differ among age groups in patients with type 2 diabetes. Materials and Methods Patients being prescribed at least an oral glucose-lowering and a blood pressure-lowering drug completed a questionnaire including a discrete...

Do Treatment Quality Indicators Predict Cardiovascular Outcomes in Patients with Diabetes?

Background Landmark clinical trials have led to optimal treatment recommendations for patients with diabetes. Whether optimal treatment is actually delivered in practice is even more important than the efficacy of the drugs tested in trials. To this end, treatment quality indicators have been developed and tested against intermediate outcomes. No studies have tested whether these...

The effect of a patient-oriented treatment decision aid for risk factor management in patients with diabetes (PORTDA-diab): study protocol for a randomised controlled trial

Background To improve risk factor management in diabetes, we need to support effective interactions between patients and healthcare providers. Our aim is to develop and evaluate a treatment decision aid that offers personalised information on treatment options and outcomes, and is intended to empower patients in taking a proactive role in their disease management. Important...

Is albuminuria screening and treatment optimal in patients with type 2 diabetes in primary care? Observational data of the GIANTT cohort

Background Failure of diagnosing and treatment of albuminuria play a role in morbidity and mortality in type 2 diabetes (T2DM). We evaluated guideline adherence and factors associated with albuminuria screening and treatment in T2DM patients in primary care.

A pilot qualitative study to explore stakeholder opinions regarding prescribing quality indicators

BackgroundInformation on prescribing quality of diabetes care is required by health care providers, insurance companies, policy makers, and the public. Knowledge regarding the opinions and preferences of all involved parties regarding prescribing quality information is important for effective use of prescribing quality indicators.MethodsBetween June and December 2009 we conducted...

Development and Initial Validation of a Patient-Reported Adverse Drug Event Questionnaire

Background Direct patient reporting of adverse drug events (ADEs) is relevant for the evaluation of drug safety. To collect such data in clinical trials and postmarketing studies, a valid questionnaire is needed that can measure all possible ADEs experienced by patients. Objective Our aim was to develop and test a generic questionnaire to identify ADEs and quantify their nature...