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Critically ill elderly patients (≥ 90 years): Clinical characteristics, outcome and financial implications

. Brunhuber for her English proofreading of the manuscript. Author Contributions Conceptualization: Pierrick Le Borgne, Sophie Couraud, Georges Kaltenbach, Pascal Bilbault, Francis Schneider. Data curation ... : Quentin Maestraggi, Sophie Couraud, Franc?ois Lefebvre. Formal analysis: Pierrick Le Borgne, Sophie Couraud, Franc?ois Lefebvre, Baptiste Michard, Francis Schneider. Investigation: Pierrick Le Borgne

Docosahexaenoic acid, but not eicosapentaenoic acid, improves septic shock-induced arterial dysfunction in rats

. Formal analysis: RaphaeÈl Clere-Jehl, Hamid Merdji, Ferhat Meziani. Funding acquisition: Julie Helms. Investigation: Alexandra Boivin, MeÂlanie Burban, RaphaeÈl Clere-Jehl, Pierrick Le Borgne

Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats

BackgroundSeptic shock-induced disseminated intravascular coagulation is responsible for increased occurrence of multiple organ dysfunction and mortality. Immunothrombosis-induced coagulopathy may contribute to hypercoagulability. We aimed at determining whether recombinant human thrombomodulin (rhTM) could control exaggerated immunothrombosis by studying procoagulant responses...