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The data and characteristics of the human milk banks in mainland China

Human Milk Bank Group, Children Health of the Chinese Medical Doctors Association: Xi-Hong Liu, Shu-Ping Han, Qiu-Fen Wei, Feng-Ying Zheng, Ting Zhang, Hui-Min Chen. Members list of Group of Child Health

Gene expression meta-analysis in diffuse low-grade glioma and the corresponding histological subtypes

Scholar Search for Haibo Xu in:Nature Research journals • PubMed • Google Scholar Search for Ping Han in:Nature Research journals • PubMed • Google Scholar Contributions Conceived and designed the study ... discussion. Competing Interests The authors declare that they have no competing interests. Corresponding authors Correspondence to Haibo Xu or Ping Han. Electronic supplementary material Supplementary

CRLF1 promotes malignant phenotypes of papillary thyroid carcinoma by activating the MAPK/ERK and PI3K/AKT pathways

Papillary thyroid carcinoma (PTC) is the one of the most common types of endocrine cancer and has a heterogeneous prognosis. Tumors from patients with poor prognosis may differentially express specific genes. Therefore, an analysis of The Cancer Genome Atlas (TCGA) database was performed and revealed that cytokine receptor-like factor 1 (CRLF1) may be a potential novel target for...

Pretreatment BMI Is Associated with Aggressive Clinicopathological Features of Papillary Thyroid Carcinoma: A Multicenter Study

Objectives. The aim of the present study was to analyze the association between pretreatment body mass index (BMI) and the aggressiveness of papillary thyroid carcinoma (PTC) along with its clinical outcomes in a Chinese population with BMI classification for Asians. Methods. A retrospective, observational study was conducted on patients from two teaching hospitals in China. 1622...

Pretreatment BMI Is Associated with Aggressive Clinicopathological Features of Papillary Thyroid Carcinoma: A Multicenter Study

Objectives. The aim of the present study was to analyze the association between pretreatment body mass index (BMI) and the aggressiveness of papillary thyroid carcinoma (PTC) along with its clinical outcomes in a Chinese population with BMI classification for Asians. Methods. A retrospective, observational study was conducted on patients from two teaching hospitals in China. 1622...

Identification of early ammonium nitrate-responsive genes in rice roots

Ammonium has long been used as the predominant form of nitrogen source for paddy rice (Oryza sativa). Recently, increasing evidence suggests that nitrate also plays an important role for nitrogen acquisition in the rhizosphere of waterlogged paddy rice. Ammonium and nitrate have a synergistic effect on promoting rice growth. However, the molecular responses induced by...

Genes Related to Oxytocin and Arginine-Vasopressin Pathways: Associations with Autism Spectrum Disorders

Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental disorders characterized by impaired social interactions, communication deficits, and repetitive behavior. Although the mechanisms underlying its etiology and manifestations are poorly understood, several lines of evidence from rodent and human studies suggest involvement of the evolutionarily highly-conserved...

Percutaneous nephrolithotomy versus retrograde intrarenal surgery for the treatment of kidney stones up to 2 cm in patients with solitary kidney: a single centre experience

Yunjin Bai 0 Xiaoming Wang 0 Yubo Yang Ping Han Jia Wang 0 Equal contributors Department of Urology, Institute of Urology, West China Hospital, Sichuan University , Chengdu , China Background: To compare

Parity and bladder cancer risk: a dose-response meta-analysis

Background Multiple studies have reported evidence of an inverse association between parity and bladder cancer risk. However, a comprehensive and quantitative assessment of this association has never been conducted. We conducted this study to clarify this issue. Methods Systematic search of PubMed and Embase was performed to identify all the studies. Studies were selected based...

The status of Her2 amplification and Kras mutations in mucinous ovarian carcinoma

Jayson GC et al. remarked in Lancet that nearly 100% of mucinous ovarian cancer cases have Kras mutation as well as a high frequency of Her2 amplification. Using the Abbott PathVysion Her2 DNA Probe Kit and Kras mutant-enriched PCR Kits (FemtoPath®), 21 samples of primary ovarian mucinous cystadenocarcinomas from Taiwanese patients were examined to determine the status of Her2...

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

It has been known that circular RNAs are widely expressed in human tissues and cells, and play important regulatory roles in physiological or pathological processes. However, there is lack of comprehensively annotated human circular RNAs database. In this study we established a circRNA database, named as circRNADb, containing 32,914 human exonic circRNAs carefully selected from...

Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis

The incidence of melanoma, the most aggressive and life-threatening form of skin cancer, has significantly risen over recent decades. Therefore, it is essential to identify the mechanisms that underlie melanoma tumorigenesis and metastasis and to explore novel and effective melanoma treatment strategies. Accumulating evidence s uggests that aberrantly expressed long noncoding...

Prognostic value of the C-reactive protein/albumin ratio in patients with laryngeal squamous cell carcinoma

Prognostic value of the C-reactive protein/albumin ratio in patients with laryngeal squamous cell carcinoma Shi-tong Yu,1,2,* Zhiwei Zhou,1,2,* Qian Cai,1,2 Faya Liang,1,2 Ping Han,1,2 Renhui Chen

The Effect of Tianmai Xiaoke Pian on Insulin Resistance through PI3-K/AKT Signal Pathway

In the clinical setting, given the potential adverse effects of thiazolidinediones and biguanides, we often have difficulty in treatment that no other insulin sensitizers are available for use in type 2 diabetic mellitus (T2DM) patients. Tianmai Xiaoke Pian (TMXKP) is a traditional Chinese medicine tablet, which is comprised of chromium picolinate, Tianhuafen, Maidong, and...

The Effect of Tianmai Xiaoke Pian on Insulin Resistance through PI3-K/AKT Signal Pathway

In the clinical setting, given the potential adverse effects of thiazolidinediones and biguanides, we often have difficulty in treatment that no other insulin sensitizers are available for use in type 2 diabetic mellitus (T2DM) patients. Tianmai Xiaoke Pian (TMXKP) is a traditional Chinese medicine tablet, which is comprised of chromium picolinate, Tianhuafen, Maidong, and...

Quantification of left coronary bifurcation angles and plaques by coronary computed tomography angiography for prediction of significant coronary stenosis: A preliminary study with dual-source CT

Purpose To evaluate the diagnostic performance of left coronary bifurcation angles and plaque characteristics for prediction of coronary stenosis by dual-source CT. Methods 106 patients suspected of coronary artery disease undergoing both coronary computed tomography angiography (CCTA) and invasive coronary angiography (CAG) within three months were included. Left coronary...

Acute blood glucose fluctuation enhances rat aorta endothelial cell apoptosis, oxidative stress and pro-inflammatory cytokine expression in vivo

Background Complications of diabetes mellitus (DM) are related not only to elevated plasma glucose, but also plasma glucose fluctuations. However, the specific mechanism underlying the role of plasma glucose fluctuation in the pathogenesis of DM complications remains poorly understood. In the present study, the influence of acute fluctuant hyperglycemia and persistent...

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Budnar, Shafali Gupta, Suzie Verma, Siew-Ping Han, Robert G. Parton, Nicholas A. Hamilton, Guillermo A. Gomez & Alpha S. YapThe University of Queensland Diamantina Institute, Brisbane, QLD, 4102 ... • Google Scholar Search for Shafali Gupta in:Nature Research journals • PubMed • Google Scholar Search for Suzie Verma in:Nature Research journals • PubMed • Google Scholar Search for Siew-Ping Han