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Immunological pathogenesis and treatment of systemic lupus erythematosus

and Mei-Ping Lu contributed equally to this work and should be considered co-first authors. Introduction Systemic lupus erythematosis (SLE) is a chronic autoimmune disease characterized by the

Low-Cycle Fatigue Properties of the X70 High-Frequency Electric-Resistant Welded Pipes

The strength, toughness, corrosion, and fatigue resistance are the main requirements for evaluating the integrity of a pipeline. In this study, the tensile strength, impact toughness, and fatigue properties of the pipe body and weld joint of an X70 high-frequency electric-resistant welded (HFW) pipe were measured and the effects of microstructure and surface defects at weld joint...

Low-Cycle Fatigue Properties of the X70 High-Frequency Electric-Resistant Welded Pipes

The strength, toughness, corrosion, and fatigue resistance are the main requirements for evaluating the integrity of a pipeline. In this study, the tensile strength, impact toughness, and fatigue properties of the pipe body and weld joint of an X70 high-frequency electric-resistant welded (HFW) pipe were measured and the effects of microstructure and surface defects at weld joint...

The Complexity of SORE-definability Problems

PhD. thesis of Ping Lu (cf. [25]). a a1 a a3 b a b a 1. For any a ? ?E, let ?E0(qI , a) = {a | ?i. ai ? ?E(qI , a)}; 2. For any a, b ? ?E, let ?E0(a, b) = {b | ?i, j. bj ? ?E(ai, b)}; 3. F E0 = {{aa ... Computation, 140(2):229?253, 1998. Haiming Chen and Ping Lu. Assisting the design of XML Schema: diagnosing nondeterministic content models. In Web Technologies and Applications, pages 301?312. Springer, 2011

HAMdb: a database of human autophagy modulators with specific pathway and disease information

Autophagy is an important homeostatic cellular recycling mechanism responsible for degrading unnecessary or dysfunctional cellular organelles and proteins in all living cells. In addition to its vital homeostatic role, this degradation pathway also involves in various human disorders, including metabolic conditions, neurodegenerative diseases, cancers and infectious diseases...

CD90 determined two subpopulations of glioma-associated mesenchymal stem cells with different roles in tumour progression

Search for Yin-Ping Lu in:Nature Research journals • PubMed • Google Scholar Search for Ahmed Abdelmaksou in:Nature Research journals • PubMed • Google Scholar Search for Min-xuan Sun in:Nature Research

ADMETlab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database

Current pharmaceutical research and development (R&D) is a high-risk investment which is usually faced with some unexpected even disastrous failures in different stages of drug discovery. One main reason for R&D failures is the efficacy and safety deficiencies which are related largely to absorption, distribution, metabolism and excretion (ADME) properties and various toxicities...

A Novel Surface Texture Shape for Directional Friction Control

An experimental study is presented to evaluate the influence of anisotropically shaped textures on the behaviour of sliding friction and sensitivity to sliding direction. The plate samples were textured with triangular sloped dimples using an ultrafast laser surface texturing technique. Reciprocating cylinder-on-plate tests were conducted with steel sliding pairs using mineral...

A new fast heat treatment process for cast A356 alloy motorcycle wheel hubs

The normal T6 heat treatment process for cast A356 alloy generally requires about 15 h. This long-period procedure increases greatly the manufacturing cost and decreases the productivity in practical production. In this study, a new short-time heat treatment process with only 30 min solution time at 540 °C was developed for the production of motorcycle wheel hubs in order to...

Mechanisms of P-Glycoprotein Modulation by Semen Strychni Combined with Radix Paeoniae Alba

Semen Strychni has been extensively used as a Chinese herb, but its therapeutic window is narrowed by the strong toxicity of the compound, which limits its effectiveness. Radix Paeoniae Alba has been reported to reduce the toxic effects and increase the therapeutic effects of Semen Strychni, but the underlying mechanism remains unknown. This research aimed to explore the...

Alginate oligosaccharide indirectly affects toll-like receptor signaling via the inhibition of microRNA-29b in aneurysm patients after endovascular aortic repair

Alginate oligosaccharide indirectly affects toll-like receptor signaling via the inhibition of microRNA-29b in aneurysm patients after endovascular aortic repair Yong Yang,1–4,* Zhenhuan Ma,1–4,* Guokai Yang,1–4 Jia Wan,1–4 Guojian Li,1–4 Lingjuan Du,1–4 Ping Lu1–4 1Department of Vascular Surgery, The Second People’s Hospital of Yunnan Province, Kunming, China; 2Department of...

The Maoxian landslide as seen from space: detecting precursors of failure with Sentinel-1 data

Post-event Interferometric Synthetic Aperture Radar (InSAR) analysis on a stack of 45 C-band SAR images acquired by the ESA Sentinel-1 satellites from 9 October 2014 to 19 June 2017 allowed the identification of a clear precursory deformation signal for the Maoxian landslide (Mao County, Sichuan Province, China). The landslide occurred in the early morning of 24 June 2017 and...

Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats

Conceptualization: Fei Han, Ya-Ping Lu. Data curation: Fei Han, Ting-Ting Zhuang, Jing-Jing Chen, Xiu-Ling Zhu. Formal analysis: Fei Han. Methodology: Fei Han, Ting-Ting Zhuang. Project administration: Fei Han ... , Xiu-Ling Zhu, Ya-Ping Lu. Resources: Ya-Ping Lu. 17 / 24 Visualization: Fei Han. Writing ± original draft: Fei Han, Ya-Ping Lu. Writing ± review & editing: Ya-Fei Cai, Ya-Ping Lu. 18 / 24 19 / 24 20

Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis

AffiliationsDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC, USAMatthew J. Scheffel, Ping Lu, Jacob S. Bowers, Chrystal M. Paulos & Christina Voelkel-JohnsonDepartment of ... Scholar Search for Kristi Helke in:Nature Research journals • PubMed • Google Scholar Search for Ping Lu in:Nature Research journals • PubMed • Google Scholar Search for Jacob S. Bowers in:Nature Research

Cryptosporidium Removal from Runoff by Active Carbon Filter with Coal Gangue

Copyright © 2016 Ping Lu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Cryptosporidium Contamination and Attributed Risks in Yunlong Lake in Xuzhou, China

Technology, Xuzhou 221116, China 3JiangSu Collaborative Innovation Center for Building Energy Saving and Construct Technology, Xuzhou 221116, China Correspondence should be addressed to Ping Lu; moc.621

Cryptosporidium Contamination and Attributed Risks in Yunlong Lake in Xuzhou, China

Technology, Xuzhou 221116, China 3JiangSu Collaborative Innovation Center for Building Energy Saving and Construct Technology, Xuzhou 221116, China Correspondence should be addressed to Ping Lu; moc.621

Study of Ф-OTDR stability for dynamic strain measurement in piezoelectric vibration

In a phase-sensitive optical-time domain reflectometry (Φ-OTDR) system, the challenge for dynamic strain measurement lies in large intensity fluctuations from trace to trace. The intensity fluctuation caused by stochastic characteristics of Rayleigh backscattering sets detection limit for the minimum strength of vibration measurement and causes the large measurement uncertainty...