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Role of DiGeorge syndrome critical region gene 9, a long noncoding RNA, in gastric cancer

Role of DiGeorge syndrome critical region gene 9, a long noncoding RNA, in gastric cancer Chao Ni,1 Ping Yang,1 Junming Guo,1 Meng Ye2 1Department of Biochemistry and Molecular Biology, Zhejiang Key

A nonlinear approach to identify pathological change of thyroid nodules based on statistical analysis of ultrasound RF signals

In order to reassure the majority of patients with benign nodules from unnecessary needle biopsy, there is an increasing clinical requirement to identify benign and malignant thyroid nodules during ultrasound diagnosis. A nonlinear approach based on statistical analysis of ultrasound radio-frequency (RF) signals was developed for differential diagnosing the thyroid nodules to...

Effectiveness of continuous improvement by a clinical pharmacist-led guidance team on the prophylactic antibiotics usage rationality in intervention procedure at a Chinese tertiary teaching hospital

Ping Yang, Sai-Ping Jiang, Xiao-Yang Lu Department of Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China Background: Irrational prophylactic antibiotics

Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells

Chemoresistance remains a major obstacle to successful treatment of breast cancer. Although soluble tumor necrosis factor-α (sTNF-α) has been implicated in mediating drug-resistance in human cancers, whether transmembrane tumor necrosis factor-α (tmTNF-α) plays a role in chemoresistance remains unclear. Here we found that over 50% of studied patients expressed tmTNF-α at high...

The incidence and factors of hip fractures and subsequent morbidity in Taiwan: An 11-year population-based cohort study

: DOH103-HO-1008 and 10501). The authors also thank the National Health Research Institute for providing the data. Author Contributions Conceptualization: Kai-Biao Lin, Nan-Ping Yang, Nien-Tzu Chang. Data ... . Resources: Yi-Hui Lee. Software: Kai-Biao Lin. Supervision: Chi-Hsu Wu. Project administration: Kai-Biao Lin, Nan-Ping Yang, Chien-Lung Chan. Validation: Nan-Ping Yang, Chi-Hsu Wu. Writing ± original

MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis

Ping Yang 0 0 Department of Cardiology, China-Japan Union Hospital of Jilin University , 130033 Changchun , China 1 Department of Ultrasonography, Eastern Division of First Hospital of Jilin University

Successful treatment of angiosarcoma of the scalp with apatinib: a case report

Successful treatment of angiosarcoma of the scalp with apatinib:a case report Guanghui Ji,1 Liu Hong,2 Ping Yang3 1Department of Traditional Chinese Medicine, 2Department of Pathology, 3Department of Oncology, PLA Navy General Hospital, Beijing, People’s Republic of China Abstract: Angiosarcoma is a rare and aggressive vascular malignancy with a poor prognosis. There is no...

The effects of local variation in light availability on pollinator visitation, pollen and resource limitation of female reproduction in Hosta ventricosa

BackgroundLight availability may have direct effects on reproduction through resource availability, and indirect effects on female reproduction by influencing plant-pollinator interactions. Floral display size, pollinator visitation per flower, resource and pollen limitation of fruit and seed production were quantified in a forested patch and an adjacent open patch of two...

Odor selectivity of hyposmia and cognitive impairment in patients with Parkinson’s disease

Odor selectivity of hyposmia and cognitive impairment in patients with Parkinson's disease Cheng-Jie Mao,1 Fen Wang,2 Ju-Ping Chen,3 Ya-Ping Yang,1 Jing Chen,1 Juan-Ying Huang,1 Chun-Feng ... (PAPD). Author contributions Cheng-Jie Mao and Chun-Feng Liu designed the study. Fen Wang, Ju-Ping Chen, Ya-Ping Yang, Jing Chen, and JuanYing Huang collected the data. Cheng-Jie Mao and Fen Wang

Design of robust high-order superdirectivity for circular arrays with sensor gain and phase errors

Though the high-order superdirectivity theory proposed in recent years is attractive, it is hard to implement in practice due to its poor robustness to small random array errors. Hence, in this paper, we present two robust designs of high-order superdirectivity for circular arrays with gain and phase errors. Firstly, we study on the sensitivity function of the high-order...

Lysophosphatidic acid enhances human umbilical cord mesenchymal stem cell viability without differentiation via LPA receptor mediating manner

Human umbilical cord mesenchymal stem cells (hUC-MSCs) are potential stromal cells which are regarded as the most feasible stem cell group in cell therapy. The maintenance of cell survival without differentiation is important in cell transplantation and stem cell therapy. However, negative factors exist in cell transplantation. Lysophosphatidic acid (LPA) is a non-antigenic small...

Inappropriateness of medication prescriptions about chronic kidney disease patients without dialysis therapy in a Chinese tertiary teaching hospital

Inappropriateness of medication prescriptions about chronic kidney disease patients without dialysis therapy in a Chinese tertiary teaching hospital Ping Yang, Na Chen, Rong-Rong Wang, Lu Li, Sai ... . Improving the quality of medication prescriptions in CKD patients is necessary. - Ping Yang n a Chen Rong-Rong Wang l u l i sai-Ping Jiang Introduction Chronic kidney disease (CKD) is defined as

Differential microRNA Expression and Regulation in the Rat Model of Post-Infarction Heart Failure

Background Heart failure is a complex end stage of various cardiovascular diseases with a poor prognosis, and the mechanisms for development and progression of heart failure have always been a hot point. However, the molecular mechanisms underlying the post transcriptional regulation of heart failure have not been fully elucidated. Current data suggest that microRNAs (miRNAs) are...

Power management in adjacent cognitive femtocells with distance-dependent interference in full coverage area

Xin Ao 0 Ping Yang 0 Ming Li 0 0 Department of Electronic Engineering, Dongguan University of Technology , Daxue Road, Dongguan , China In cognitive heterogeneous networks, when multiple adjacent

Elevated Cellular PD1/PD-L1 Expression Confers Acquired Resistance to Cisplatin in Small Cell Lung Cancer Cells

Although small cell lung cancer (SCLC) is highly responsive to chemotherapies (e.g., cisplatin-etoposide doublet), virtually almost all responsive SCLC patients experience disease recurrence characterized by drug resistance. The mechanisms underlying cisplatin resistance remain elusive. Here we report that cell-intrinsic expression of PD1 and PD-L1, two immune checkpoints, is...

Genome-Wide Transcriptome Analysis of CD36 Overexpression in HepG2.2.15 Cells to Explore Its Regulatory Role in Metabolism and the Hepatitis B Virus Life Cycle

Hepatitis B virus (HBV) is a hepatocyte-specific DNA virus whose gene expression and replication are closely associated with hepatic metabolic processes. Thus, a potential anti-viral strategy is to target the host metabolic factors necessary for HBV gene expression and replication. Recent studies revealed that fatty acid translocase CD36 is involved in the replication, assembly...

Effects of Scleroderma sichuanensis Xiao (Hymenoptera: Bethylidae) venom and parasitism on nutritional content regulation in host Tenebrio molitor L. (Coleoptera: Tenebrionidae)

To explore the mechanisms by which the wasp Scleroderma sichuanensis Xiao regulates the physiology and biochemistry of its host, effects of S. sichuanensis venom and parasitism on host the Tenebrio molitor L. pupae were examined. Significant differences in nutritional content were noted between parasitized and non-parasitized pupae and between venom- and phosphate buffered saline...

Changes of flowering phenology and flower size in rosaceous plants from a biodiversity hotspot in the past century

Responses of plant traits to climate changes are complex, which could be mirrored by the investigations of herbarium specimens. By examining specimens of Rosa and Cotoneaster species collected since 1920s in Hengduan Mountains, we analyzed the changes of flowering phenology and flower size in the past century when climate changes were considered to be intensified. We found that...

Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function

Aims/hypothesisPost-translational attachment of a small ubiquitin-like modifier (SUMO) to the lysine (K) residue(s) of target proteins (SUMOylation) is an evolutionary conserved regulatory mechanism. This modification has previously been demonstrated to be implicated in the control of a remarkably versatile regulatory mechanism of cellular processes. However, the exact regulatory...

The Biogeographic South-North Divide of Polygonatum (Asparagaceae Tribe Polygonateae) within Eastern Asia and Its Recent Dispersals in the Northern Hemisphere

Eastern Asia (EA) is a key region for the diversification of flowering plants in the Northern Hemisphere, but few studies have focused on the biogeographic history within EA in the context of the other northern continents. Polygonatum is an important medicinal genus widely distributed in the Northern Hemisphere with its highest species richness in EA, and it represents an...