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-Omics and Prognostic Markers

, Yuanyuan Xiao 2, Amanda L. Rynearson 1, Stephanie Fink 1, Matthew L. Kosel 1, Derek R. Johnson 1, Daniel H. Lachance 1, Ping Yang 1, Brooke L.Fridley 1, JosephWiemels 2, JohnWiencke 2, and Robert B.Jenkins 1 ... HYBRIDIZATION Stephanie Fink , Thomas Kollmeyer , Amanda Rynearson , Paul Decker , Hugues Sicotte , Ping Yang , and Robert Jenkins ; Mayo Clinic BACKGROUND: Glioblastoma multiforme (GBM) is the most common and

A CBA-KELM-Based Recognition Method for Fault Diagnosis of Wind Turbines with Time-Domain Analysis and Multisensor Data Fusion

Fault diagnosis technology (FDT) is an effective tool to ensure stability and reliable operation in wind turbines. In this paper, a novel fault diagnosis methodology based on a cloud bat algorithm (CBA)-kernel extreme learning machines (KELM) approach for wind turbines is proposed via combination of the multisensor data fusion technique and time-domain analysis. First, the...

A Direct Interaction Between EXT Proteins and Glycosyltransferases is Defective in Hereditary Multiple Exostoses

Hereditary multiple exostoses (HME) is an autosomal dominant condition in which bony outgrowths occur from the juxtaepiphyseal regions of the long bones. In a few percent of cases these exostoses undergo malignant transformation to chondrosarcomas. HME results from mutations in one of two homologous genes, EXT1 and EXT2. These are members of a new gene family that is conserved...

A Gene Expression Signature Predicts Survival of Patients with Stage I Non-Small Cell Lung Cancer

Background Lung cancer is the leading cause of cancer-related death in the United States. Nearly 50% of patients with stages I and II non-small cell lung cancer (NSCLC) will die from recurrent disease despite surgical resection. No reliable clinical or molecular predictors are currently available for identifying those at high risk for developing recurrent disease. As a...

A New Tumor Suppressor DnaJ-like Heat Shock Protein, HLJ1, and Survival of Patients With Non–Small-Cell Lung Carcinoma

Background: We previously identified DnaJ-like heat shock protein (HLJ1) as a gene associated with tumor invasion. Here, we investigated the clinical significance of HLJ1 expression in non–small-cell lung cancer (NSCLC) patients and its role in cancer progression. Methods: We induced HLJ1 overexpression or knockdown in human lung adenocarcinoma CL1–5 cells and analyzed cell...

A Proposal for Realizing a 3-Qubit Controlled-Phase Gate with Superconducting Qubit Systems Coupled to a Cavity

Chui-Ping Yang 0 1 Subject Index: 0 State Key Laboratory of Precision Spectroscopy, Department of Physics, East China Normal University , Shanghai 200062, China 1 Department of Physics, Hangzhou

A Randomized, Double Blind, Placebo-Controlled, Multicenter Phase II Trial of Allisartan Isoproxil in Essential Hypertensive Population at Low-Medium Risk

Background Angiotensin II receptor blockers (ARBs) is a well-tolerated class of antihypertensive agents, exhibiting effective antihypertensive and cardiovascular protective function. The objective of the study was to examine the efficacy and safety of Allisartan Isoproxil, a newly developed, selective, nonpeptide blocker of the angiotensin II type 1 receptor (AT1R), in essential...

A Sensitivity-Based Improving Learning Algorithm for Madaline Rule II

This paper proposes a new adaptive learning algorithm for Madalines based on a sensitivity measure that is established to investigate the effect of a Madaline weight adaptation on its output. The algorithm, following the basic idea of minimal disturbance as the MRII did, introduces an adaptation selection rule by means of the sensitivity measure to more accurately locate the...

A Sensitivity-Based Improving Learning Algorithm for Madaline Rule II

This paper proposes a new adaptive learning algorithm for Madalines based on a sensitivity measure that is established to investigate the effect of a Madaline weight adaptation on its output. The algorithm, following the basic idea of minimal disturbance as the MRII did, introduces an adaptation selection rule by means of the sensitivity measure to more accurately locate the...

A Study of the Effects of Daily Physical Activity on Memory and Attention Capacities in College Students

This study evaluated the relationship between daily physical activity (DPA) and memory capacity, as well as the association between daily activity and attention capacity, in college students in Taiwan. Participants (mean age = 20.79) wore wearable trackers for 106 days in order to collect DPA. These data were analyzed in association with their memory and attention capacities, as...

A Study of the Effects of Daily Physical Activity on Memory and Attention Capacities in College Students

This study evaluated the relationship between daily physical activity (DPA) and memory capacity, as well as the association between daily activity and attention capacity, in college students in Taiwan. Participants (mean age = 20.79) wore wearable trackers for 106 days in order to collect DPA. These data were analyzed in association with their memory and attention capacities, as...

A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease

-zhu Peng 0 Ping Yang 5 Ming-qing Chen 4 Yun Gu 0 0 Department of Cardiology, 1st Hospital of Kunming Medical University , Kunming, Yunnan, PRC 1 Department of Cardiology, Cardiovascular Center, 1st ... -Ming Tao, Yun-Zhu Peng, Ping Yang performed research/ study, Dr. Tie-Kun Ma, Hong-Yan Cai contributed important reagents, Dr. Yu Wang, Tao Guo managed the literature searches and analyses, Dr. Yu Wang

A new method for the assessment of endothelial function with peripheral arterial volume

interests Author Ping Yang has been a consultant for Saintyear Medical Ltd., which owns patent rights to PAV technique. Other authors have nothing to disclose. Publisher’s Note Springer Nature remains

A nonlinear approach to identify pathological change of thyroid nodules based on statistical analysis of ultrasound RF signals

In order to reassure the majority of patients with benign nodules from unnecessary needle biopsy, there is an increasing clinical requirement to identify benign and malignant thyroid nodules during ultrasound diagnosis. A nonlinear approach based on statistical analysis of ultrasound radio-frequency (RF) signals was developed for differential diagnosing the thyroid nodules to...

A quasi-experimental study on a quality circle program in a Taiwanese hospital

Objective. To explore the impact of quality circles on job satisfaction, absenteeism, and turnover among hospital nurses in Taiwan. Design. A quasi-experimental research design. Setting. In November 1995, a study was initiated to establish quality circles in a 500-bed community hospital in Taiwan. After the administrative process and a pilot study, three of the experimental units...

A sequence polymorphism on 8q24 is associated with survival in hepatocellular carcinoma patients who received radiation therapy

information AffiliationsDepartments of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, ChinaXiao-Mei Zhao, Zuo-Lin Xiang, Yi-Xing Chen, Ping Yang, Yong Hu & Zhao-Chong Zeng AuthorsSearch for ... • PubMed • Google Scholar Search for Ping Yang in:Nature Research journals • PubMed • Google Scholar Search for Yong Hu in:Nature Research journals • PubMed • Google Scholar Search for Zhao-Chong Zeng

A simple and convenient method for the preparation of antioxidant peptides from walnut (Juglans regia L.) protein hydrolysates

Background Walnut (Juglans regia L.), that belongs to the Juglandaceae family, is one of the nuts commonly found in Chinese diets. Researchers had obtained peptides from walnut protein hydrolysates, and these peptides exhibited the high antioxidant activities. The objective of this study was to develop a simple and convenient method for a facile and reproducible preparation of...

Aberrant Expression of miR-638 Contributes to Benzo(a)pyrene-Induced Human Cell Transformation

Identification of aberrant microRNA (miRNA) expression during chemical carcinogen–induced cell transformation will lead to a better understanding of the substantial role of miRNAs in cancer development. To explore whether aberrant miRNAs expression can be used as biomarkers of chemical exposure in risk assessment of chemical carcinogenesis, we analyzed miRNA expression profiles...

Activation of CD137 Signaling Enhances Vascular Calcification through c-Jun N-Terminal Kinase-Dependent Disruption of Autophagic Flux

Background. Vascular calcification is widespread and clinically significant, contributing to substantial morbidity and mortality. Calcifying vascular cells are partly derived from local vascular smooth muscle cells (VSMCs), which can undergo chondrogenic or osteogenic differentiation under inflammatory environment. Recently, we have found activation of CD137 signaling accelerated...

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice

Transient receptor potential canonical (TRPC) channels are widely expressed in brain and involved in various aspects of brain function. Both TRPC4 and TRPC5 have been implicated in innate fear function, which represents a key response to environmental stress. However, to what extent the TRPC4/C5 channels are involved in psychiatric disorders remains unexplored. Here, we tested...