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Osteopetrosis in two siblings: two case reports

Background Osteopetrosis is a rare inherited metabolic bone disorder characterized by extensive sclerosis of skeletons, visual and hearing impairment, hepatosplenomegaly and anemia. It has two major clinical forms: the autosomal dominant adult (benign) form is associated with milder symptoms often appearing in later childhood and adulthood whereas the autosomal recessive...

Overexpression of a fusion defensin gene from radish and fenugreek improvesresistance against leaf spot diseases caused by Cercospora arachidicola and Phaeoisariopsis personata in peanut

Peanut (Arachis hypogaea L.) is one of the important oilseed crops of the Indian subcontinent and fungal diseases like early leaf spot (ELS) and late leaf spot (LLS) caused by Cercospora arachidicola and Phaeoisariopsis personata, respectively, are major peanut cultivation constraints. Defensins are basically antimicrobial peptides that have been implicated in plant defense...

Necrotizing Soft Tissue Infections: Surgeon’s Prospective

University, Varanasi 221005, India Received 26 June 2013; Revised 8 September 2013; Accepted 11 October 2013 Academic Editor: Jonathan Steven Alexander Copyright © 2013 Shashi Prakash Mishra et al. This

Tailor-Made Pentablock Copolymer Based Formulation for Sustained Ocular Delivery of Protein Therapeutics

The objective of this research article is to report the synthesis and evaluation of novel pentablock copolymers for controlled delivery of macromolecules in the treatment of posterior segment diseases. Novel biodegradable PB copolymers were synthesized by sequential ring-opening polymerization. Various ratios and molecular weights of each block (polyglycolic acid, polyethylene...

Overexpression of Bacterial mtlD Gene in Peanut Improves Drought Tolerance through Accumulation of Mannitol

In the changing global environmental scenarios, water scarcity and recurrent drought impose huge reductions to the peanut (Arachis hypogaea L.) crop yield. In plants, osmotic adjustments associated with efficient free radical scavenging ability during abiotic stress are important components of stress tolerance mechanisms. Mannitol, a compatible solute, is known to scavenge...

An Unusual Presentation of Ovarian Teratoma: A Case Report

Mature cystic teratomas account for 10–20% of all ovarian neoplasms and are the most common neoplasm in younger patients. Spontaneous rupture of the teratoma is rare and has been occasionally reported. Here we present an unusual case of left ovarian teratoma rupturing into sigmoid colon.

An Unusual Presentation of Ovarian Teratoma: A Case Report

Mature cystic teratomas account for 10–20% of all ovarian neoplasms and are the most common neoplasm in younger patients. Spontaneous rupture of the teratoma is rare and has been occasionally reported. Here we present an unusual case of left ovarian teratoma rupturing into sigmoid colon.

Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites

Background Ribosome biogenesis is an energy consuming and stringently controlled process that involves hundreds of trans-acting factors. Small nucleolar RNAs (snoRNAs), important components of ribosome biogenesis are non-coding guide RNAs involved in rRNA processing, nucleotide modifications like 2'-O-ribose methylation, pseudouridylation and possibly gene regulation. snoRNAs are...