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Free-space creation of ultralong anti-diffracting beam with multiple energy oscillations adjusted using optical pen

A light beam propagating over an infinite anti-diffracting distance requires infinite power to preserve its shape. However, the fundamental barrier of finite power in free space has made the problem of diffraction insurmountable in recent decades. To overcome this limitation, we report an approach that employs the multiple energy oscillation mechanism, thereby permitting the...

Zuo Gui Wan Alters Expression of Energy Metabolism Genes and Prevents Cell Death in High-Glucose Loaded Mouse Embryos

Wang,1 Qiang Song,1 and David L. Adelson2 1Shanxi University of Chinese Medicine, Taiyuan 030619, China 2School of Biological Sciences, University of Adelaide, Adelaide, SA 5005, Australia 3Beijing ... University of Chinese Medicine, Beijing 100029, China Correspondence should be addressed to Qiang Song; moc.361@44884643831 and David L. Adelson; ua.ude.edialeda@nosleda.divad Received 7 December 2017

Zuo Gui Wan Alters Expression of Energy Metabolism Genes and Prevents Cell Death in High-Glucose Loaded Mouse Embryos

Wang,1 Qiang Song,1 and David L. Adelson2 1Shanxi University of Chinese Medicine, Taiyuan 030619, China 2School of Biological Sciences, University of Adelaide, Adelaide, SA 5005, Australia 3Beijing ... University of Chinese Medicine, Beijing 100029, China Correspondence should be addressed to Qiang Song; moc.361@44884643831 and David L. Adelson; ua.ude.edialeda@nosleda.divad Received 7 December 2017

PyHLA: tests for the association between HLA alleles and diseases

Background Recently, several tools have been designed for human leukocyte antigen (HLA) typing using single nucleotide polymorphism (SNP) array and next-generation sequencing (NGS) data. These tools provide high-throughput and cost-effective approaches for identifying HLA types. Therefore, tools for downstream association analysis are highly desirable. Although several tools have...

DMBA acts on cumulus cells to desynchronize nuclear and cytoplasmic maturation of pig oocytes

As an environmental pollutant and carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) can destroy ovarian follicles at all developmental stages in rodents. However, the underlying molecular mechanism remains obscure. In the present study, we aim to address how DMBA affects the in vitro maturation and development of porcine oocytes. We discovered that for 20 μM DMBA-treated cumulus...

Experimental Study on the Influence of DPF Micropore Structure and Particle Property on Its Filtration Process

A single layer filtration system was developed to investigate the filtration and regeneration performance of diesel particle filter (DPF). The particle layer thickness was directly measured online to analyze the different filtration stages. The influence of particle property on particle layer stage performance was also investigated. The results indicate that the filtration...

Experimental Study on the Influence of DPF Micropore Structure and Particle Property on Its Filtration Process

A single layer filtration system was developed to investigate the filtration and regeneration performance of diesel particle filter (DPF). The particle layer thickness was directly measured online to analyze the different filtration stages. The influence of particle property on particle layer stage performance was also investigated. The results indicate that the filtration...

Neural Hyperactivity of the Central Auditory System in Response to Peripheral Damage

It is increasingly appreciated that cochlear pathology is accompanied by adaptive responses in the central auditory system. The cause of cochlear pathology varies widely, and it seems that few commonalities can be drawn. In fact, despite intricate internal neuroplasticity and diverse external symptoms, several classical injury models provide a feasible path to locate responses to...

Neural Hyperactivity of the Central Auditory System in Response to Peripheral Damage

It is increasingly appreciated that cochlear pathology is accompanied by adaptive responses in the central auditory system. The cause of cochlear pathology varies widely, and it seems that few commonalities can be drawn. In fact, despite intricate internal neuroplasticity and diverse external symptoms, several classical injury models provide a feasible path to locate responses to...

Dynamic Modeling and Control Strategy Optimization for a Hybrid Electric Tracked Vehicle

A new hybrid electric tracked bulldozer composed of an engine generator, two driving motors, and an ultracapacitor is put forward, which can provide high efficiencies and less fuel consumption comparing with traditional ones. This paper first presents the terramechanics of this hybrid electric tracked bulldozer. The driving dynamics for this tracked bulldozer is then analyzed...

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis (AIS) is the most common type of spinal deformity and has a significant genetic background. Genome-wide association studies (GWASs) identified several susceptibility loci associated with AIS. Among them is a locus on chromosome 6q24.1 that we identified by a GWAS in a Japanese cohort. The locus is represented by rs6570507 located within GPR126. To...

Dimethyl Sulfoxide Perturbs Cell Cycle Progression and Spindle Organization in Porcine Meiotic Oocytes

Meiotic maturation of mammalian oocytes is a precisely orchestrated and complex process. Dimethyl sulfoxide (DMSO), a widely used solvent, drug, and cryoprotectant, is capable of disturbing asymmetric cytokinesis of oocyte meiosis in mice. However, in pigs, DMSO’s effect on oocyte meiosis still remains unknown. We aimed to evaluate if DMSO treatment will affect porcine oocyte...

Mass production of bulk artificial nacre with excellent mechanical properties

Various methods have been exploited to replicate nacre features into artificial structural materials with impressive structural and mechanical similarity. However, it is still very challenging to produce nacre-mimetics in three-dimensional bulk form, especially for further scale-up. Herein, we demonstrate that large-sized, three-dimensional bulk artificial nacre with...

Inflammation in Alzheimer’s Disease and Molecular Genetics: Recent Update

Alzheimer’s disease (AD) is a complex age-related neurodegenerative disorder of the central nervous system. Since the first description of AD in 1907, many hypotheses have been established to explain its causes. The inflammation theory is one of them. Pathological and biochemical studies of brains from AD individuals have provided solid evidence of the activation of inflammatory...

Separation of Hepatic Iron and Fat by Dual-Source Dual-Energy Computed Tomography Based on Material Decomposition: An Animal Study

Objective To explore the feasibility of dual-source dual-energy computed tomography (DSDECT) for hepatic iron and fat separation in vivo. Materials and Methods All of the procedures in this study were approved by the Research Animal Resource Center of Shanghai Ruijin Hospital. Sixty rats that underwent DECT scanning were divided into the normal group, fatty liver group, liver...

Protective effects of alginate–chitosan microspheres loaded with alkaloids from Coptis chinensis Franch. and Evodia rutaecarpa (Juss.) Benth. (Zuojin Pill) against ethanol-induced acute gastric mucosal injury in rats

mucosal injury in rats Qiang-Song Wang,1,2,* Xiao-Ning Zhu,1,* Heng-Li Jiang,1,* Gui-Fang Wang,3 Yuan-Lu Cui1 1Tianjin State Key Laboratory of Modern Chinese Medicine, Research Center of Traditional Chinese

PExFInS: An Integrative Post-GWAS Explorer for Functional Indels and SNPs

for Cun Li in:Nature Research journals • PubMed • Google ScholarSearch for You-Qiang Song in:Nature Research journals • PubMed • Google ScholarSearch for Jie Zhou in:Nature Research journals • PubMed

A γA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid

Cataract is the most common cause of visual loss in humans. A spontaneously occurred, autosomal dominant mouse mutant Secc, which displayed combined features of small eye, cataract and closed eyelid was discovered in our laboratory. In this study, we identified the mutation and characterized the cataract phenotype of this novel Secc mutant. The Secc mutant mice have eyelids that...