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Dominant patterns of winter-time intraseasonal surface air temperature over the CONUS in response to MJO convections

The dominant patterns of the intraseasonal surface air temperature (SAT) over the Contiguous United States (CONUS) during wintertime (December–March) are investigated in the period of 1979–2014 in the present study. The first two leading modes revealed by the empirical orthogonal function (EOF) analysis sufficiently represent the patterns by explaining nearly 80% of the total...

Child nutrition to new stage in China: evidence from a series of national surveys, 1985–2015

Both child under- and over-nutrition are major global public health challenges. We aimed to examine thirty-year trends in physical growth, under- and over-nutrition in Chinese urban and suburban children between 1985 and 2015, and discuss implications for child health programmes. A total of 610,785 urban and suburban children from birth to 7 years of age were collected from a...

Hypocoagulation induced by broad-spectrum antibiotics in extensive burn patients

BackgroundPatients with extensive burns usually develop pro-coagulation soon after the injury if there is no sepsis occurred. We describe the case of an extensive burn adult suffering from hypocoagulation not related to sepsis, but secondary to antibiotic treatment.Case presentationHere, we report a case of an adult male patient suffering from flame burns of 45% total body...

Discovery and validation of DNA methylation markers for overall survival prognosis in patients with thymic epithelial tumors

BackgroundThe current prognosis of thymic epithelial tumors (TETs) is according to the World Health Organization (WHO) histologic classification and the Masaoka staging system. These methods of prognosis have certain limitations in clinical application and there is a need to seek new method for determining the prognosis of patients with TETs. To date, there have been no studies...

Rediscovery of Monotropastrum sciaphilum (Andres) G.D.Wallace in China after 91 Years

MONOTROPASTRUM SCIAPHILUM (ANDRES) G.D.WALLACE IN CHINA AFTER 91 YEARS MIN SHEN,1,2,3 CHANG-QIN ZHANG,1,5 AND GARY D. WALLACE4 1Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China

Reduced Sensitivity of Older Adults to Affective Mismatches

The present study investigated age-related differences in emotional processing by using a paradigm of affective priming. Eighteen, right-handed, younger (mean age 22) and 15 older (mean age 68) subjects pressed buttons to indicate pleasantness of target words. The valence of each prime-target pair was congruent (e.g., win-love), incongruent (e.g., love-loss), or neutral (time...

Ensemble learning particle swarm optimization for real-time UWB indoor localization

This paper presents an ensemble learning particle swarm optimization (ELPSO) algorithm for real-time indoor localization based on ultra-wideband (UWB). Indoor localization problem can be formulated as an optimization problem to predict the target. The proposed algorithm expands the original PSO into ELPSO under superbest guide, which is a parameter employed to identify the top...

Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency

BackgroundMouse somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors known to regulate pluripotency, including Oct4, Sox2, Klf4, and c-Myc. It has been reported that Sirtuin 6 (Sirt6), a member of the sirtuin family of NAD+-dependent protein deacetylases, is involved in embryonic stem cell differentiation. However, whether and how Sirt6...

Meta-analysis of the association between the inflammatory potential of diet and urologic cancer risk

Zhang, Bo Yang. Methodology: Zheng-Ju Ren, Peng-Wei Ren. 9 / 12 Software: Peng-Wei Ren. Supervision: Liang-Ren Liu, Qiang Dong. Writing ? original draft: Dong-Liang Lu, Zheng-Ju Ren, Qin Zhang. Writing ... S1 Checklist. PRISMA checklist for this meta-analysis. (DOC) S1 Fig. Flowchart showing study selection. (DOC) Author Contributions Conceptualization: Dong-Liang Lu, Zheng-Ju Ren. Data curation: Qin

Equivalent Viscous Damping Ratio Model for Flexure Critical Reinforced Concrete Columns

In order to determine the energy dissipation capacity of flexure critical reinforced concrete (RC) columns reasonably, an expression for describing the hysteretic behavior including loading and unloading characteristics of flexure critical RC columns is presented, and then, a new equivalent viscous damping (EVD) ratio model including its simplified format, which is interpreted as...

Sema3a inhibits the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing inflammation

. Investigation: Qin Zhang. Methodology: Bo Huang, Kun He, Yan Huang. Project administration: Bo Huang, Yan Huang, Hua Tang, Ping Gong. Resources: Bo Huang. 16 / 18 Software: Kun He. Writing ? original draft: Bo

Spatial Differencing Reconstruction Based Low-Angle DOA Estimation with MIMO Radar

Due to the multipath effect, the direction of arrival (DOA) estimation performance for low-angle targets decreases greatly. To overcome this problem, this paper proposes a spatial differencing reconstruction based DOA estimation algorithm by using the received signal model of multiple input multiple output (MIMO) radar. Combining with the spatial diversity of MIMO radar, the...

Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition

Calpains are intracellular calcium-dependent cysteine proteases, which cleave several substrates proteins, have been proven to play important roles in lung fibrosis. The aim of this study was to investigate the effects of calpain on bleomycin (BLM)-induced pulmonary fibrosis. A lung fibrosis mice model was established successfully by intraperitoneal injection of bleomycin...

Expanding the BLUP alphabet for genomic prediction adaptable to the genetic architectures of complex traits

Improvement of statistical methods is crucial for realizing the potential of increasingly dense genetic markers. Bayesian methods treat all markers as random effects, exhibit an advantage on dense markers, and offer the flexibility of using different priors. In contrast, genomic best linear unbiased prediction (gBLUP) is superior in computing speed, but only superior in...

Combination of Multifocal Electroretinogram and Spectral-Domain OCT Can Increase Diagnostic Efficacy of Parkinson’s Disease

Background. The retinal changes have been identified in morphology and function in Parkinson’s disease (PD). However, the controversial results suggest that it is incredible that only using a single method for testing retinal change to evaluate Parkinson’s disease. The aim of this study was to assess retinal changes and increase the diagnostic efficacy of Parkinson’s disease with...

Combination of Multifocal Electroretinogram and Spectral-Domain OCT Can Increase Diagnostic Efficacy of Parkinson’s Disease

Background. The retinal changes have been identified in morphology and function in Parkinson’s disease (PD). However, the controversial results suggest that it is incredible that only using a single method for testing retinal change to evaluate Parkinson’s disease. The aim of this study was to assess retinal changes and increase the diagnostic efficacy of Parkinson’s disease with...

Serum uric acid levels in patients with amyotrophic lateral sclerosis: a meta-analysis

The pathogenic mechanism of ALS remains unclear. However, increasing evidence has indicated that uric acid (UA) may play a protective role in the pathogenesis of ALS. The aim of this study was to evaluate the association between serum UA levels and ALS. A comprehensive literature search in PubMed, Embase, Web of Science, and Cochrane Library was conducted up to 31st August, 2017...

Layout Planning of Multimodal Transport Center in Ji'nan

With the development of economy, efficient organization and transportation are increasingly sought after by people. The comprehensive freight system is the direction of future development. Multimodal transport is a large system composed of a combination of multiple modes of transport. It is a new form of transport organization. In the context of economic globalization, multimodal...

Regulation of DNA methylation on EEF1D and RPL8 expression in cattle

Dynamic changes to the epigenome play a critical role in a variety of biology processes and complex traits. Many important candidate genes have been identified through our previous genome wide association study (GWAS) on milk production traits in dairy cattle. However, the underlying mechanism of candidate genes have not yet been clearly understood. In this study, we analyzed the...

Computational screening of high-performance optoelectronic materials using OptB88vdW and TB-mBJ formalisms

We perform high-throughput density functional theory (DFT) calculations for optoelectronic properties (electronic bandgap and frequency dependent dielectric function) using the OptB88vdW functional (OPT) and the Tran-Blaha modified Becke Johnson potential (MBJ). This data is distributed publicly through JARVIS-DFT database. We used this data to evaluate the differences between...