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Search: authors:"Qing Wang"

4 papers found.
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Higgsphobic and fermiophobic Z’ as a single dark matter candidate

Abstract A spin-1 Z’ particle as a single dark matter candidate is investigated by assuming that it does not directly couple to the Higgs boson and standard model fermions and does not mix with the photon and Z boson. The remaining dominant vertices are quartic Z ′ Z ′ ZZ and Z ′ Z ′ W + W −, which can induce effective \( {Z^{\prime }}{Z^{\prime }}q\overline{q} \) couplings...

UMD-MLH1/MSH2/MSH6 databases: description and analysis of genetic variations in French Lynch syndrome families

Lynch syndrome is an autosomal dominant disease caused by germ line heterozygous mutations mainly involving the MSH2, MLH1 and MSH6 genes that belong to the DNA MisMatch Repair (MMR) genes family. The French network counting the 16 licensed laboratories involved in Lynch syndrome genetic testing developed three locus-specific databases with the UMD® software (www.umd.be/MLH1...

Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery

Background Conventional treatment for locally advanced rectal cancer usually combines neoadjuvant radiochemotherapy and surgery. Until recently, there have been limited predictive factors (clinical or biological) for rectal tumor response to conventional treatment. KRAS, BRAF and PIK3CA mutations are commonly found in colon cancers. In this study, we aimed to determine the...

Dengue virus serotype infection specifies the activation of the unfolded protein response

Background Dengue and Dengue hemorrhagic fever have emerged as some of the most important mosquito-borne viral diseases in the tropics. The mechanisms of pathogenesis of Dengue remain elusive. Recently, virus-induced apoptosis mediated by the Unfolded Protein Response (UPR) has been hypothesised to represent a crucial pathogenic event in viral infection. In an attempt to evaluate...