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Corrigendum: Vesicle Size Regulates Nanotube Formation in the Cell

Scientiifc Reports Corrigendum: Vesicle size Regulates Nanotube Formation in the Cell Qian p eter su Wanqing Du Qinghua Ji Boxin Xue Dong Jiang Yueyao Zhu He Ren Chuanmao Zhang Jizhong Lou Yujie sun

The conformational states of talin autoinhibition complex and its activation under forces

Talin is an integrin-binding protein located at focal adhesion site and serves as both an adapter and a force transmitter. Its integrin binding activity is regulated by the intramolecular autoinhibition interaction between its F3 and RS domains. Here, we used atomic force microscopy to measure the strength of talin autoinhibition complex. Our results suggest that the lifetime of...

Vesicle Size Regulates Nanotube Formation in the Cell

for Wanqing Du in:Nature Research journals • PubMed • Google ScholarSearch for Qinghua Ji in:Nature Research journals • PubMed • Google ScholarSearch for Boxin Xue in:Nature Research journals • PubMed

The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

B lymphocytes use B cell receptors (BCRs) to sense the physical features of the antigens. However, the sensitivity and threshold for the activation of BCRs resulting from the stimulation by mechanical forces are unknown. Here we addressed this question using a double-stranded DNA based tension gauge tether system serving as a predefined mechanical force gauge ranging from 12 to...