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94 papers found.
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Dose-independent influence of metoprolol on cardiac and motor functions, QoL, and mental status in Chinese patients with CHF

Dose-independent influence of metoprolol on cardiac and motor functions, QoL, and mental status in Chinese patients with CHF Qian Zhang, Qiuhong Shu, Liyong Wu, Ran Zhang, Yong Meng Department of

Complementary relation of quantum coherence and quantum correlations in multiple measurements

Quantum coherence and quantum correlations lie in the center of quantum information science, since they both are considered as fundamental reasons for significant features of quantum mechanics different from classical mechanics. We present a group of complementary relations for quantum coherence and quantum correlations; specifically, we focus on thermal discord and conditional...

Impact of mesoscale eddies on chlorophyll variability off the coast of Chile

Contributions Conceptualization: Fei Chai. Methodology: Yuntao Wang. Validation: Hao-Ran Zhang. Visualization: Yeping Yuan. Investigation: Yuntao Wang, Hao-Ran Zhang. Writing ± review & editing: Yeping Yuan

Amygdala functional connectivity in female patients with major depressive disorder with and without suicidal ideation

Major depressive disorder (MDD) is a known major risk factor for suicide and is one of the most common mental disorders. Meanwhile, gender differences in suicidal behavior have long been recognized including the finding that women have higher rates of suicidal ideation and/or suicidal behavior than men. The mechanism underlying suicide ideation in female patients with MDD remains...

Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides

Background. Ganoderma lucidum polysaccharides (GLP) has anti-inflammatory and immunomodulatory effects. Dysregulated immune responses are involved in the pathogenesis of dextran sulfate sodium (DSS)-induced colitis. The aim of this study was to assess the therapeutic potential of GLP to alleviate DSS-induced colitis. Methods. The mice were administered with GLP by intragastric...

Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells

Mature human hepatocytes are critical in preclinical research and therapy for liver disease, but are difficult to manipulate and expand in vitro. Hepatic stem cells (HpSCs) may be an alternative source of functional hepatocytes for cell therapy and disease modeling. Since these cells play an import role in regenerative medicine, the precise characterization that determines...

Screen and Verification for Transgene Integration Sites in Pigs

Efficient transgene expression in recipient cells constitutes the primary step in gene therapy. However, random integration in host genome comprises too many uncertainties. Our study presents a strategy combining bioinformatics and functional verification to find transgene integration sites in pig genome. Using an in silico approach, we screen out two candidate sites, namely...

Evaluating CCS Investment of China by a Novel Real Option-Based Model

Carbon capture and storage (CCS) technology is an effective method to mitigate CO2 emission pressure; however it is hard to be evaluated due to uncertainties. This paper establishes a real options analysis (ROA) model to evaluate CCS investment from the perspective of the existing thermal power plant by considering the fluctuations of electricity price, carbon price, and thermal...

A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS

Sepsis, a systemic inflammatory response to infection, is the leading cause of death in the intensive care unit (ICU). Previous studies indicated that mesenchymal stromal cells (MSCs) might have therapeutic potential against sepsis. The current study was designed to investigate the effects of MSCs on sepsis and the underlying mechanisms focusing on inflammasome activation in...

A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS

,1,2 Hao Wu,3 Dong Han,4 Sai Ma,4 Wensi Fan,4 Yabin Wang,1 Ran Zhang,1 Miaomiao Fan,4 Yuesheng Huang,5 Xiaobing Fu,1 and Feng Cao1 1Department of Cardiology & National Clinical Research Center of

Genome-wide analysis of structural variants reveals genetic differences in Chinese pigs

Wang, Chunyuan Zhang. Funding acquisition: Ran Zhang, Yiqiang Zhao, Xiaoxiang Hu. Investigation: Ruifei Yang, Suyun Fang, Jing Wang, Chunyuan Zhang. Methodology: Ruifei Yang. 14 / 18 Project ... administration: Ruifei Yang, Ran Zhang, Di Liu, Yiqiang Zhao, Xiaoxiang Hu, Ning Li. Supervision: Ran Zhang, Di Liu, Yiqiang Zhao, Xiaoxiang Hu, Ning Li. Visualization: Ruifei Yang. Writing ± original draft

An MILP approach for detailed scheduling of oil depots along a multi-product pipeline

Oil depots along products pipelines are important components of the pipeline transportation system and down-stream markets. The operating costs of oil depots account for a large proportion of the total system’s operating costs. Meanwhile, oil depots and pipelines form an entire system, and each operation in a single oil depot may have influence on others. It is a tough job to...

Induction regimens for transplant-eligible patients with newly diagnosed multiple myeloma: a network meta-analysis of randomized controlled trials

Ran Zhang,1,2 Ling-Fei Xiao,1,2 Xiang-Yu Meng1,2 1Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, 2Department of Evidence-Based Medicine and Clinical

Altered visual cortical processing in a mouse model of MECP2 duplication syndrome

As an epigenetic modulator of gene expression, Methyl-CpG binding protein 2 (MeCP2) is essential for normal neurological function. Dysfunction of MeCP2 is associated with a variety of neurological disorders. MECP2 gene duplication in human causes neuropsychiatric symptoms such as mental retardation and autism. MeCP2 overexpression in mice results in neurobehavioural disorders...

A precise and consistent assay for major wall polymer features that distinctively determine biomass saccharification in transgenic rice by near-infrared spectroscopy

The genetic modification of plant cell walls has been considered to reduce lignocellulose recalcitrance in bioenergy crops. As a result, it is important to develop a precise and rapid assay for the major wall polymer features that affect biomass saccharification in a large population of transgenic plants. In this study, we collected a total of 246 transgenic rice plants that...

A precise and consistent assay for major wall polymer features that distinctively determine biomass saccharification in transgenic rice by near-infrared spectroscopy

The genetic modification of plant cell walls has been considered to reduce lignocellulose recalcitrance in bioenergy crops. As a result, it is important to develop a precise and rapid assay for the major wall polymer features that affect biomass saccharification in a large population of transgenic plants. In this study, we collected a total of 246 transgenic rice plants that...

Experimental investigation of quantum entropic uncertainty relations for multiple measurements in pure diamond

One unique feature of quantum mechanics is the Heisenberg uncertainty principle, which states that the outcomes of two incompatible measurements cannot simultaneously achieve arbitrary precision. In an information-theoretic context of quantum information, the uncertainty principle can be formulated as entropic uncertainty relations with two measurements for a quantum bit (qubit...

Comparison of impulsivity in non-problem, at-risk and problem gamblers

As a non-substance addiction, gambling disorder represents the model for studying the neurobiology of addiction without toxic consequences of chronic drug use. From a neuropsychological perspective, impulsivity is deemed as a potential construct responsible in the onset and development of drug addiction. The objective of this study was to investigate the associations between...