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Search: authors:"Rishi Pruthi"

4 papers found.
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Patient attitudes towards kidney transplant listing: qualitative findings from the ATTOM study

Background There is variation in time to listing and rates of listing for transplantation between renal units in the UK. While research has mainly focused on healthcare organization, little is known about patient perspectives of entry onto the transplant waiting list. This qualitative study aimed to explore patients' views and experiences of kidney transplant listing.

Transplantation clinical

Introduction and Aims: An unusual population of pro-inflammatory CD4+ T cells that have lost the co-stimulatory molecule CD28 (CD4+CD28null T cells) is expanded in patients with end-stage renal disease (ESRD). CD4+CD28null T cells are associated with cardiovascular disease and may cause atherosclerotic plaque instability by their highly pro-inflammatory nature. In this study we...

Paediatric nephrology II

Introduction and Aims: Renal interstitial fibrosis is a final common pathway in chronic kidney disease (CKD) progression, independent of its origin. Matrix metalloproteinases (MMPs) are known for their proteolytic activity, regulating extracellular matrix content and tissue remodeling. The increased serum levels of MMPs have been described both in children and adults with...

Transplantation: clinical studies - A

Introduction and Aims: Endothelial dysfunction can be detected at early stages of chronic kidney disease (CKD). Although endothelial functions improve after successful renal transplantation, renal transplant recipients have still worse endothelial functions compared to healthy subjects. Recent trials showed that vitamin D deficiency and high fibroblast growth factor-23 (FGF-23...