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Epicardial and visceral adipose tissue in relation to subclinical atherosclerosis in a Chinese population

traditional cardiovascular risk factors particularly dyslipidemia and hyperglycemia. Author Contributions Conceptualization: Tai E. Shyong, Jeannette Lee, Alvin Ng, Rob M. Van Dam. Data curation: Nang Ei Ei ... Ei Ei Khaing, Tai E. Shyong, Jeannette Lee, Alvin Ng, Rob M. Van Dam. Resources: Tai E. Shyong, Jeannette Lee, Alvin Ng. Software: Nang Ei Ei Khaing, Cinnie Yentia Soekojo. Supervision: Tai E. Shyong

Dietary intake and diabetic retinopathy: A systematic review

Investigation: Mark Y. Z. Wong, Ryan E. K. Man, Eva K. Fenwick, Ecosse L. Lamoureux. Methodology: Mark Y. Z. Wong, Ryan E. K. Man, Eva K. Fenwick, Preeti Gupta, Ling-Jun Li, Rob M. van Dam, Mary F. Chong, Ecosse ... , Ling-Jun Li, Rob M. van Dam, Mary F. Chong, Ecosse L. Lamoureux. 22 / 26 23 / 26 Alcubierre N, Valls J, Rubinat E, Cao G, Esquerda A, Traveset A, et al. Vitamin D Deficiency Is Associated with the

Gene-diet interaction effects on BMI levels in the Singapore Chinese population

Recent genome-wide association studies (GWAS) have identified 97 body-mass index (BMI) associated loci. We aimed to evaluate if dietary intake modifies BMI associations at these loci in the Singapore Chinese population. We utilized GWAS information from six data subsets from two adult Chinese population (N = 7817). Seventy-eight genotyped or imputed index BMI single nucleotide...

Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose–response meta-analysis

Background Considerable controversy exists regarding the relation between maternal caffeine intake during pregnancy and risk of low birth weight (birth weight <2,500 g). We aim to assess this association using a systematic review and dose–response meta-analysis of prospective studies. Methods Potential articles were identified by searching MEDLINE and SCOPUS databases through 17...

Effect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials

. The second screening of those full text articles was then independently performed by at least two reviewers (Nithya Neelakantan, Madanagopal Narayanan, Rob M van Dam). Disagreements were resolved by ... standardized data extraction form. Differences in data extraction were resolved by a third reviewer (Rob M van Dam). The quality assessment was conducted using the CONSORT statement for herbal trials [31] by two

Overweight in Early Adulthood, Adult Weight Change, and Risk of Type 2 Diabetes, Cardiovascular Diseases, and Certain Cancers in Men: a Cohort Study

Mutsert, Qi Sun, Walter C. Willett, Frank B. Hu, Rob M. van Dam); Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston ... Health and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore (Rob M. van Dam). This work was supported by the

Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women

Aims/hypothesis Coffee and tea consumption has been associated with a lower type 2 diabetes risk but little is known about how changes in coffee and tea consumption influence subsequent type 2 diabetes risk. We examined the associations between 4 year changes in coffee and tea consumption and risk of type 2 diabetes in the subsequent 4 years. Methods We prospectively followed 48...

Association of Television Viewing Time with Body Composition and Calcified Subclinical Atherosclerosis in Singapore Chinese

Objective Sedentary behavior such as television viewing may be an independent risk factor for coronary heart disease. However, few studies have assessed the impact of television viewing time on coronary artery calcification and it remains unclear how body fat contributes to this relationship. The aim of this study is to evaluate the association between television viewing time and...

Television screen time, but not computer use and reading time, is associated with cardio-metabolic biomarkers in a multiethnic Asian population: a cross-sectional study

Background Recent evidence shows that sedentary behaviour may be an independent risk factor for cardiovascular diseases, diabetes, cancers and all-cause mortality. However, results are not consistent and different types of sedentary behaviour might have different effects on health. Thus the aim of this study was to evaluate the association between television screen time, computer...

Gut Microbiota Metabolites of Dietary Lignans and Risk of Type 2 Diabetes: A Prospective Investigation in Two Cohorts of U.S. Women. Diabetes Care 2014;37:1287–1295

Qi Sun Nicole M. Wedick An Pan Mary K. Townsend Aedin Cassidy Adrian A. Franke Eric B. Rimm Frank B. Hu Rob M. van Dam

Evidence of a Causal Relationship Between Adiponectin Levels and Insulin Sensitivity: A Mendelian Randomization Study

He Gao Tove Fall Rob M. van Dam Allan Flyvbjerg Bjrn Zethelius Erik Ingelsson Sara Hgg The adipocyte-secreted protein adiponectin is associated with insulin sensitivity in observational studies. We

Gut Microbiota Metabolites of Dietary Lignans and Risk of Type 2 Diabetes: A Prospective Investigation in Two Cohorts of U.S. Women

OBJECTIVE To examine urinary levels of enterolactone and enterodiol, intestinal microbial metabolites of dietary lignans, in relation to type 2 diabetes (T2D) risk.

A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population

Polyunsaturated fatty acids (PUFAs) have a major impact on human health. Recent genome-wide association studies (GWAS) have identified several genetic loci that are associated with plasma levels of n-3 and n-6 PUFAs in primarily subjects of European ancestry. However, the relevance of these findings has not been evaluated extensively in other ethnic groups. The primary aim of...

Physical Activity Before and During Pregnancy and Risk of Gestational Diabetes Mellitus: A meta-analysis

A meta-analysis DEIRDRE K. TOBIAS SM CUILIN ZHANG PHD ROB M. VAN DAM PHD KATHERINE BOWERS PHD FRANK B. HU PHD R e v i e w s / C o m m e n t a r i e s / A D A OBJECTIVE - Gestational diabetes

Dietary Patterns During Adolescence and Risk of Type 2 Diabetes in Middle-Aged Women

VASANTI S. MALIK SCD TERESA T. FUNG SCD ROB M. VAN DAM PHD ERIC B. RIMM SCD BERNARD ROSNER PHD FRANK B. HU PHD OBJECTIVEdWhether dietary habits early in life can affect risk of type 2 diabetes

Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial

Background Coffee consumption has been associated with a lower risk of type 2 diabetes in prospective cohort studies, but the underlying mechanisms remain unclear. The aim of this study was to evaluate the effects of regular and decaffeinated coffee on biological risk factors for type 2 diabetes. Methods Randomized parallel-arm intervention conducted in 45 healthy overweight...

Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial

author, Aoife M Brennan2, Qi Sun1, 4, Frank B Hu1, 3, 4, Christos S Mantzoros†2, 5, 6 and Rob M van Dam†1, 3, 4 †Contributed equally Nutrition Journal201110:93 https://doi.org/10.1186/1475-2891-10 ... widespread consumption of coffee, the effects of coffee and coffee components on metabolic risk factors warrant further investigation. Notes Christos S Mantzoros and Rob M van Dam contributed equally to

The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial

Background Findings from observational studies suggest that sex hormone-binding globulin (SHBG) and endogenous sex hormones may be mediators of the putative relation between coffee consumption and lower risk of type 2 diabetes. The objective of this study was to evaluate the effects of caffeinated and decaffeinated coffee on SHBG and sex hormone levels. Findings After a two-week...

Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

Coffee consumption is associated with a lower risk of type 2 diabetes. We tested the hypothesis that this is mediated by incretin hormones by measuring the acute effects of decaffeinated coffee and coffee components on GLP-1 and GIP concentrations. A randomized cross-over trial of the effects of 12 g decaffeinated coffee, 1 g chlorogenic acid, 500 mg trigonelline, and placebo on...

Comparison of Dual-Energy X-Ray Absorptiometric and Anthropometric Measures of Adiposity in Relation to Adiposity-Related Biologic Factors

, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts (Qi Sun, Rob M. van Dam, Donna Spiegelman, Walter C. Willett, Frank B. Hu); Department of Nutrition, Harvard School of Public ... Health, Boston, Massachusetts (Rob M. van Dam, Walter C. Willett, Frank B. Hu); Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts (Rob M. van Dam, Donna Spiegelman, Walter