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Search: authors:"Rodrigo R. Catharino"

7 papers found.
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Thermal degradation of sucralose: a combination of analytical methods to determine stability and chlorinated byproducts

. Catharino 0 0 INNOVARE Biomarkers Laboratory, School of Pharmaceutical Sciences, University of Campinas , Campinas, Sa?o Paulo, Brazil, 13083-877 unicamp.br) In the late years, much attention has been

Rapid and Simultaneous In Situ Assessment of Aflatoxins and Stilbenes Using Silica Plate Imprinting Mass Spectrometry Imaging

A fast and direct combination of techniques for simultaneous mycotoxin and phytoalexin identification in peanut skin and kernel is described. Silica Plate Imprinting Laser Desorption/Ionization Mass Spectrometry Imaging (SPILDI-MSI) is a powerful technique that exhibits great advantages, such as solvent-free and matrix-free characteristics, as well as no sample preparation or...

Correlation between Mitochondrial Reactive Oxygen and Severity of Atherosclerosis

Atherosclerosis has been associated with mitochondria dysfunction and damage. Our group demonstrated previously that hypercholesterolemic mice present increased mitochondrial reactive oxygen (mtROS) generation in several tissues and low NADPH/NADP

Fatty Acid Synthase Inhibitors Induce Apoptosis in Non-Tumorigenic Melan-A Cells Associated with Inhibition of Mitochondrial Respiration

The metabolic enzyme fatty acid synthase (FASN) is responsible for the endogenous synthesis of palmitate, a saturated long-chain fatty acid. In contrast to most normal tissues, a variety of human cancers overexpress FASN. One such cancer is cutaneous melanoma, in which the level of FASN expression is associated with tumor invasion and poor prognosis. We previously reported that...

Blends of soybean biodiesel with petrodiesel: direct quantitation via mass spectrometry

Quantitation and identification of blends of soybean biodiesel with petrodiesel were performed via mass spectrometry using two ionization techniques: electrospray ionization (ESI) and Venturi easy ambient sonic-spray ionization in its liquid mode (VL-EASI). Different soybean biodiesel/petrodiesel blends (from B0 to B100) were diluted and then directly infused and analyzed by both...

Irradiated Riboflavin Diminishes the Aggressiveness of Melanoma In Vitro and In Vivo

Melanoma is one of the most aggressive skin cancers due to its high capacity to metastasize. Treatment of metastatic melanomas is challenging for clinicians, as most therapeutic agents have failed to demonstrate improved survival. Thus, new candidates with antimetastatic activity are much needed. Riboavin (RF) is a component of the vitamin B complex and a potent photosensitizer...

Mass spectrometry analysis of surface tension reducing substances produced by a pah-degrading Pseudomonas citronellolis strain

In this work we investigated the structure of the iron-stimulated surface tension reducing substances produced by P. citronellolis 222A isolated from a 17-years old landfarming used for sludge treatment in petrochemical industries and oil refinery. Its mass spectrum differs from P. aeruginosa spectrum, indicating that the surface tension reducing substances produced by P...