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Search: authors:"Romain Sonneville"

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Brainstem response patterns in deeply-sedated critically-ill patients predict 28-day mortality

, CleÂmence Marois, AureÂlien Mazeraud, Nicolas Mongardon, ReÂgine Morizot-Koutlidis, Lionel Naccache, Vincent Navarro, Herve Outin, Andrea Polito, Benjamin Rohaut, Shidasp Siami, Romain Sonneville, Pierre

Changes in CRH and ACTH Synthesis during Experimental and Human Septic Shock

Context The mechanisms of septic shock-associated adrenal insufficiency remain unclear. This study aimed at investigating the synthesis of corticotropin-releasing hormone (CRH) and vasopressin (AVP) by parvocellular neurons and the antehypophyseal expression of ACTH in human septic shock and in an experimental model of sepsis. Objective To test the hypothesis that ACTH secretion...