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Dopamine receptor antagonists as potential therapeutic agents for ADPKD

comments on the manuscript and Avi Z. Rosenberg (Johns Hopkins) for helpful discussion. Author Contributions Conceptualization: Rong Li. Formal analysis: Jay R. Unruh. Funding acquisition: Rong Li ... . Investigation: Parama Paul, Sreekumar Ramachandran. Methodology: Sheng Xia, Juliana Conkright-Fincham. Project administration: Parama Paul, Rong Li. Resources: Sheng Xia. Supervision: Rong Li. Validation

Application of Bacillus velezensis NJAU-Z9 Enhanced Plant Growth Associated with Efficient Rhizospheric Colonization Monitored by qPCR with Primers Designed from the Whole Genome Sequence

), the China Scholarship Council (award to Rong Li for 1 year’s abroad study), and Top-notch Academic Programs Project of Jiangsu Higher Education Institution (PPZY2015A061). Compliance with Ethical

Porphyromonas gingivalis-Induced MIF Regulates Intercellular Adhesion Molecule-1 Expression in EA.hy926 Cells and Monocyte-Endothelial Cell Adhesion Through the Receptors CD74 and CXCR4

Abstract Porphyromonas gingivalis (P. gingivalis) is an important pathogen that contributes to periodontal disease and causes infections that promote the progression of atherosclerosis. Our previous studies showed that macrophage migration inhibitory factor (MIF) facilitates monocyte adhesion to endothelial cells by regulating the expression of intercellular adhesion molecule-1...

New insights into the genic and metabolic characteristics of induced pluripotent stem cells from polycystic ovary syndrome women

BackgroundPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that affects female fertility. However, with the lack of a corresponding research model, the pathology mechanism of PCOS is poorly understood. Induced pluripotent stem cell (iPSC) technology has been recognized as means to generate patient-specific stem cells for disease modeling.MethodsThe...

Applications of Parameterized Nonlinear Ordinary Differential Equations and Dynamic Systems: An Example of the Taiwan Stock Index

2018; Published 12 April 2018 Academic Editor: Tongxing Li Copyright © 2018 Meng-Rong Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Applications of Parameterized Nonlinear Ordinary Differential Equations and Dynamic Systems: An Example of the Taiwan Stock Index

2018; Published 12 April 2018 Academic Editor: Tongxing Li Copyright © 2018 Meng-Rong Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity

Rong Li,1 Wen Xing,1 Feng-Chun Yang,2,3 Jie Bai,1,4 and Yuan Zhou1 1State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Center for Stem Cell Medicine ... interests. Authors’ Contributions Hui Shi, Yingshao Wang, and Rong Li contribute equally to this work. Acknowledgments This work was supported in part by grants from the National Natural Science Foundation of

Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity

Rong Li,1 Wen Xing,1 Feng-Chun Yang,2,3 Jie Bai,1,4 and Yuan Zhou1 1State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Center for Stem Cell Medicine ... interests. Authors’ Contributions Hui Shi, Yingshao Wang, and Rong Li contribute equally to this work. Acknowledgments This work was supported in part by grants from the National Natural Science Foundation of

Adaptive Constrained Control for Uncertain Nonlinear Time-Delay System with Application to Unmanned Helicopter

This paper investigates a class of nonlinear time-delayed systems with output prescribed performance constraint. The neural network and DOB (disturbance observer) are designed to tackle the uncertainties and external disturbance, and prescribed performance function is constructed for the output prescribed performance constrained problem. Then the robust controller is designed by...

Identification of key design characteristics for complex product adaptive design

Key design characteristics (KDCs) are important information related to the product and part designs, which significantly influence on the product’s functions, performances, and quality. Identifying KDCs for a complex product will help designers to focus on key design parameters during the design process and rapidly obtain design schemes based on their close relationships to the...

GATA-4-expressing mouse bone marrow mesenchymal stem cells improve cardiac function after myocardial infarction via secreted exosomes

-Gang He, Hong-Rong Li, Dan Yan and Jin-Xiu Han acquired the data. Ji-Gang He, Hong-Rong Li and Jin-Xiu Han analyzed the data. JiGang He, Jin-Xiu Han and Bei-Bei Li showed statistical analysis. Ji-Gang He

Comprehensive damage evaluation of localized spallation of thermal barrier coatings

Thermal barrier coatings (TBCs) enable the hot section part to work at high temperatures owing to their thermal barrier effect on the base metal components. However, localized spallation in the ceramic top-coat might occur after long duration of thermal exposure or thermal cycling. To comprehensively understand the damage of the top-coat on the overall hot section part, effects...

Temperature-dependent cell death patterns induced by functionalized gold nanoparticle photothermal therapy in melanoma cells

Academy of Medical Sciences, Nanchang, ChinaYujuan Zhang, Xuelin Zhan, Shanshan Peng, Wei Huang, Ying Cai, Yanling Liu, Rong Li, Keng Yuan, Nanjin Zhou & Weiping MinJiangxi Provincial Key Laboratory of ... • PubMed • Google Scholar Search for Yanling Liu in:Nature Research journals • PubMed • Google Scholar Search for Rong Li in:Nature Research journals • PubMed • Google Scholar Search for Keng Yuan

Continuous application of different organic additives can suppress tomato disease by inducing the healthy rhizospheric microbiota through alterations to the bulk soil microflora

AimsBio-organic fertilizer and different additives are widely applied to suppress soil-borne diseases. However, how different additives alter bulk soil microflora and thereby induce the healthy rhizospheric microflora remains unclear.MethodsA 3-season field experiment containing four fertilization management programs (chemical fertilizer, organic fertilizer, amino acid organic...

Premna grandipaniculata (Lamiaceae, Premnoideae), a remarkable new species from north Myanmar

A remarkable new Premna species from Myanmar, P. grandipaniculata Y.H.Tan & Bo Li (Lamiaceae), is here described and illustrated. It differs from all known congeneric taxa by having huge complicated panicles which have tertiary branches formed by spike-like thyrses. In Premna, such a spike-like thyrse is found in P. bracteata and P. interrupta, but those species can be easily...

Continuous-wave Y-band planar BWO with wide tunable bandwidth

A high performance continuous-wave (CW) backward wave oscillator (BWO) with planar slow wave structure (SWS) and sheet electron beam in Y-band is presented in this paper. The mode selection is discussed by studying the dispersion curve of SWSs, distributions of the electric field, and particle-in-cell simulation results, showing that the designed BWO operates in the fundamental...

The distinct roles of mesenchymal stem cells in the initial and progressive stage of hepatocarcinoma

Increasing evidences suggest that mesenchymal stem cells (MSCs) could migrate to the tumor site and play a vital role in tumorigenesis and progression. However, it is still a lively debate whether MSCs exert a pro- or anticancer action. Cancer development and progression is a multistep process. Therefore, we investigated the effect of MSCs on hepatocarcinoma and whether the role...

Calycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling

Clinically, breast cancer is generally classified into estrogen receptor-positive (ER+) or estrogen receptor-negative (ER−) subtypes. The phytoestrogen calycosin has been shown to inhibit the proliferation of ER+ cells, which may be mediated by a feedback loop that involves miR-375, RAS dexamethasone-induced 1 (RASD1), and ERα. However, how calycosin acts on ER− breast cancer...

DNA methylation reprogramming of functional elements during mammalian embryonic development

Reproductive Endocrinology and Assisted Reproductive Technology, Center of Reproductive Medicine, Peking University Third Hospital, 100191, Beijing, ChinaCongru Li, Rong Li, Jie Yan, Ying Lian, Ping Liu, Yue ... • PubMed • Google Scholar Search for Xiaocui Xu in:Nature Research journals • PubMed • Google Scholar Search for Jialei Duan in:Nature Research journals • PubMed • Google Scholar Search for Rong Li