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Association of trans fatty acids with lipids and other cardiovascular risk factors in an Indian industrial population

Trans-fat, an invariable component of industrial fat is considered as one of the major dietary factors associated with CVD. Although the use of trans-fat is completely banned in some of the high-income countries where the CVD epidemic is declining, it is widely used in LMIC. We aimed to investigate the association of trans fatty acid in serum with risk markers of CVD in an...

Comparison of multiple obesity indices for cardiovascular disease risk classification in South Asian adults: The CARRS Study

Background We comparatively assessed the performance of six simple obesity indices to identify adults with cardiovascular disease (CVD) risk factors in a diverse and contemporary South Asian population. Methods 8,892 participants aged 20–60 years in 2010–2011 were analyzed. Six obesity indices were examined: body mass index (BMI), waist circumference (WC), waist-height ratio...

Intra-household evaluations of alcohol abuse in men with depression and suicide in women: A cross-sectional community-based study in Chennai, India

Background Harmful effects of alcohol abuse are well documented for drinkers, and adverse effects are also reported for the physical and emotional well-being of family members, with evidence often originating from either drinkers or their families in clinic-based settings. This study evaluates intra-household associations between alcohol abuse in men, and depression and suicidal...

Prevalence of chronic kidney disease and risk factors for its progression: A cross-sectional comparison of Indians living in Indian versus U.S. cities

Background While data from the latter part of the twentieth century consistently showed that immigrants to high-income countries faced higher cardio-metabolic risk than their counterparts in low- and middle-income countries, urbanization and associated lifestyle changes may be changing these patterns, even for conditions considered to be advanced manifestations of cardio...

Is vulnerability to cardiometabolic disease in Indians mediated by abdominal adiposity or higher body adiposity

-Shlomo Ruby Gupta Bharati Kulkarni Dorairaj Prabhakaran George Davey Smith Jonathan Wells Shah Ebrahim Sanjay Kinra 0 Clinical Research Department, London School of Hygiene & Tropical Medicine , Keppel

Socio-economic patterning of cardiometabolic risk factors in rural and peri-urban India: Andhra Pradesh children and parents study (APCAPS)

AimTo assess the prevalence of cardiometabolic risk factors by socio-economic position (SEP) in rural and peri-urban Indian population.Subjects and methodsCross-sectional survey of 3,948 adults (1,154 households) from Telangana (2010–2012) was conducted to collect questionnaire-based data, physical measurements and fasting blood samples. We compared the prevalence of risk factors...

A rapid 3% polyacrylamide slab gel electrophoresis method for high through put screening of LDL phenotype

Background Small dense LDL is reported to be associated with increased coronary artery disease risk by various epidemiological studies. The gold standard for separation and identification of LDL subtypes in plasma is ultracentrifugation which is a lengthy procedure and difficult to perform. Various other methods like NMR, HPLC, gradient gel electrophoresis (GGE) have been...

Use of dried blood for measurement of trans fatty acids

Background Fatty acid measurements especially trans fatty acid has gained interest in recent times. Among the various available biomarkers, adipose tissue is considered to be the best for the long term dietary intake but the invasive nature of tissue aspiration reduces its utility. Phlebotomy is a much less invasive method of sample collection when a large number of participants...

Association of high sensitive C-reactive protein (hsCRP) with established cardiovascular risk factors in the Indian population

Lakhmy Ramakrishnan Ruby Gupta F Ahmed KR Thankappan CC Kartha Vivek Chaturvedi KS Reddy for the Sentinel Surveillance in Industrial Populations Study Group 0 Centre for Chronic Disease Control , New Delhi