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Optimal pharmacological therapy in ST-elevation myocardial infarction—a review

in catheterisation laboratory after angiography) and the means of administration (intravenous, intracoronary administration). Conflict of interest R.S. Hermanides, S. Kilic and A.W.J. van’t Hof

Effects of radial versus femoral artery access in patients with acute myocardial infarction: A large centre prospective registry

differences in baseline characteristics. Acknowledgements We thank Vera Derks for her excellent editorial assistance. Funding None. Conflict of interest S. Kilic, R.S. Hermanides, J.P. Ottervanger, E

Initial Experience with Robotic Retropubic Urethropexy Compared to Open Retropubic Urethropexy

. Kilic Department of Obstetrics and Gynecology, The University of Texas Medical Branch in Galveston, 301 University Boulevard, Galveston, TX 77555-0587, USA Received 13 June 2013; Accepted 10 August 2013

Human CD3γ, but not CD3δ, haploinsufficiency differentially impairs γδ versus αβ surface TCR expression

Background The T cell antigen receptors (TCR) of αβ and γδ T lymphocytes are believed to assemble in a similar fashion in humans. Firstly, αβ or γδ TCR chains incorporate a CD3δε dimer, then a CD3γε dimer and finally a ζζ homodimer, resulting in TCR complexes with the same CD3 dimer stoichiometry. Partial reduction in the expression of the highly homologous CD3γ and CD3δ proteins...

Catechol-O-Methyltransferase Expression and 2-Methoxyestradiol Affect Microtubule Dynamics and Modify Steroid Receptor Signaling in Leiomyoma Cells

Context Development of optimal medicinal treatments of uterine leiomyomas represents a significant challenge. 2-Methoxyestradiol (2ME) is an endogenous estrogen metabolite formed by sequential action of CYP450s and catechol-O-methyltransferase (COMT). Our previous study demonstrated that 2ME is a potent antiproliferative, proapoptotic, antiangiogenic, and collagen synthesis...


Introduction: Degradation of basement membrane (BM) is reported to be involved in the metastatic process of cancers. BM components, collagen four (COLIV) and laminin, have also been shown to be aberrantly expressed in the benign metastatic disease of endometriosis. Cytokeratin 5/6 (Ck5/6) and podocalyxin-like protein (PODXL) have been proposed as markers of stem cells. We aim to...