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19 papers found.
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Addition of nonalbumin proteinuria to albuminuria improves prediction of type 2 diabetic nephropathy progression

Albuminuria is generally accepted as a sensitive marker of diabetic nephropathy but has limitations in predicting its progression. The aim of this study was to evaluate the use of nonalbumin proteinuria in addition to albuminuria for predicting the progression of type 2 diabetic nephropathy. In this retrospective observational study, the urine albumin-to-creatinine ratio (ACR...

Evaluation of protective efficacy induced by virus-like particles containing a Trichinella spiralis excretory-secretory (ES) protein in mice

Background The frequent outbreaks of human trichinellosis globally underscore the need to develop effective vaccine. We hypothesized that a novel vaccine could improve vaccine efficacy against Trichinella spiralis. Methods In this study, we developed virus-like particles (VLPs) containing the 53 KDa excretory/secretory (ES) protein of T. spiralis and the influenza matrix protein...

Visualization of a Mammalian Mitochondrion by Coherent X-ray Diffractive Imaging

• Google Scholar Search for Daewoong Nam in:Nature Research journals • PubMed • Google Scholar Search for Sang Soo Kim in:Nature Research journals • PubMed • Google Scholar Search for Jae Hyun Park

Arterial Stiffness Is More Associated with Albuminuria than Decreased Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus: The REBOUND Study

Internal Medicine, College of Medicine, Pusan Paik Hospital, Inje University, Busan, Republic of Korea Correspondence should be addressed to Sang Soo Kim; moc.liamg@7mikssrd and In Joo Kim; rk.ca.nasup ... wrote and edited the manuscript. Sang Soo Kim and In Joo Kim researched the data, contributed to the discussion, and reviewed the manuscript. Bo Hyun Kim, Ja Young Park, Chang Won Lee, Ji Hye Suk, Sun Hae

Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy

Background We recently reported on the enhanced expression of two isoforms of matrix metalloproteinase-2 (MMP-2) in human renal transplantation delayed graft function. These consist of the conventional secreted, full length MMP-2 isoform (FL-MMP-2) and a novel intracellular N-Terminal Truncated isoform (NTT-MMP-2) generated by oxidative stress-mediated activation of an alternate...

Dynamic manipulation of particles via transformative optofluidic waveguides

Ha, Jin Ho Jung, Hyung Jin Sung & Sang Soo Kim AuthorsSearch for Kang Soo Lee in:Nature Research journals • PubMed • Google ScholarSearch for Kyung Heon Lee in:Nature Research journals • PubMed ... Research journals • PubMed • Google ScholarSearch for Hyung Jin Sung in:Nature Research journals • PubMed • Google ScholarSearch for Sang Soo Kim in:Nature Research journals • PubMed • Google Scholar

High metabolic tumor volume and total lesion glycolysis are associated with lateral lymph node metastasis in patients with incidentally detected thyroid carcinoma

Kim Keunyoung Kim Heeyoung Kim So Jung Kim Won Jin Kim Yun Kyung Jeon Sang Soo Kim Yong Ki Kim In Joo Kim Yong Ki Kim Objective The objective of this study was to investigate whether total lesion

Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer

Background In thyroid cancer, preoperative ultrasonography (US) is performed to detect the primary tumor and lymph node metastasis (LNM), which are related to prognosis. This study examined the relationships between specific US findings and LNM in micropapillary thyroid cancer (MPTC). Methods Data on 220 patients with solitary MPTC who underwent total thyroidectomy and neck...

Inhibition of Androgen Receptor Expression with Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells

14 December 2012; Accepted 10 January 2013 Academic Editors: T. Esen and A. Tefekli Copyright © 2013 Sang Soo Kim et al. This is an open access article distributed under the Creative Commons

Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation

Soo Kim in:Nature Research journals • PubMed • Google ScholarSearch for Kirti Shetty in:Nature Research journals • PubMed • Google ScholarSearch for Bibhuti Mishra in:Nature Research journals • PubMed ... journals • PubMed • Google ScholarSearch for Alexandros Tzatsos in:Nature Research journals • PubMed • Google ScholarSearch for Shulin Li in:Nature Research journals • PubMed • Google ScholarSearch for Sang

Dual Silencing of Hsp27 and c-FLIP Enhances Doxazosin-Induced Apoptosis in PC-3 Prostate Cancer Cells

Sang Soo Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction in any medium, provided the

Soluble α-Klotho as a Novel Biomarker in the Early Stage of Nephropathy in Patients with Type 2 Diabetes

Objective Although α-klotho is known as an anti-aging, antioxidant, and cardio-renal protective protein, the clinical implications of soluble α-klotho levels in patients with diabetes have not been evaluated. Therefore, this study evaluated whether plasma and urinary α-klotho levels are associated with albuminuria in kidney disease in diabetes. Research Design and Methods A total...

Urinary Cystatin C and Tubular Proteinuria Predict Progression of Diabetic Nephropathy

SANG SOO KIM SANG HEON SONG PHD IN JOO KIM PHD YUN KYUNG JEON BO HYUN KIM PHD IHM SOO KWAK PHD EUN KYUNG LEE RPH YONG KI KIM PHD OBJECTIVEdThe aim of this study was to evaluate the association of

A prospective observational study with dose volume parameters predicting rectosigmoidoscopic findings and late rectosigmoid bleeding in patients with uterine cervical cancer treated by definitive radiotherapy

Purpose We assessed the value of dose-volumetric parameters predicting rectosigmoid mucosal changes (RMC) and late rectosigmoid complications (LRC). Methods Between January 2004 and February 2006, 77 patients with stage IB-IIIB cervical cancer underwent external beam radiotherapy and computed tomography (CT)-based intracavitary irradiation. Total dose to the rectal point and...

Radiobiological Characterization of Proton Beam at the National Cancer Center in Korea

Hye-Jung BAEK Tae-Hyun KIM Dongho SHIN Jung-Won KWAK Dong-Wan CHOO Se-Byung LEE Yoshiya FURUSAWA Koichi ANDO Sang-Soo KIM Kwan-Ho CHO Proton beam therapy/RBE/Colonogenic assay/MTT assay. Estimation

Tissue engineering of heart valves by recellularization of glutaraldehyde-fixed porcine valves using bone marrow-derived cells

To increase the biocompatibility and durability of glutaraldehyde (GA)-fixed valves, a biological coating with viable endothelial cells (ECs) has been proposed. However, stable EC layers have not been formed successfully on GA-fixed valves due to their inability to repopulate. In this study, to improve cellular adhesion and proliferation, the GA-fixed prostheses were detoxified...

Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma

The aim of this study was to identify molecular markers associated with oncogenic differentiation in hepatocellular carcinoma (HCC). Using an unsupervised clustering method with a cDNA microarray, HCC (T) gene expression profiles and corresponding non-tumor tissues (NT) from 40 patients were analyzed. Of total 217 genes, 72 were expressed preferentially in HCC tissues. Among 186...