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The effect of positive changes during intraoperative monitoring of the functional improvement in patients with cervical compressive myelopathy

The effect of positive changes during intraoperative monitoring of the functional improvement in patients with cervical compressive myelopathy Min Kyu Park,1 Sook Joung Lee,2 Sang Beom Kim,3 Kyeong ... Medicine, Dong-A University , Busan, republic of Korea from roF PowerdbyTCPDF(ww.tcpdf.org) sook Joung lee 2 sang Beom Kim 3 Kyeong Woo lee 3 hye-Jeong lee 4 eun Young han 5 Bo ryun Kim 5 Background

Computational investigation of dynamical transitions in Trp-cage miniprotein powders

We investigate computationally the dynamical transitions in Trp-cage miniprotein powders, at three levels of hydration: 0.04, 0.26 and 0.4 g water/g protein. We identify two distinct temperatures where transitions in protein dynamics occur. Thermal motions are harmonic and independent of hydration level below Tlow ≈ 160 K, above which all powders exhibit harmonic behavior but...

Effect of Donor Age on the Proportion of Mesenchymal Stem Cells Derived from Anterior Cruciate Ligaments

The characteristics of anterior cruciate ligament (ACL)-derived mesenchymal stem cells (MSCs), such as proportion and multilineage potential, can be affected by donor age. However, the qualitative and quantitative features of ACL MSCs isolated from younger and older individuals have not yet been compared directly. This study assessed the phenotypic and functional differences in...

A novel homozygous MPV17 mutation in two families with axonal sensorimotor polyneuropathy

Background Mutations in MPV17 cause the autosomal recessive disorder mitochondrial DNA depletion syndrome 6 (MTDPS6), also called Navajo neurohepatopathy (NNH). Clinical features of MTDPS6 is infantile onset of progressive liver failure with seldom development of progressive neurologic involvement. Methods Whole exome sequencing (WES) was performed to isolate the causative gene...

Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation

Distal hereditary motor neuropathy (dHMN) is a heterogeneous disorder characterized by degeneration of motor nerves in the absence of sensory abnormalities. Recently, mutations in the small heat shock protein 27 (HSP27) gene were found to cause dHMN type II or Charcot-Marie-Tooth disease type 2F (CMT2F). The authors studied 151 Korean axonal CMT or dHMN families, and found a...