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Search: authors:"Sara Zagaglia"

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Cerebrospinal fluid lactate is associated with multiple sclerosis disease progression

Background Altered cerebrospinal fluid (CSF) levels of lactate have been described in neurodegenerative diseases and related to mitochondrial dysfunction and neuronal degeneration. We investigated the relationship between CSF lactate levels, disease severity, and biomarkers associated with neuroaxonal damage in patients with multiple sclerosis (MS). Methods One-hundred eighteen...