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Search: authors:"Satoshi Akagi"

3 papers found.
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Crucial role of RAGE in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension

Matsubara. 9 / 11 Data curation: Kazufumi Nakamura, Masakiyo Sakaguchi, Satoshi Akagi, Toshihiro Sarashina, Kentaro Ejiri, Kaoru Akazawa, Megumi Kondo, Koji Nakagawa, Takeshi Ogo, Takahiro Oto, Shinichi ... Toyooka, Yuichiro Higashimoto, Kei Fukami. Formal analysis: Kazufumi Nakamura, Satoshi Akagi. Funding acquisition: Kazufumi Nakamura, Hiroshi Ito. Investigation: Kazufumi Nakamura, Satoshi Akagi, Koji

Comparison of DNA methylation levels of repetitive loci during bovine development

Background DNA methylation of cytosine residues in CpG dinucleotide controls gene expression and dramatically changes during development. Its pattern is disrupted in cloned animals suggesting incomplete reprogramming during somatic cell nuclear transfer (the first reprogramming). However, the second reprogramming occurs in the germ cells and epigenetic errors in somatic cells of...

Circulating KCNH2 Current-Activating Factor in Patients with Heart Failure and Ventricular Tachyarrhythmia

Background It is estimated that approximately half of the deaths in patients with HF are sudden and that the most likely causes of sudden death are lethal ventricular tachyarrhythmias such as ventricular tachycardia (VT) or fibrillation (VF). However, the precise mechanism of ventricular tachyarrhythmias remains unknown. The KCNH2 channel conducting the delayed rectifier K...