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Renewal of the Major Fields

, Ferdinand Peper, and Satoshi Murata. Ichise succeeds Nishida and continues to handle the major field ''Cognitive Computing'' though the topics of the field slightly change due to the expertise of Ichise ... systems: investigating emergence of order in artificial and natural systems based on chemical/physical/biological interactions Area Editor Satoshi Murata Tohoku University The last renewal of the major

Acceleration of small bowel motility after oral administration of dai-kenchu-to (TJ-100) assessed by cine magnetic resonance imaging

, Hiroshi Yamamoto. 9 / 11 Data curation: Akitoshi Inoue, Shinichi Ohta, Sachiko Kaida, Tsuyoshi Yamaguchi, Satoshi Murata, Toru Obata. Formal analysis: Akitoshi Inoue, Akira Furukawa, Shinichi Ohta, Nguyen

Prognostic impact of CD44-positive cancer stem-like cells at the invasive front of gastric cancer

Background:The invasive tumour front may provide prognostic information. We examined the relationship between the presence of cancer stem cells (CSCs) at the invasive tumour front and prognosis in gastric cancer (GC).Methods:CD44 is a CSC marker; accordingly, CD44 standard (CD44s), CD44 variant-6 (CD44v6), and CD44 variant-9 (CD44v9) expression were examined in 123 resected...

Stratified phase II trial to establish the usefulness of the collagen gel droplet embedded culture-drug sensitivity test (CD-DST) for advanced gastric cancer

Background We conducted a multicenter phase II trial to assess the suitability of three types of chemotherapy (docetaxel plus S-1, irinotecan plus S-1, or S-1 alone) for patients with advanced gastric cancer by means of the collagen gel droplet embedded culture-drug sensitivity test (CD-DST). To our knowledge, this is the first multicenter clinical trial that has employed CD-DST...

Introducing Micrometer-Sized Artificial Objects into Live Cells: A Method for Cell–Giant Unilamellar Vesicle Electrofusion

and its Supporting Information files. Funding: This work was supported by Grants-in-Aid for Scientific Research (#24104004, #22220001 for Satoshi Murata and Shin-ichiro M. Nomura, #25610117 for Shin

Resectable carcinoma developing in the remnant pancreas 7 years and 10 months after distal pancreatectomy for invasive ductal carcinoma of the pancreas: report of a case

Background Pancreatic ductal adenocarcinoma, which represents 90% of pancreatic cancers, is one of the most lethal and aggressive malignancies. Operative resection remains the only treatment providing prolonged survival, however, recurrence of pancreatic ductal adenocarcinoma occurs in up to 80% of patients with pancreatic cancer within 2 years of a potential curative resection...

Molecular Robotics: A New Paradigm for Artifacts

terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. Satoshi Murata: He

Enhanced Intestinal Motility during Oral Glucose Tolerance Test after Laparoscopic Sleeve Gastrectomy: Preliminary Results Using Cine Magnetic Resonance Imaging

Background Enhanced secretion of glucagon-like peptide-1 (GLP-1) has been suggested as a possible mechanism underlying the improvement in type 2 diabetes mellitus (T2DM) after laparoscopic sleeve gastrectomy (LSG). However, the reason for enhanced GLP-1 secretion during glucose challenge after LSG remains unclear because LSG does not include intestinal bypass. In this study, we...

Construction of a genetic AND gate under a new standard for assembly of genetic parts

Background Appropriate regulation of respective gene expressions is a bottleneck for the realization of artificial biological systems inside living cells. The modification of several promoter sequences is required to achieve appropriate regulation of the systems. However, a time-consuming process is required for the insertion of an operator, a binding site of a protein for gene...

Expression of HLA-DR and urokinase-type plasminogen activator in stage IV gastric cancer

Background. Some patients with stage IV gastric cancer have a long survival. Host immune response and proteolytic activity in the primary tumor may be associated with outcome in these patients. The purpose of this study was to assess prognostic factors in patients with stage IV far advanced gastric cancer. Methods. Findings in 26 patients who underwent resection of stage IV...