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Infectious endophthalmitis leading to evisceration: spectrum of bacterial and fungal pathogens and antibacterial susceptibility profile

PurposeTo describe the spectrum of bacterial and fungal pathogens in cases of endophthalmitis requiring evisceration and report their antimicrobial susceptibilities.MethodsRetrospective, consecutive, and descriptive case series of endophthalmitis that underwent evisceration from January 2004 to December 2017. Vitreous samples from all patients had been investigated for bacteria...

Filamentous gram-negative bacteria masquerading as actinomycetes in infectious endophthalmitis: a review of three cases

BackgroundTo report microbiological diagnostic dilemma posed by observation of unusual morphology of bacteria in the vitreous sample of a series of three cases of bacterial endophthalmitis.ResultsA non-comparative, descriptive case series is described. All three cases presented to the retina-vitreous clinic with a clinical diagnosis of acute endophthalmitis between January and...

Elevated cytokine levels in vitreous as biomarkers of disease severity in infectious endophthalmitis

Chakrabarti. Investigation: Mudit Tyagi. Methodology: Dhanshree Deshmukh, Moumita Chakrabarti, Rajagopalaboopathi Jayasudha. Project administration: Savitri Sharma, Joveeta Joseph. Resources: Joveeta Joseph ... ? review & editing: Mudit Tyagi, Savitri Sharma, Joveeta Joseph. 1. Kernt M , Kampik A . Endophthalmitis: pathogenesis, clinical presentation, management, and perspectives . Clin Ophthalmol . 2010 ; 4 : 121

Alterations in the gut bacterial microbiome in fungal Keratitis patients

administration: Sisinthy Shivaji. Resources: Savitri Sharma, Prashant Garg, Somasheila I. Murthy, Sisinthy Shivaji. Software: Anirban Dutta, Nishal Kumar Pinna, Sharmila S. Mande. Supervision: Sisinthy Shivaji

Clinical and microbiological profile of non-tuberculous mycobacterial endophthalmitis—experience in a tertiary eye care centre in Southern India

BackgroundEndophthalmitis caused by non-tuberculous mycobacteria (NTM) is a rare condition seen after surgery and trauma. This study reports a retrospective, consecutive, non-comparative case series of 5 patients referred to L. V. Prasad Eye Institute, Hyderabad, and diagnosed with culture-proven NTM endophthalmitis between January 2004 and April 2015. Data collected included...

Identification of Novel Sequence Types among Staphylococcus haemolyticus Isolated from Variety of Infections in India

The aim of this study was to determine sequence types of 34 S. haemolyticus strains isolated from a variety of infections between 2013 and 2016 in India by MLST. The MEGA5.2 software was used to align and compare the nucleotide sequences. The advanced cluster analysis was performed to define the clonal complexes. MLST analysis showed 24 new sequence types (ST) among S...

Comparison of clinico-microbiological profile and treatment outcome of in-house and referred post cataract surgery endophthalmitis in a tertiary care center in South India

BackgroundThe purpose of the study is to compare the clinico-microbiological profile and treatment outcome of in-house vs referred cases of post cataract surgery endophthalmitis in a tertiary eye care facility in South India.MethodsThe clinical records of 50 culture-positive cases each of in-house (group A) and referred (group B) post cataract surgery endophthalmitis were...

Fungal scleritis masquerading as surgically induced necrotizing scleritis: a case report

Introduction The object of this case is to report the clinical findings, microbiological findings and management of a case of fungal scleritis following cataract surgery, which mimicked surgically induced necrotizing scleritis. Case presentation A 72-year-old Asian (Indian) man presented with scleritis following cataract surgery at another facility. He had been treated elsewhere...

Bacteremia during dacryocystorhinostomy: results of intra-operative blood cultures

Savitri Sharma 1 Milind N Naik 0 0 Dacryology Service, L.V.Prasad Eye Institute , Hyderabad 34 , India 1 Jhaveri Microbiology Center, L.V.Prasad Eye Institute , Hyderabad 34 , India Background: The aims of

Nontuberculous mycobacterial infection after frontalis sling surgery using silicone rod

Purpose The purpose of this study is to report a case of nontuberculous mycobacterial infection after frontalis sling surgery. Method A 65-year-old man presented with bilateral painful, erythematous lesions in the brow and upper eyelids. He had a history of frontalis sling surgery for myopathic ptosis 2 years back and all lesions were found localized to the tract of the silicone...

Nocardia scleritis—clinical presentation and management: a report of three cases and review of literature

Srikant Kumar Sahu 0 Savitri Sharma 0 Sujata Das 0 0 S. Sharma Ocular Microbiology service, Proff Brien Holden Eye Research Center, L V Prasad Eye Institute , Bhubaneswar, Patia, Bhubaneswar, Orissa

Microbiologic spectrum and susceptibility of isolates in delayed post-cataract surgery endophthalmitis

Raja Narayanan,2 Jay Chhablani,2 Savitri Sharma,3,4 Taraprasad Das,2,3 Harry W Flynn Jr51L V Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, India; 2Srimati Kannuri Santhamma Centre for

Stenotrophomonas maltophilia endogenous endophthalmitis: clinical presentation, antibiotic susceptibility, and outcomes

Motukupally,3 Savitri Sharma,3 Avinash Pathengay,2 Harry W Flynn Jr4 1Srimati Kannuri Santhamma Centre for Vitreoretinal Diseases, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India; 2L V

Degree, duration, and causes of visual impairment in eyes affected with ocular tuberculosis

Background Ocular tuberculosis (TB) can affect nearly every ocular tissue, leading to a variety of vision-threatening clinical manifestations. The goal of this study is to estimate the degree, duration, and causes of visual impairment in eyes affected by ocular TB. Results This was a retrospective study of patients diagnosed as ocular TB based on polymerase chain reaction (PCR...

Clinico-Microbiological Profile and Treatment Outcome of Infectious Scleritis: Experience from a Tertiary Eye Care Center of India

Medical and microbiology records of seventeen patients (17 eyes), diagnosed as scleritis of infectious origin were reviewed; to study clinical features, predisposing risk factors, microbiologic profile and treatment outcome of infectious scleritis. The mean patient age was years. Twelve patients (70.6%) had history of trauma/prior surgery. Isolated organisms included...

Factors influencing polymerase chain reaction outcomes in patients with clinically suspected ocular tuberculosis

Background Polymerase chain reaction (PCR) assay can be a useful method for definitive diagnosis in paucibacillary infections such as ocular tuberculosis (TB). In this study, we have evaluated factors affecting PCR outcomes in patients with clinically suspected ocular TB. Patients with clinically suspected ocular TB were investigated by PCR of aqueous or vitreous samples. Three...

Diagnosis and treatment outcome of mycotic keratitis at a tertiary eye care center in eastern india

BMC Ophthalmology Diagnosis and Treatment Outcome of Mycotic Keratitis at a Tertiary Eye Care Center in Eastern India Bibhudutta Rautaraya 0 Savitri Sharma 0 Sarita Kar 0 Sujata Das 1 Srikant K Sahu

Diagnosis and treatment outcome of mycotic keratitis at a tertiary eye care center in eastern india

Mycotic keratitis is an important cause of corneal blindness world over including India. Geographical location and climate are known to influence the profile of fungal diseases. While there are several reports on mycotic keratitis from southern India, comprehensive clinico-microbiological reports from eastern India are few. The reported prevalence of mycotic keratitis are 36.7...

Staphylococcus aureus eye infections in two Indian hospitals: emergence of ST772 as a major clone

Staphylococcus aureus eye infections in two Indian hospitals: emergence of ST772 as a major clone Savitha Nadig1, Nithya Velusamy2, Prajna Lalitha2, Sarita Kar3, Savitri Sharma3, Gayathri Arakere11Society for Innovation and Development, Indian Institute of Science, Bengaluru, Karnataka, 2Aravind Eye Hospital, Madurai, Tamil Nadu, 3LV Prasad Eye Institute, Bhubaneswar, Odisha...