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Guidelines and recommendations for ensuring Good Epidemiological Practice (GEP): a guideline developed by the German Society for Epidemiology

ObjectiveTo revise the German guidelines and recommendations for ensuring Good Epidemiological Practice (GEP) that were developed in 1999 by the German Society for Epidemiology (DGEpi), evaluated and revised in 2004, supplemented in 2008, and updated in 2014.MethodsThe executive board of the DGEpi tasked the third revision of the GEP. The revision was arrived as a result of a...

Visceral adipose tissue but not subcutaneous adipose tissue is associated with urine and serum metabolites

Obesity is a complex multifactorial phenotype that influences several metabolic pathways. Yet, few studies have examined the relations of different body fat compartments to urinary and serum metabolites. Anthropometric phenotypes (visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), the ratio between VAT and SAT (VSR), body mass index (BMI), waist circumference (WC...

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Context Obesity in men is associated with low serum testosterone and both are associated with several diseases and increased mortality. Objectives Examine the direction and causality of the relationship between body mass index (BMI) and serum testosterone. Design Bi-directional Mendelian randomization (MR) analysis on prospective cohorts. Setting Five cohorts from Denmark...

Prevalence and determinants of controlled hypertension in a German population cohort

Background Data of the German population-based cohort SHIP (Study of Health in Pomerania) were analysed to examine treatment rates, antihypertensive substances prescribed, and the proportion of hypertensive study participants reaching target values for blood pressure as well as determinants. Methods The study population was defined using baseline data of the cohort (collected...

Correlates of Adverse Outcomes in Abdominally Obese Individuals: Findings from the Five-Year Followup of the Population-Based Study of Health in Pomerania

 Ulrich John,2,4 Marcus Dörr,2,5 Sebastian E. Baumeister,6 Georg Homuth,2,7 Uwe Völker,2,7 and Henri Wallaschofski1,2 1Institute of Clinical Chemistry and Laboratory Medicine, University Medicine

Effect of the delegation of GP-home visits on the development of the number of patients in an ambulatory healthcare centre in Germany

Neeltje van den Berg 0 Romy Heymann Claudia Meinke 0 Sebastian E Baumeister Steffen Flea Wolfgang Hoffmann 0 0 University Medicine Greifswald, Institute for Community Medicine , Ellernholzstr. 1-2

Effect of the delegation of GP-home visits on the development of the number of patients in an ambulatory healthcare centre in Germany

The AGnES-concept (AGnES: GP-supporting, community-based, e-health-assisted, systemic intervention) was developed to support general practitioners (GPs) in undersupplied regions. The project aims to delegate GP-home visits to qualified AGnES-practice assistants, to increase the number of patients for whom medical care can be provided. This paper focuses on the effect of...

Association between Markers of Fatty Liver Disease and Impaired Glucose Regulation in Men and Women from the General Population: The KORA-F4-Study

Objective To investigate whether the elevated liver enzymes gamma-glutamyltransferase (GGT), glutamate-pyruvate transaminase (GPT), glutamate-oxalacetate transaminase (GOT) and alkaline phosphatase (AP) and non-alcoholic fatty liver disease (NAFLD) respectively are independently associated with pre-diabetic states, namely impaired fasting glucose (IFG) and impaired glucose...

Association between lifestyle factors and headache

Modification of lifestyle habits is a key preventive strategy for many diseases. The role of lifestyle for the onset of headache in general and for specific headache types, such as migraine and tension-type headache (TTH), has been discussed for many years. Most results, however, were inconsistent and data on the association between lifestyle factors and probable headache forms...

Sedative, hypnotic, anxiolytic and opioid medicament use and its co-occurrence with tobacco smoking and alcohol risk drinking in a community sample

Background Sedative, hypnotic, anxiolytic and opioid medicament (SO) use and its relation to tobacco smoking and alcohol risk drinking is largely unknown. Prevalence data for SO intake and its co-occurrence with tobacco smoking and alcohol risk drinking considering age are presented. Methods Random general population sample of individuals aged 20–79 drawn from a mixed rural and...

The Molecular Genetic Architecture of Self-Employment

. Ankra-Badu Sebastian E. Baumeister Daniel J. Benjamin Reiner Biffar Stefan Blankenberg Dorret I. Boomsma David Cesarini Francesco Cucca Eco J. C. de Geus George Dedoussis Panos Deloukas Maria Dimitriou