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LDH-A promotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer

LDH-A promotes epithelial-mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer Yongjie Zhang,1,2,* Sen Lin,3,* Yan Chen,2,* Fei Yang,2 Shenlin Liu1 1Department of

Variations in eco-enzymatic stoichiometric and microbial characteristics in paddy soil as affected by long-term integrated organic-inorganic fertilization

China (2013CB127403) and the National Science and Technology Major Project of China (2014ZX07101-012). Author Contributions Conceptualization: Shaoxian Wang, Wuzhong Ni. Data curation: Sen Lin ... , Shaoxian Wang. Formal analysis: Sen Lin, Wuzhong Ni. Funding acquisition: Wuzhong Ni. Software: Sen Lin. Writing ± original draft: Sen Lin, Wuzhong Ni. Methodology: Sen Lin, Shaoxian Wang, Yuanli Si

Identification of differentially expressed genes through RNA sequencing in goats (Capra hircus) at different postnatal stages

, differentially expressed genes, and annotations. (XLSX) Author Contributions Conceptualization: Yong Wang. Data curation: Yaqiu Lin. Funding acquisition: Yong Wang. Methodology: Qian Li, Sen Lin. Project ... administration: Yong Wang. Supervision: Yong Wang. Validation: Qian Li, Sen Lin. Writing ± original draft: Jiangjiang Zhu. Writing ± review & editing: Yaqiu Lin, Jiangjiang Zhu. 13 / 15 14 / 15 32. 1. De

Room-temperature processing of silver submicron fiber mesh for flexible electronics

AffiliationsState Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, ChinaXiaopeng Bai, Sen Lin, Haolun Wang, Yi Zong, Haiyang Wang ... , Ziyun Huang, Donglai Li, Chang Wang & Hui Wu AuthorsSearch for Xiaopeng Bai in:Nature Research journals • PubMed • Google Scholar Search for Sen Lin in:Nature Research journals • PubMed • Google Scholar

Simulation study of activities of daily living functions using online computerized adaptive testing

Background Computer adaptive testing (CAT) of the activities of daily living (ADL) functions is required (i) to reveal the advantages of using an efficient and accurate estimation method, (ii) to determine the cutpoint for classifying ADL strata in patients with stroke, and (iii) to evaluate the feasibility of online CAT used in clinical settings for smartphones. Methods Normally...

Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy

Zhao. Investigation: Lin Mei. Methodology: Fu-Lei Tang, Sen Lin. Project administration: Wen-Cheng Xiong. Software: Fu-Lei Tang. 13 / 16 Supervision: Lin Mei, Jian Ye, Wen-Cheng Xiong. Writing

Dynamics of coral-associated bacterial communities acclimated to temperature stress based on recent thermal history

-Hsing University, Taichung, TaiwanJia-Ho Shiu & Sen-Lin TangBiodiversity Research Center, Academia Sinica, Taipei, TaiwanJia-Ho Shiu, Shashank Keshavmurthy, Pei-Wen Chiang, Hsing-Ju Chen, Shueh-Ping Lou ... , Chaolun Allen Chen & Sen-Lin TangGraduate Institute of Biotechnology, National Chung-Hsing University, Taichung, TaiwanJia-Ho ShiuGermark Biotechnology Co., Ltd., Taichung, 40767, TaiwanChing-Hung

A Kirigami Approach to Forming a Synthetic Buckliball

The shape transformation of some biological systems inspires scientists to create sophisticated structures at the nano- and macro- scales. However, to be useful in engineering, the mechanics of governing such a spontaneous, parallel and large deformation must be well understood. In this study, a kirigami approach is used to fold a bilayer planar sheet featuring a specific pattern...

An APOC3 3′UTR variant associated with plasma triglycerides levels and coronary heart disease by creating a functional miR-4271 binding site

-Gang Jiang & Dao-Wen Wang AuthorsSearch for Sen-Lin Hu in:Nature Research journals • PubMed • Google ScholarSearch for Guang-Lin Cui in:Nature Research journals • PubMed • Google ScholarSearch for Jin

Geographical variations in bacterial communities associated with soft coral Scleronephthya gracillimum

. VD is supported by a grant from the Ministry Of Science and Technology (Taiwan, no. 104-2611-M-002±020 -MY2). Author Contributions Conceptualization: Seonock Woo, Sen-Lin Tang. Data curation: Shan ... -Hua Yang, Hsing-Ju Chen, Yu-Fang Tseng. Formal analysis: Shan-Hua Yang. Funding acquisition: Seonock Woo. Methodology: Seonock Woo, Shan-Hua Yang, Hsing-Ju Chen, Yu-Fang Tseng, Sen-Lin Tang. Project

Accurate reconstruction of viral quasispecies spectra through improved estimation of strain richness

Background Estimating the number of different species (richness) in a mixed microbial population has been a main focus in metagenomic research. Existing methods of species richness estimation ride on the assumption that the reads in each assembled contig correspond to only one of the microbial genomes in the population. This assumption and the underlying probabilistic...

Transient nuclear Prospero induces neural progenitor quiescence

Stem cells can self-renew, differentiate, or enter quiescence. Understanding how stem cells switch between these states is highly relevant for stem cell-based therapeutics. Drosophila neural progenitors (neuroblasts) have been an excellent model for studying self-renewal and differentiation, but quiescence remains poorly understood. In this study, we show that when neuroblasts...

Mammary inflammatory gene expression was associated with reproductive stage and regulated by docosahexenoic acid: in vitro and in vivo studies

Background Periparturient mastitis is the most prevalent disease affecting lactating animals. However, it has long been relied on antibiotics to deal with mastitis, leading to a potential threat to food safety. This study was aimed to investigate the expression of pro-inflammatory cytokines in mammary glands of sows around parturition when mastitis and oxidative stress usually...

Discovery of putative capsaicin biosynthetic genes by RNA-Seq and digital gene expression analysis of pepper

The Indian pepper ‘Guijiangwang’ (Capsicum frutescens L.), one of the world’s hottest chili peppers, is rich in capsaicinoids. The accumulation of the alkaloid capsaicin and its analogs in the epidermal cells of the placenta contribute to the pungency of Capsicum fruits. To identify putative genes involved in capsaicin biosynthesis, RNA-Seq was used to analyze the pepper’s...

Bacterial Community Associated with Organs of Shallow Hydrothermal Vent Crab Xenograpsus testudinatus near Kuishan Island, Taiwan

Shallow-water hydrothermal vents off Kueishan Island (northeastern Taiwan) provide a unique, sulfur-rich, highly acidic (pH 1.75–4.6) and variable-temperature environment. In this species-poor habitat, the crab Xenograpsus testudinatus is dominant, as it mainly feeds on zooplankton killed by sulfurous plumes. In this study, 16S ribosomal RNA gene amplicon pyrosequencing was used...

Buckling-induced retraction of spherical shells: A study on the shape of aperture

experimental test and numerical simulation during buckling process. Photo courtesy of Sen Lin. Full size image It is interesting to make a comparison between physical test and numerical simulation in view ... , Xiaodong Huang & Shiwei ZhouSchool of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, NSW 2006, AustraliaQing Li AuthorsSearch for Sen Lin in:Nature Research journals • PubMed